Browse result page of B3Pdb

The total number entries retrieved from this search are 507, scroll left/right for detailed information.

B3pdbID	PEPTIDE NAME	PEPTIDE SEQUENCE (1-letter)	PEPTIDE SEQUENCE (3-letter)	N-TERMINAL MODIFICATION	C-TERMINAL MODIFICATION	CHEMICAL MODIFICATION	PEPTIDE LENGTH	PEPTIDE CONFORMATION	PEPTIDE NATURE	SOURCE/ORIGIN OF PEPTIDE	SMILES	CELL LINE	In vitro CONCENTRATION	In vitro METHOD	In vitro RESULT	ANIMAL MODEL	In vivo CONCENTRATION	In vivo MODE OF DELIVERY	In vivo METHOD	In vivo RESULT	ACTION	TRANSPORT TYPE	SUBCELLULAR LOCALISATION	COMBINATION	PHYSICAL CONDITION	RESPONSE	RESULT	LABEL	PMID
b3pdb_1217	P21	VQIVYK	NA	NA	C-terminal amidation	NA	6	Linear	NA	Chemically synthesized	NA	Human brain endothelial cells (EA.hy926)	NA	Field-emission transmission electron microscope	A3 peptide treated with this peptide, showed higher folds of decrease in fluorescence intensities a	NA	NA	NA	NA	NA	Trojan peptides are capable of translo- cating the BBB, without affecting its interity.	Translocation	NA	Comined with A3 pepide	Tauopathies	These peptides were capable of reducing the tau elicit toxicity by accelerating or impeding the self	These peptide-based modulators (Trojans) were non-amyloidogenic, stable in serum and showed minimal	NA	32114026
b3pdb_1218	dNP2	KIKKVKKKGRKGSKIKKVKKKGRK	NA	NA	NA	NA	24	NA	Cationic	Chemically synthesized	NA	Jurkat cells	2 μM	Confocal microscopy	dNP2 enables the delivery of LRR domain of NLRX1 into T cells	C57BL/6J Mice	NA	Intraperitoneal	Confocal microscopy	dNP2 enables the delivery of LRR domain of NLRX1 into T cells	It directly inhibits the functions of effector T cells and ameliorates disease severity of EAE with	NA	NA	Combined with LRR	Encephalomyelitis	NA	NA	NA	32194859
b3pdb_1219	CGKRK-PEG-DSPE	CGKRK	NA	NA	NA	NA	5	NA	NA	Chemically synthesized	NA	U87MG cells	NA	Fluorescent microscopy	It exhibited enhanced transportation	Mice	NA	Intravenous	Fluorescence imaging analysis	It penetrated across the BBB to accumulate at tumor sites with the assistance of Bor and active glio	CGKRK-PSNPs combined with borneol could improve the anti-glioma efficacy with the prolonged medium s	Transcytosis	NA	Combined with borneol	Glioblastoma	NA	NA	NA	32425792
b3pdb_1220	CL peptide	RLLRLLRRRRRRRR	NA	NA	NA	NA	14	Linear	Cationic	Chemically synthesized	NA	MDCKII cells	NA	Confocal microscopy	CL peptide, significantly enhanced the delivery of small-molecule cargo across confluent cell monola	NA	NA	NA	NA	NA	It plays a synergistic role in the transcellular cargo delivery	Permeability	NA	Combined with linker	NA	NA	NA	NA	32474121
b3pdb_1222	AP9	NPNDKYEPF	NA	NA	C-terminal amidation	NA	9	Linear	NA	Chemically synthesized	NA	NA	NA	NA	NA	Mice	20 mg/kg	Intravenous	Evans blue dye	The preservation of the protective effect of double AP9 administration in the postischemic period.	It induce β-arrestin-2-dependent cytoprotective pathways.	NA	NA	Alone	Photothrombosis - induced ischemia	NA	NA	NA	32547356
b3pdb_1223	D-penetratin	RQIKIWFQNRRMKWKK	NA	NA	NA	NA	16	NA	NA	Chemically synthesized	NA	In situ brain perfusion technique	NA	Capillary depletion method	Vectorization of dox led to a 20-fold increase in the amount of dox transportation.	Male Sprague-Dawley rats	2.5 mg/kg	Intravenous	Capillary depletion method	It led to a significant increase in brain dox concentrations during the first 30 min of postadminist	The use of these peptide vectors for brain delivery of dox.	Transcytosis	Brain parenchyma	Combined with Doxorubicin	NA	NA	NA	NA	10727512
b3pdb_1224	SynB1	RGGRLSYSRRRFSTSTGR	NA	NA	NA	NA	18	NA	NA	Chemically synthesized	NA	In situ brain perfusion technique	NA	Capillary depletion method	Vectorization of dox led to a 20-fold increase in the amount of dox transportation.	Male Sprague-Dawley rats	2.5 mg/kg	Intravenous	Capillary depletion method	It led to a significant increase in brain dox concentrations during the first 30 min of postadminist	The use of these peptide vectors for brain delivery of dox.	Transcytosis	Brain parenchyma	Combined with Doxorubicin	NA	NA	NA	NA	10727512