Year : 2002

Total records found: 2

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AptBacDB_ID ⇅	PMID/DOI ⇅	Year ⇅	Title ⇅	Aptamer name ⇅	Sequence (5′ to 3′) ⇅	Length ⇅	Library ⇅	Type ⇅	Target Organism ⇅	Target ⇅	Objective/Mechanism ⇅	Outcome/Inhibitory effect ⇅	No. of selection round SELEX ⇅	Determination of affinity method ⇅	Kd value ⇅	Activity Role ⇅	Method ⇅	Modification ⇅	Cytotoxicity (cell viability) ⇅	Stability⇅	Potential Candidate ⇅	Half-life ⇅	Patent ⇅
ABdb_1952	11808691	2002	Use of magnetic beads in selection and detection of biotoxin aptamers by electrochemiluminescence and enzymatic methods	Anti-cholera whole toxin aptamers	N/A	N/A	5'-CCGGATCCGTTGATA-N20-GTGGTGTTGGCTCCC-3'	ssDNA	Vibrio Cholerae	Cholera toxin	Developed an aptamer-based electrochemiluminescence assay using a dsDNA aptamer for biotoxin detection.	Detection limit of less than 40 ng in the cholera electrochemiluminescence assay.	5	N/A	N/A	Biosensor	Magnetic Bead (MB)-based SELEX	5'-Biotinylated (for ECL) or 5'-Amidation (NH₂-(CH2)6) (for colorimetric assays)	N/A	N/A	N/A	N/A	N/A
ABdb_1953	11808691	2002	Use of magnetic beads in selection and detection of biotoxin aptamers by electrochemiluminescence and enzymatic methods	Anti-staphylococcal enterotoxin B (SEB) aptamers	N/A	N/A	5'-CCGGATCCGTTGATA-N20-GTGGTGTTGGCTCCC-3'	ssDNA	Staphylococcus aureus (S. aureus)	Staphylococcal Enterotoxin B (SEB)	Developed an aptamer-based electrochemiluminescence assay using a dsDNA aptamer for biotoxin detection.	Detection limit of less than 10 pg SEB with electrochemiluminescence assay.	5	N/A	N/A	Biosensor	Magnetic Bead (MB)-based SELEX	5'-Biotinylated (for ECL) or 5'-Amidation (NH₂-(CH2)6) (for colorimetric assays)	N/A	N/A	N/A	N/A	N/A