Browse result page of B3Pdb

The total number entries retrieved from this search are 335, scroll left/right for detailed information.
B3pdbIDPEPTIDE NAMEPEPTIDE SEQUENCE (1-letter)PEPTIDE SEQUENCE (3-letter)N-TERMINAL MODIFICATIONC-TERMINAL MODIFICATION CHEMICAL MODIFICATIONPEPTIDE LENGTHPEPTIDE CONFORMATIONPEPTIDE NATURESOURCE/ORIGIN OF PEPTIDESMILESCELL LINEIn vitro CONCENTRATIONIn vitro METHODIn vitro RESULTANIMAL MODELIn vivo CONCENTRATIONIn vivo MODE OF DELIVERYIn vivo METHODIn vivo RESULTACTIONTRANSPORT TYPESUBCELLULAR LOCALISATIONCOMBINATIONPHYSICAL CONDITIONRESPONSERESULTLABELPMID
b3pdb_1069Guanidino-EndomorphiGuan-YPFF-NH2Guan-Tyr-Pro-Phe-Phe-NH2NANANA4LinearNAChemically synthesizedNANANABMECNANANANANANA NA Permeability NA NA NA Unidirectonal influx rate constant 0.0574 mL/(g x min) Direct iodination 12226841
b3pdb_1070Guanidino-EndomorphiGuan-YPFF-NH2Guan-Tyr-Pro-Phe-Phe-NH2NANANA4LinearNAChemically synthesizedNANANABMECNANANANANANA NA Permeability NA NA NA Initial distribution Initial distribution Initial distribution Initial distribution Initial distribu 7.21 ml/g Direct iodination 12226841
b3pdb_1071Guanidino-EndomorphiGuan-YPFF-NH2Guan-Tyr-Pro-Phe-Phe-NH2NANANA4LinearNAChemically synthesizedNANANABMECNANANANANANA NA Permeability NA NA NA Permeability coefficient 0.00005417 cm/s Direct iodination 12226841
b3pdb_1072MorphiceptinYPFP-NH2Tyr-Pro-Phe-Pro-NH2NANANA4LinearNAChemically synthesizedNANANAShake FlaskNANANANANANA NA NA NA NA NA Log D 0.7284 Direct iodination 12226841
b3pdb_1073MorphiceptinYPFP-NH2Tyr-Pro-Phe-Pro-NH2NANANA4LinearNAChemically synthesizedNANANABMECNANANANANANA NA Permeability NA NA NA Unidirectonal influx rate constant 0.0205 mL/(g x min) Direct iodination 12226841
b3pdb_1074MorphiceptinYPFP-NH2Tyr-Pro-Phe-Pro-NH2NANANA4LinearNAChemically synthesizedNANANABMECNANANANANANA NA Permeability NA NA NA Initial distribution Initial distribution Initial distribution Initial distribution Initial distribu 2.86 ml/g Direct iodination 12226841
b3pdb_1075MorphiceptinYPFP-NH2Tyr-Pro-Phe-Pro-NH2NANANA4LinearNAChemically synthesizedNANANABMECNANANANANANA NA Permeability NA NA NA Permeability coefficient 0.000051 cm/s Direct iodination 12226841
b3pdb_1076Guanidino-MorphiceptGuan-YPFP-NH2Guan-Tyr-Pro-Phe-Pro-NH2NANANA4LinearNAChemically synthesizedNANANAShake FlaskNANANANANANA NA NA NA NA NA Log D -0.3979 Direct iodination 12226841
b3pdb_1077Guanidino-MorphiceptGuan-YPFP-NH2Guan-Tyr-Pro-Phe-Pro-NH2NANANA4LinearNAChemically synthesizedNANANABMECNANANANANANA NA Permeability NA NA NA Unidirectonal influx rate constant 0.0174 mL/(g x min) Direct iodination 12226841
b3pdb_1078Guanidino-MorphiceptGuan-YPFP-NH2Guan-Tyr-Pro-Phe-Pro-NH2NANANA4LinearNAChemically synthesizedNANANABMECNANANANANANA NA Permeability NA NA NA Initial distribution Initial distribution Initial distribution Initial distribution Initial distribu 2.31 ml/g Direct iodination 12226841
b3pdb_1079Guanidino-MorphiceptGuan-YPFP-NH2Guan-Tyr-Pro-Phe-Pro-NH2NANANA4LinearNAChemically synthesizedNANANABMECNANANANANANA NA Permeability NA NA NA Permeability coefficient 0.000067 cm/s Direct iodination 12226841
b3pdb_1084DPLCEY-pen-GFCTyr-D(Pen)-Gly-Phe-CysNANApen2-Cys55LinearNAChemically synthesizedNANANABMECNANANANANANA NA Permeability NA NA NA Permeability coefficient 0.0000939 cm/s NA 8667199
b3pdb_1102OpiorphinQRFSRGln-Arg-Phe-Ser-ArgNANANA5LinearNAChemically synthesizedN[C@@]([H])(CCC(=O)N)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)ONANAInitial concentration in donor chamber-CultureNANANANANANA NA Saturable NA NA NA Parallel artificial membrane permeation assay apparent permiability cofficient 0.00000053 cm/s NA 26143971
b3pdb_1103des-Tyrosine1-D-PhenPFPGPro-D-Phe-Pro-GlyNANANA4LinearNAChemically synthesizedN1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N1[C@@]([H])(CCC1)C(=O)NCC(=O)ONANAInitial concentration in donor chamber-CultureNANANANANANA NA non saturable NA NA NA Permeability index 18 (x 10-4) cm/min H3/C14 1620656
b3pdb_1106PhrANTH2SKDYNSer-Lys-Asp-Tyr-AsnNANANA5LinearNAChemically synthesizedNANANAEfflux study ICUNANANANANANA NA Permeability NA NA NA Brain elemination rate constant -0.05 min-1 Direct iodination 26536593
b3pdb_1107PhrANTH2SKDYNSer-Lys-Asp-Tyr-AsnNANANA5LinearNAChemically synthesizedNANANACapillary depletionNANANANANANA NA NA NA NA NA % parenchyma 79.40% Direct iodination 26536593
b3pdb_1108PhrANTH2SKDYNSer-Lys-Asp-Tyr-AsnNANANA5LinearNAChemically synthesizedNANANACapillary depletionNANANANANANA NA NA NA NA NA % capillary 20.60% Direct iodination 26536593
b3pdb_1109PhrANTH2SKDYNSer-Lys-Asp-Tyr-AsnNANANA5LinearNAChemically synthesizedNANANANANANANAIntravenous NANA NA Permeability NA NA NA Unidirectional influx rate constant 0.00018 mL/(g x min) Direct iodination 26536593
b3pdb_1110PhrANTH2SKDYNSer-Lys-Asp-Tyr-AsnNANANA5LinearNAChemically synthesizedNANANANANANANAIntravenous NANA NA Permeability NA NA NA Initial disrobution volume 0.00659 ml/g Direct iodination 26536593
b3pdb_1161GPEGPEGly-Pro-GluNANANA3LinearNAviralNANANANANANANANANANA NA Permeability NA NA NA Ccsf 9.21 ng/ml NA 15752541
b3pdb_1162MEL-N1606H-Dmt-D-NMeAW-(2-furyl)Map-NH2H-Dmt-D-NMeAla-Trp-(2-furyl)Map-NH2NANANA2LinearNAviralNANANAanti-nociceptionNANANANANANA NA Permeability NA NA NA ED50 0.382 mg/kg NA 28732166
b3pdb_1163MEL-N1608H-Dmt-D-NMeAF-(2-furyl)Map-NH2H-Dmt-D-NMeAla-Phe-(2-furyl)Map-NH2NANANA2LinearNAhumanNANANAanti-nociceptionNANANANANANA NA Permeability NA NA NA ED50 0.489 mg/kg NA 28732166
b3pdb_1164MEL1201H-YPW-(Ph)Map-NH2H-Tyr-Pro-Trp-(Ph)Map-NH2NANANA3LinearNAChemically synthesizedNANANAanti-nociceptionNANANANANANA NA Permeability NA NA NA ED50 5.32 mg/kg NA 26116761
b3pdb_1165MEL1209H-YPW-(3-ClPh)Map-NH2H-Tyr-Pro-Trp-(3-ClPh)Map-NH2NANANA3LinearNAChemically synthesizedNANANAanti-nociceptionNANANANANANA NA Permeability NA NA NA ED50 28.58 mg/kg NA 26116761
b3pdb_1166MEL1214H-YPW-(2-furyl)Map-NH2H-Tyr-Pro-Trp-(2-furyl)Map-NH2NANANA3LinearNAChemically synthesizedNANANAanti-nociceptionNANANANANANA NA Permeability NA NA NA ED50 3.14 mg/kg NA 26116761
b3pdb_1167MEL1224H-YPW-(2-furyl)Map-NH2H-Tyr-Pro-Trp-(3-furyl)Map-NH2NANANA3LinearNAChemically synthesizedNANANAanti-nociceptionNANANANANANA NA Permeability NA NA NA ED50 4.02 mg/kg NA 26116761
b3pdb_1169C-36cKFFDDmt-c[D-Lys-Phe-Phe-Asp]NH2NANANA4LinearNAChemically synthesizedNANANANANANANANANANA NA NA NA NA NA NA NA NA NA
b3pdb_1170F-81NADmt-c[D-Lys-Phe-p-CF3-Phe-Asp]NH2NANANA4LinearNAChemically synthesizedNANANANANANANANANANA NA NA NA NA NA NA NA NA NA
b3pdb_1191Gly-ProGPGly-ProNANANA2LinearNAChemically synthesizedNANANANANANANAin situ brain perfusionNANA NA Permeability NA NA NA Unidirectional flux rate constant 0.00349 mL/(g x min) NA 30962462
b3pdb_1192Gly-ProGPGly-ProNANANA2LinearNAChemically synthesizedNANANANANANANAin situ brain perfusionNANA NA Permeability NA NA NA Brain/perfusate ratio 10.9 NA 30962462
b3pdb_1193Tyr-ProTPTyr-ProNANANA2LinearNAChemically synthesizedNANANANANANANAin situ brain perfusionNANA NA Permeability NA NA NA Unidirectional flux rate constant 0.00353 mL/(g x min) NA 30962462
b3pdb_1194Tyr-ProTPTyr-ProNANANA2LinearNAChemically synthesizedNANANANANANANAin situ brain perfusionNANA NA Permeability NA NA NA Brain/perfusate ratio 10.5 NA 30962462
b3pdb_1204PEP inhibitory peptiPPLPro-Pro-LeuNANANA3LinearNAChemically synthesizedNANANANANANANAIntravenous NANA NA Permeability NA NA NA Unidirectional influx rate constant 0.0003 mL/(g x min) H3/C14 29966196
b3pdb_1219CGKRK-PEG-DSPECGKRKNANANANA5NANAChemically synthesizedNAU87MG cellsNAFluorescent microscopyIt exhibited enhanced transportationMiceNAIntravenous Fluorescence imaging analysisIt penetrated across the BBB to accumulate at tumor sites with the assistance of Bor and active glio CGKRK-PSNPs combined with borneol could improve the anti-glioma efficacy with the prolonged medium s Transcytosis NA Combined with borneol Glioblastoma NA NA NA 32425792
b3pdb_1221MKPMKPMet-Lys-ProNANANA3LinearNACaseinNANANANANAHuman50 μgOral Alzheimer’s Disease Assessment ScaleIt is casein- derived angiotensin-converting enzyme inhibitory peptide with the potential to cross t The safety of daily MKP intake and its potential to improve orientation in adults without dementia. NA NA NA NA NA NA NA 32546992