Variation-based Drug Prioritization |
This page is designed to provide drug prioritization prediction with variations present in the genes. This page is provided with three options: Option1 This module requires variation information of limited number (32) of genes. With a limitation of lower performance, this module only requires selection of variant genes in the given table. Option2 This module is given for better prediction where it requires of list of all variant genes of a genome. User has to submit only variant genes as a list of Hugo names. Option3 This module uses the converted Variant Calling Format (VCF) file of genome sequencing. Since the VCF files are large in size, the user has to convert the VCF file to ANNOVAR input file and then upload it to server. The performances of models in this option is same as option2. Option4 This module has same performace as option2 and uses the raw sequencing file in the form of Variant Calling Format (VCF). User has to submit the VCF file, which is well accepted format for variant information storage. For more information see HELP page. |