Detailed description page of B3Pdb


This page provides detail information of Selected ID b3pdb_1090
Primary information
B3PDB IDb3pdb_1090
Peptide NameZiconotide, SNX-111,
PEPTIDE SEQUENCE (1-letter)CKGKGAKCSRLMYDCCTGSCRSGKC
PEPTIDE SEQUENCE (3-letter)Cys-Lys-Gly-Lys-Gly-Ala-Lys-Cys-Ser-Arg-Leu-Met-Tyr-Asp-Cys-Cys-Thr-Gly-Ser-Cys-Arg-Ser-Gly-Lys-Cys
N-terminal modificationNA
C-terminal modificationNA
Chemical modificationCys1-Cys16; Cys8-Cys20; Cys15-Cys25
Peptide Length25
ConformationLinear
Peptide NatureNA
Source/Origin of peptideChemically synthesized
SMILESC[C@H]1C(=O)N[C@H](C(=O)N[C@H]2CSSC[C@H]3C(=O)N[C@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)NCC(=O)N1)CCCCN)CCCCN)N)C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N3)CO)[C@@H](C)O)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC2=O)CO)CCCNC(=N)N)CC(C)C)CCSC)CC4=CC=C(C=C4)O)CC(=O)O)C(=O)N)CCCCN)CO)CCCNC(=N)N)CCCCN
Cell LineNA
In vitro CONCENTRATIONNA
In vitro METHODCapillary depletion
In vitro RESULTNA
ANIMAL MODELNA
In vivo CONCENTRATIONNA
In vivo MODE OF DELIVERYNA
In vivo METHODNA
In vivo RESULTNA
ACTIONNA
TRANSPORT TYPENA
SUBCELLULAR LOCALISATIONNA
COMBINATIONNA
PHYSICAL CONDITIONNA
RESPONSERpellet
RESULT1.31%
LABELDirect iodination
PMID10822104