Browse result page of B3Pdb

The total number entries retrieved from this search are 507, scroll left/right for detailed information.

B3pdbID	PEPTIDE NAME	PEPTIDE SEQUENCE (1-letter)	PEPTIDE SEQUENCE (3-letter)	N-TERMINAL MODIFICATION	C-TERMINAL MODIFICATION	CHEMICAL MODIFICATION	PEPTIDE LENGTH	PEPTIDE CONFORMATION	PEPTIDE NATURE	SOURCE/ORIGIN OF PEPTIDE	SMILES	CELL LINE	In vitro CONCENTRATION	In vitro METHOD	In vitro RESULT	ANIMAL MODEL	In vivo CONCENTRATION	In vivo MODE OF DELIVERY	In vivo METHOD	In vivo RESULT	ACTION	TRANSPORT TYPE	SUBCELLULAR LOCALISATION	COMBINATION	PHYSICAL CONDITION	RESPONSE	RESULT	LABEL	PMID
b3pdb_1071	Guanidino-Endomorphi	Guan-YPFF-NH2	Guan-Tyr-Pro-Phe-Phe-NH2	NA	NA	NA	4	Linear	NA	Chemically synthesized	NA	NA	NA	BMEC	NA	NA	NA	NA	NA	NA	NA	Permeability	NA	NA	NA	Permeability coefficient	0.00005417 cm/s	Direct iodination	12226841
b3pdb_1072	Morphiceptin	YPFP-NH2	Tyr-Pro-Phe-Pro-NH2	NA	NA	NA	4	Linear	NA	Chemically synthesized	NA	NA	NA	Shake Flask	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	Log D	0.7284	Direct iodination	12226841
b3pdb_1073	Morphiceptin	YPFP-NH2	Tyr-Pro-Phe-Pro-NH2	NA	NA	NA	4	Linear	NA	Chemically synthesized	NA	NA	NA	BMEC	NA	NA	NA	NA	NA	NA	NA	Permeability	NA	NA	NA	Unidirectonal influx rate constant	0.0205 mL/(g x min)	Direct iodination	12226841
b3pdb_1074	Morphiceptin	YPFP-NH2	Tyr-Pro-Phe-Pro-NH2	NA	NA	NA	4	Linear	NA	Chemically synthesized	NA	NA	NA	BMEC	NA	NA	NA	NA	NA	NA	NA	Permeability	NA	NA	NA	Initial distribution Initial distribution Initial distribution Initial distribution Initial distribu	2.86 ml/g	Direct iodination	12226841
b3pdb_1075	Morphiceptin	YPFP-NH2	Tyr-Pro-Phe-Pro-NH2	NA	NA	NA	4	Linear	NA	Chemically synthesized	NA	NA	NA	BMEC	NA	NA	NA	NA	NA	NA	NA	Permeability	NA	NA	NA	Permeability coefficient	0.000051 cm/s	Direct iodination	12226841
b3pdb_1076	Guanidino-Morphicept	Guan-YPFP-NH2	Guan-Tyr-Pro-Phe-Pro-NH2	NA	NA	NA	4	Linear	NA	Chemically synthesized	NA	NA	NA	Shake Flask	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	Log D	-0.3979	Direct iodination	12226841
b3pdb_1077	Guanidino-Morphicept	Guan-YPFP-NH2	Guan-Tyr-Pro-Phe-Pro-NH2	NA	NA	NA	4	Linear	NA	Chemically synthesized	NA	NA	NA	BMEC	NA	NA	NA	NA	NA	NA	NA	Permeability	NA	NA	NA	Unidirectonal influx rate constant	0.0174 mL/(g x min)	Direct iodination	12226841
b3pdb_1078	Guanidino-Morphicept	Guan-YPFP-NH2	Guan-Tyr-Pro-Phe-Pro-NH2	NA	NA	NA	4	Linear	NA	Chemically synthesized	NA	NA	NA	BMEC	NA	NA	NA	NA	NA	NA	NA	Permeability	NA	NA	NA	Initial distribution Initial distribution Initial distribution Initial distribution Initial distribu	2.31 ml/g	Direct iodination	12226841
b3pdb_1079	Guanidino-Morphicept	Guan-YPFP-NH2	Guan-Tyr-Pro-Phe-Pro-NH2	NA	NA	NA	4	Linear	NA	Chemically synthesized	NA	NA	NA	BMEC	NA	NA	NA	NA	NA	NA	NA	Permeability	NA	NA	NA	Permeability coefficient	0.000067 cm/s	Direct iodination	12226841
b3pdb_1080	Phe0-DPDPE	FY-pen-GF-pen	Phe-Tyr-(D)Pen-Gly-Phe-D(Pen)	NA	NA	pen2-pen5	6	Linear	NA	Chemically synthesized	NA	NA	NA	BMEC	NA	NA	NA	NA	NA	NA	NA	Permeability	NA	NA	NA	Permeability coefficient	0.00009657 cm/s	NA	8667199
b3pdb_1081	DPDPE-Phe	Y-pen-GF-pen-F	Tyr-(D)Pen-Gly-Phe-D(Pen)-Phe	NA	NA	pen2-pen5	6	Linear	NA	Chemically synthesized	NA	NA	NA	BMEC	NA	NA	NA	NA	NA	NA	NA	Permeability	NA	NA	NA	Permeability coefficient	0.0000861 cm/s	NA	8667199
b3pdb_1082	DPDPE-Arg-Gly	Y-pen-GF-pen-RG	Tyr-(D)Pen-Gly-Phe-D(Pen)-Arg-Gly	NA	NA	pen2-pen5	7	Linear	NA	Chemically synthesized	NA	NA	NA	BMEC	NA	NA	NA	NA	NA	NA	NA	Permeability	NA	NA	NA	Permeability coefficient	0.000101 cm/s	NA	8667199
b3pdb_1083	DPDPE-Phe-Ala-NH-(CH	Y-pen-GF-pen-FA-NH-(CH2)5-CONH2	Tyr-(D)Pen-Gly-Phe-D(Pen)-Phe-Ala-NH-(CH2)5-CONH2	NA	NA	pen2-pen5	7	Linear	NA	Chemically synthesized	NA	NA	NA	BMEC	NA	NA	NA	NA	NA	NA	NA	Permeability	NA	NA	NA	Permeability coefficient	0.00008333 cm/s	NA	8667199
b3pdb_1084	DPLCE	Y-pen-GFC	Tyr-D(Pen)-Gly-Phe-Cys	NA	NA	pen2-Cys5	5	Linear	NA	Chemically synthesized	NA	NA	NA	BMEC	NA	NA	NA	NA	NA	NA	NA	Permeability	NA	NA	NA	Permeability coefficient	0.0000939 cm/s	NA	8667199
b3pdb_1085	DPLCE-Arg-Pro-Ala	Y-pen-GFCRPA	Tyr-D(Pen)-Gly-Phe-Cys-Arg-Pro-Ala	NA	NA	pen2-Cys5	8	Linear	NA	Chemically synthesized	NA	NA	NA	BMEC	NA	NA	NA	NA	NA	NA	NA	Permeability	NA	NA	NA	Permeability coefficient	0.00009137 cm/s	NA	8667199
b3pdb_1086	Insulin detemir, Lev	A-chain:GIVEQCCTSICSLYQLENYCN B-chain: FVNQHLCGSHLVEALYLVCGERGFFYTPK-myristic acid	A-chain: Gly-Ile-Val-Glu-Gln-Cys-Cys-Thr-Ser-Ile-Cys-Ser-Leu-Tyr-Gln-Leu-Glu-Asn-Tyr-Cys-Asn B-chain:Phe-Val-Asn-Gln-His-Leu-Cys-Gly-Ser-His-Leu-Val-Glu-Ala-Leu-Tyr-Leu-Val-Cys-Gly-Glu-Arg-Gly-Phe-Phe-Tyr-Thr-Pro-Lys-myristic acid	NA	NA	CysA6-CysA11; CysA7-CysB7; CysA20-CysB19	50	Linear	NA	Chemically synthesized	CCCCCCCCCCCCCC(=O)NCCCC[C@@H](C(=O)O)NC(=O)[C@@H]1CCCN1C(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CC2=CC=C(C=C2)O)NC(=O)[C@H](CC3=CC=CC=C3)NC(=O)[C@H](CC4=CC=CC=C4)NC(=O)CNC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@@H]5CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H]6CSSC[C@@H](C(=O)N[C@@H](CSSC[C@@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N5)C(C)C)CC(C)C)CC7=CC=C(C=C7)O)CC(C)C)C)CCC(=O)O)C(C)C)CC(C)C)CC8=CN=CN8)CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC9=CN=CN9)NC(=O)[C@H](CCC(=O)N)NC(=O)[C@H](CC(=O)N)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC1=CC=CC=C1)N)C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N6)[C@@H](C)CC)CO)[C@@H](C)O)NC(=O)[C@H](CCC(=O)N)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](C(C)C)NC(=O)[C@H]([C@@H](C)CC)NC(=O)CN)CO)CC(C)C)CC1=CC=C(C=C1)O)CCC(=O)N)CC(C)C)CCC(=O)O)CC(=O)N)CC1=CC=C(C=C1)O)C(=O)N[C@@H](CC(=O)N)C(=O)O	NA	NA	NA	NA	NA	NA	in situ brain perfusion	NA	NA	NA	Permeability	NA	NA	NA	Unidirectional flux rate constant	0 mL/(g x min)	Direct iodination	25492620
b3pdb_1087	Insulin detemir, Lev	A-chain: Gly-Ile-Val-Glu-Gln-Cys-Cys-Thr-Ser-Ile-Cys-Ser-Leu-Tyr-Gln-Leu-Glu-Asn-Tyr-Cys-Asn B-chain:Phe-Val-Asn-Gln-His-Leu-Cys-Gly-Ser-His-Leu-Val-Glu-Ala-Leu-Tyr-Leu-Val-Cys-Gly-Glu-Arg-Gly-Phe-Phe-Tyr-Thr-Pro-Lys-myristic acid	A-chain:GIVEQCCTSICSLYQLENYCN B-chain: FVNQHLCGSHLVEALYLVCGERGFFYTPK-myristic acid	NA	NA	CysA6-CysA11; CysA7-CysB7; CysA20-CysB19	50	Linear	NA	Chemically synthesized	CCCCCCCCCCCCCC(=O)NCCCC[C@@H](C(=O)O)NC(=O)[C@@H]1CCCN1C(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CC2=CC=C(C=C2)O)NC(=O)[C@H](CC3=CC=CC=C3)NC(=O)[C@H](CC4=CC=CC=C4)NC(=O)CNC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@@H]5CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H]6CSSC[C@@H](C(=O)N[C@@H](CSSC[C@@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N5)C(C)C)CC(C)C)CC7=CC=C(C=C7)O)CC(C)C)C)CCC(=O)O)C(C)C)CC(C)C)CC8=CN=CN8)CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC9=CN=CN9)NC(=O)[C@H](CCC(=O)N)NC(=O)[C@H](CC(=O)N)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC1=CC=CC=C1)N)C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N6)[C@@H](C)CC)CO)[C@@H](C)O)NC(=O)[C@H](CCC(=O)N)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](C(C)C)NC(=O)[C@H]([C@@H](C)CC)NC(=O)CN)CO)CC(C)C)CC1=CC=C(C=C1)O)CCC(=O)N)CC(C)C)CCC(=O)O)CC(=O)N)CC1=CC=C(C=C1)O)C(=O)N[C@@H](CC(=O)N)C(=O)O	NA	NA	NA	NA	NA	NA	Intravenous	NA	NA	NA	Permeability	NA	NA	NA	Unidirectional influx rate constant	0 mL/(g x min)	Direct iodination	20868713
b3pdb_1088	Ziconotide, SNX-111,	CKGKGAKCSRLMYDCCTGSCRSGKC	Cys-Lys-Gly-Lys-Gly-Ala-Lys-Cys-Ser-Arg-Leu-Met-Tyr-Asp-Cys-Cys-Thr-Gly-Ser-Cys-Arg-Ser-Gly-Lys-Cys	NA	NA	Cys1-Cys16; Cys8-Cys20; Cys15-Cys25	25	Linear	NA	Chemically synthesized	C[C@H]1C(=O)N[C@H](C(=O)N[C@H]2CSSC[C@H]3C(=O)N[C@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)NCC(=O)N1)CCCCN)CCCCN)N)C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N3)CO)[C@@H](C)O)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC2=O)CO)CCCNC(=N)N)CC(C)C)CCSC)CC4=CC=C(C=C4)O)CC(=O)O)C(=O)N)CCCCN)CO)CCCNC(=N)N)CCCCN	NA	NA	NA	NA	NA	NA	in situ brain perfusion	NA	NA	NA	Permeability	NA	NA	NA	Unidirectional flux rate constant	0.0042 mL/(g x min)	Direct iodination	10822104
b3pdb_1089	Ziconotide, SNX-111,	CKGKGAKCSRLMYDCCTGSCRSGKC	Cys-Lys-Gly-Lys-Gly-Ala-Lys-Cys-Ser-Arg-Leu-Met-Tyr-Asp-Cys-Cys-Thr-Gly-Ser-Cys-Arg-Ser-Gly-Lys-Cys	NA	NA	Cys1-Cys16; Cys8-Cys20; Cys15-Cys25	25	Linear	NA	Chemically synthesized	C[C@H]1C(=O)N[C@H](C(=O)N[C@H]2CSSC[C@H]3C(=O)N[C@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)NCC(=O)N1)CCCCN)CCCCN)N)C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N3)CO)[C@@H](C)O)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC2=O)CO)CCCNC(=N)N)CC(C)C)CCSC)CC4=CC=C(C=C4)O)CC(=O)O)C(=O)N)CCCCN)CO)CCCNC(=N)N)CCCCN	NA	NA	NA	NA	NA	NA	in situ brain perfusion	NA	NA	NA	Permeability	NA	NA	NA	Initial distribution vaolume	0.0018 ml/g	Direct iodination	10822104
b3pdb_1090	Ziconotide, SNX-111,	CKGKGAKCSRLMYDCCTGSCRSGKC	Cys-Lys-Gly-Lys-Gly-Ala-Lys-Cys-Ser-Arg-Leu-Met-Tyr-Asp-Cys-Cys-Thr-Gly-Ser-Cys-Arg-Ser-Gly-Lys-Cys	NA	NA	Cys1-Cys16; Cys8-Cys20; Cys15-Cys25	25	Linear	NA	Chemically synthesized	C[C@H]1C(=O)N[C@H](C(=O)N[C@H]2CSSC[C@H]3C(=O)N[C@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)NCC(=O)N1)CCCCN)CCCCN)N)C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N3)CO)[C@@H](C)O)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC2=O)CO)CCCNC(=N)N)CC(C)C)CCSC)CC4=CC=C(C=C4)O)CC(=O)O)C(=O)N)CCCCN)CO)CCCNC(=N)N)CCCCN	NA	NA	Capillary depletion	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	Rpellet	1.31%	Direct iodination	10822104
b3pdb_1091	Ziconotide, SNX-111,	CKGKGAKCSRLMYDCCTGSCRSGKC	Cys-Lys-Gly-Lys-Gly-Ala-Lys-Cys-Ser-Arg-Leu-Met-Tyr-Asp-Cys-Cys-Thr-Gly-Ser-Cys-Arg-Ser-Gly-Lys-Cys	NA	NA	Cys1-Cys16; Cys8-Cys20; Cys15-Cys25	25	Linear	NA	Chemically synthesized	C[C@H]1C(=O)N[C@H](C(=O)N[C@H]2CSSC[C@H]3C(=O)N[C@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)NCC(=O)N1)CCCCN)CCCCN)N)C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N3)CO)[C@@H](C)O)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC2=O)CO)CCCNC(=N)N)CC(C)C)CCSC)CC4=CC=C(C=C4)O)CC(=O)O)C(=O)N)CCCCN)CO)CCCNC(=N)N)CCCCN	NA	NA	Capillary depletion	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	Rsupernatant	5.58%	Direct iodination	10822104
b3pdb_1092	SNX-194	CKGKGAKCSRL-Nle-YDCCTGSCRSGKC	Cys-Lys-Gly-Lys-Gly-Ala-Lys-Cys-Ser-Arg-Leu-Nle-Tyr-Asp-Cys-Cys-Thr-Gly-Ser-Cys-Arg-Ser-Gly-Lys-Cys	NA	NA	Cys1-Cys16; Cys8-Cys20; Cys15-Cys25	25	Linear	NA	Chemically synthesized	NA	NA	NA	BMEC	NA	NA	NA	NA	NA	NA	NA	Permeability	NA	NA	NA	Permeability coefficient	0.00001083 cm/s	NA	10822104
b3pdb_1093	SNX-231	CKGKGA-Hyp-CRKTMYDCCSGSCGRRGKC	Cys-Lys-Gly-Lys-Gly-Ala-Hyp-Cys-Arg-Lys-Thr-Met-Tyr-Asp-Cys-Cys-Ser-Gly-Ser-Cys-Gly-Arg-Arg-Gly-Lys-Cys	NA	NA	Cys1-Cys16; Cys8-Cys20; Cys15-Cys26	26	Linear	NA	Chemically synthesized	NA	NA	NA	BMEC	NA	NA	NA	NA	NA	NA	NA	Permeability	NA	NA	NA	Permeability coefficient	0.00001317 cm/s	NA	10822104
b3pdb_1094	SNX-185	CLS-Hyp-GSSCS-Hyp-TSYNCCRSCN-Hyp-YSRKCR	Cys-Leu-Ser-Hyp-Gly-Ser-Ser-Cys-Ser-Hyp-Thr-Ser-Tyr-Asn-Cys-Cys-Arg-Ser-Cys-Asn-Hyp-Tyr-Ser-Arg-Lys-Cys-Arg	NA	NA	Cys1-Cys16; Cys8-Cys20; Cys15-Cys26	27	Linear	NA	Chemically synthesized	NA	NA	NA	BMEC	NA	NA	NA	NA	NA	NA	NA	Permeability	NA	NA	NA	Permeability coefficient	0.0000145 cm/s	NA	10822104
b3pdb_1095	THRPPMWSPVWP-NH2	THRPPMWSPVWP-NH2	Thr-His-Arg-Pro-Pro-Met-Trp-Ser-Pro-Val-Trp-Pro-NH2	NA	NA	NA	12	Linear	NA	Chemically synthesized	N[C@@]([H])([C@]([H])(O)C)C(=O)N[C@@]([H])(CC1=CN=C-N1)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)N1[C@@]([H])(CCC1)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CCSC)C(=O)N[C@@]([H])(CC(=CN2)C1=C2C=CC=C1)C(=O)N[C@@]([H])(CO)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CC(=CN2)C1=C2C=CC=C1)C(=O)N1[C@@]([H])(CCC1)C(=O)O	NA	NA	Initial concentration in donor chamber-Culture	NA	NA	NA	NA	NA	NA	NA	Saturable	NA	NA	NA	Parallel artificial membrane permeation assay apparent permiability cofficient	0.0000125 cm/s	NA	25650865
b3pdb_1096	T(NMe)H(NMe)RPPM(NMe	T(NMe)H(NMe)RPPM(NMe)WSPVWP-NH2	Thr-(NMe)-His-(NMe)-Arg-Pro-Pro-Met-(NMe)-Trp-Ser-Pro-Val-Trp-Pro-NH2	NA	NA	NA	12	Linear	NA	Chemically synthesized	NA	NA	NA	Initial concentration in donor chamber-Culture	NA	NA	NA	NA	NA	NA	NA	Saturable	NA	NA	NA	Parallel artificial membrane permeation assay apparent permiability cofficient	0.0000099 cm/s	NA	25650865
b3pdb_1097	THRPPMWSPVWP-NH2	THRPPMWSPVWP-NH2	(D)Thr-(D)His-(D)Arg-(D)Pro-(D)Pro-(D)Met-(D)Trp-(D)Ser-(D)Pro-(D)Val-(D)Trp-(D)Pro-NH2	NA	NA	NA	12	Linear	NA	Chemically synthesized	N[C@@]([H])([C@]([H])(O)C)C(=O)N[C@@]([H])(CC1=CN=C-N1)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)N1[C@@]([H])(CCC1)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CCSC)C(=O)N[C@@]([H])(CC(=CN2)C1=C2C=CC=C1)C(=O)N[C@@]([H])(CO)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CC(=CN2)C1=C2C=CC=C1)C(=O)N1[C@@]([H])(CCC1)C(=O)O	NA	NA	Initial concentration in donor chamber-Culture	NA	NA	NA	NA	NA	NA	NA	Saturable	NA	NA	NA	Parallel artificial membrane permeation assay apparent permiability cofficient	0.0000145 cm/s	NA	25650865
b3pdb_1098	PWVPSWMPPRHT-NH2	PWVPSWMPPRHT-NH2	(D)Pro-(D)Trp-(D)Val)-(D)Pro-(D)Ser-(D)Trp-(D)Met-(D)Pro-(D)Pro-(D)Arg-(D)His-(D)Thr-NH2	NA	NA	NA	12	Linear	NA	Chemically synthesized	N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CC(=CN2)C1=C2C=CC=C1)C(=O)N[C@@]([H])(C(C)C)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])(CC(=CN2)C1=C2C=CC=C1)C(=O)N[C@@]([H])(CCSC)C(=O)N1[C@@]([H])(CCC1)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)N[C@@]([H])(CC1=CN=C-N1)C(=O)N[C@@]([H])([C@]([H])(O)C)C(=O)O	NA	NA	Initial concentration in donor chamber-Culture	NA	NA	NA	NA	NA	NA	NA	Saturable	NA	NA	NA	Parallel artificial membrane permeation assay apparent permiability cofficient	0.0000214 cm/s	NA	25650865
b3pdb_1099	ANG4043, Angiopep2-a	NA	NA	NA	NA	NA	NA	Linear	NA	Chemically synthesized	NA	NA	NA	NA	NA	NA	NA	in situ brain perfusion	NA	NA	NA	saturable	NA	NA	NA	Unidirectional flux rate constant	0.096 mL/(g x min)	Direct iodination	25492620
b3pdb_1100	ANG4043, Angiopep2-a	NA	NA	NA	NA	NA	NA	Linear	NA	Chemically synthesized	NA	NA	NA	Capillary depletion	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	% parenchyma	60%	Direct iodination	25492620
b3pdb_1101	ANG4043, Angiopep2-a	NA	NA	NA	NA	NA	NA	Linear	NA	Chemically synthesized	NA	NA	NA	Capillary depletion	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	% capillary	40%	Direct iodination	25492620
b3pdb_1102	Opiorphin	QRFSR	Gln-Arg-Phe-Ser-Arg	NA	NA	NA	5	Linear	NA	Chemically synthesized	N[C@@]([H])(CCC(=O)N)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)O	NA	NA	Initial concentration in donor chamber-Culture	NA	NA	NA	NA	NA	NA	NA	Saturable	NA	NA	NA	Parallel artificial membrane permeation assay apparent permiability cofficient	0.00000053 cm/s	NA	26143971
b3pdb_1103	des-Tyrosine1-D-Phen	PFPG	Pro-D-Phe-Pro-Gly	NA	NA	NA	4	Linear	NA	Chemically synthesized	N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N1[C@@]([H])(CCC1)C(=O)NCC(=O)O	NA	NA	Initial concentration in donor chamber-Culture	NA	NA	NA	NA	NA	NA	NA	non saturable	NA	NA	NA	Permeability index	18 (x 10-4) cm/min	H3/C14	1620656
b3pdb_1106	PhrANTH2	SKDYN	Ser-Lys-Asp-Tyr-Asn	NA	NA	NA	5	Linear	NA	Chemically synthesized	NA	NA	NA	Efflux study ICU	NA	NA	NA	NA	NA	NA	NA	Permeability	NA	NA	NA	Brain elemination rate constant	-0.05 min-1	Direct iodination	26536593
b3pdb_1107	PhrANTH2	SKDYN	Ser-Lys-Asp-Tyr-Asn	NA	NA	NA	5	Linear	NA	Chemically synthesized	NA	NA	NA	Capillary depletion	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	% parenchyma	79.40%	Direct iodination	26536593
b3pdb_1108	PhrANTH2	SKDYN	Ser-Lys-Asp-Tyr-Asn	NA	NA	NA	5	Linear	NA	Chemically synthesized	NA	NA	NA	Capillary depletion	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	% capillary	20.60%	Direct iodination	26536593
b3pdb_1109	PhrANTH2	SKDYN	Ser-Lys-Asp-Tyr-Asn	NA	NA	NA	5	Linear	NA	Chemically synthesized	NA	NA	NA	NA	NA	NA	NA	Intravenous	NA	NA	NA	Permeability	NA	NA	NA	Unidirectional influx rate constant	0.00018 mL/(g x min)	Direct iodination	26536593
b3pdb_1110	PhrANTH2	SKDYN	Ser-Lys-Asp-Tyr-Asn	NA	NA	NA	5	Linear	NA	Chemically synthesized	NA	NA	NA	NA	NA	NA	NA	Intravenous	NA	NA	NA	Permeability	NA	NA	NA	Initial disrobution volume	0.00659 ml/g	Direct iodination	26536593
b3pdb_1111	BIP-2	GLWEDLLYNINRYAHYIT	Gly-Leu-Trp-Glu-Asp-Leu-Leu-Tyr-Asn-Ile-Asn-Arg-Tyr-Ala-His-Tyr-Ile-Thr	NA	NA	NA	18	Linear	NA	Chemically synthesized	NA	NA	NA	Efflux study ICU	NA	NA	NA	NA	NA	NA	NA	Permeability	NA	NA	NA	Brain elemination rate constant	0.06 min-1	Direct iodination	26536593
b3pdb_1112	BIP-2	GLWEDLLYNINRYAHYIT	Gly-Leu-Trp-Glu-Asp-Leu-Leu-Tyr-Asn-Ile-Asn-Arg-Tyr-Ala-His-Tyr-Ile-Thr	NA	NA	NA	18	Linear	NA	Chemically synthesized	NA	NA	NA	Capillary depletion	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	% parenchyma	76.90%	Direct iodination	26536593
b3pdb_1113	BIP-2	GLWEDLLYNINRYAHYIT	Gly-Leu-Trp-Glu-Asp-Leu-Leu-Tyr-Asn-Ile-Asn-Arg-Tyr-Ala-His-Tyr-Ile-Thr	NA	NA	NA	18	Linear	NA	Chemically synthesized	NA	NA	NA	Capillary depletion	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	% capillary	23.10%	Direct iodination	26536593
b3pdb_1114	BIP-2	GLWEDLLYNINRYAHYIT	Gly-Leu-Trp-Glu-Asp-Leu-Leu-Tyr-Asn-Ile-Asn-Arg-Tyr-Ala-His-Tyr-Ile-Thr	NA	NA	NA	18	Linear	NA	Chemically synthesized	NA	NA	NA	NA	NA	NA	NA	Intravenous	NA	NA	NA	Permeability	NA	NA	NA	Unidirectional influx rate constant	0.00035 mL/(g x min)	Direct iodination	26536593
b3pdb_1115	BIP-2	GLWEDLLYNINRYAHYIT	Gly-Leu-Trp-Glu-Asp-Leu-Leu-Tyr-Asn-Ile-Asn-Arg-Tyr-Ala-His-Tyr-Ile-Thr	NA	NA	NA	18	Linear	NA	Chemically synthesized	NA	NA	NA	NA	NA	NA	NA	Intravenous	NA	NA	NA	Permeability	NA	NA	NA	Initial disrobution volume	0.01267 ml/g	Direct iodination	26536593
b3pdb_1143	[Ala7-C-αGal]dermorp	YaFGYPS-NH2	Tyr-(D)Ala-Phe-Gly-Tyr-Pro-Ser-NH2	NA	NA	NA	7	Linear	NA	Chemically synthesized	NA	NA	NA	anti-nociception	NA	NA	NA	NA	NA	NA	NA	Permeability	NA	NA	NA	ICV/SC ratio	0.0000334	NA	9723966
b3pdb_1144	[Ala7-C-αGal(Ac)4]de	YaFGYPS-NH2	NA	NA	NA	NA	7	Linear	NA	Chemically synthesized	NA	NA	NA	anti-nociception	NA	NA	NA	NA	NA	NA	NA	Permeability	NA	NA	NA	ICV/SC ratio	0.0000089	NA	NA
b3pdb_1145	gH625	HGLASTLTRWAHYNALIRA	His-Gly-Leu-Ala-Ser-Thr-Leu-Thr-Arg-Trp-Ala-His-Tyr-Asn-Ala-Leu-Ile-Arg-Ala	NA	NA	NA	19	Linear	NA	Chemically synthesized	NA	NA	NA	Imaging techniques	NA	NA	NA	NA	NA	NA	NA	Permeability	NA	NA	NA	Brain to plasma ratio	0.09	Fluorescent label	25792823
b3pdb_1146	D1	QSHYRHISPAQV	D-Gln-D-Ser-D-His-D-Tyr-D-Arg-D-His-D-Ile-D-Ser-D-Pro-D-Ala-D-Gln-D-Val	NA	NA	NA	12	Linear	NA	Chemically synthesized	N[C@@]([H])(CCC(=O)N)C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])(CC1=CN=C-N1)C(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)N[C@@]([H])(CC1=CN=C-N1)C(=O)N[C@@]([H])([C@]([H])(CC)C)C(=O)N[C@@]([H])(CO)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CCC(=O)N)C(=O)N[C@@]([H])(C(C)C)C(=O)O	NA	NA	Initial concentration in donor chamber-Culture	NA	NA	NA	NA	NA	NA	NA	non saturable	NA	NA	NA	Permeability index	3.8 (x 10-4) cm/min	NA	19954305
b3pdb_1147	D3	RPRTRLHTHRNR	D-Arg-D-Pro-D-Arg-D-Thr-D-Arg-D-Leu-D-His-D-Thr-D-His-D-Arg-D-Asn-D-Arg	NA	NA	NA	12	Linear	NA	Chemically synthesized	N[C@@]([H])(CCCNC(=N)N)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)N[C@@]([H])([C@]([H])(O)C)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CC1=CN=C-N1)C(=O)N[C@@]([H])([C@]([H])(O)C)C(=O)N[C@@]([H])(CC1=CN=C-N1)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)N[C@@]([H])(CC(=O)N)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)O	NA	NA	Initial concentration in donor chamber-Culture	NA	NA	NA	NA	NA	NA	NA	Saturable	NA	NA	NA	Permeability index	9.5 (x 10-4) cm/min	NA	19954305
b3pdb_1148	D3	RPRTRLHTHRNR	D-Arg-D-Pro-D-Arg-D-Thr-D-Arg-D-Leu-D-His-D-Thr-D-His-D-Arg-D-Asn-D-Arg	NA	NA	NA	12	Linear	NA	Chemically synthesized	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	Permeability	NA	NA	NA	% injected dose	0.14 %/g	H3/C14	27423267
b3pdb_1149	D3	RPRTRLHTHRNR	D-Arg-D-Pro-D-Arg-D-Thr-D-Arg-D-Leu-D-His-D-Thr-D-His-D-Arg-D-Asn-D-Arg	NA	NA	NA	12	Linear	NA	Chemically synthesized	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	Permeability	NA	NA	NA	Brain to plasma ratio	0.8	H3/C14	27423267