AptBacterialDB

Target Organism : Streptococcus Suis

Total records found: 3

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AptBacDB_ID ⇅ PMID/DOI ⇅ Year ⇅ Title ⇅ Aptamer name ⇅ Sequence (5′ to 3′) ⇅ Length ⇅ Library ⇅ Type ⇅ Target Organism ⇅ Target ⇅ Objective/Mechanism ⇅ Outcome/Inhibitory effect ⇅ No. of selection round SELEX ⇅ Determination of affinity method ⇅ Kd value ⇅ Activity Role ⇅ Method ⇅ Modification ⇅ Cytotoxicity (cell viability) ⇅ Stability⇅ Potential Candidate ⇅ Half-life ⇅ Patent ⇅
ABdb_1608 357450142022The Ability of Nuclease-Resistant RNA Aptamer against Streptococcus suis Serotype 2, Strain P1/7 to Reduce Biofilm Formation In VitroR8-su12GGGAGUCGACCGACCAGAA-CAUACUGAGUAAGAUCGGAAAUUUCGGUGUAAGGCCACGG-UAUGUGCGUCUACAUCUAGACUCAU845'-AGTAATACGACTCACTATAGGGAGTCGACCGACCAGAA-N40-TATGTGCGTCTACATCTAGACTCAT-3'ssRNAStreptococcus Suis serotype 2, strain P1/7Whole cellIdentify aptamers that inhibit the biofilm formation of the S. suis target strain.Significantly reduced biofilm formation by 61.2%.8Real-Time Quantitative Polymerase Chain Reaction (RT-qPCR)N/ATherapeuticsWhole Cell-SELEX2'-Fluoro pyrimidines (2'-F-RNA)N/AN/ABest CandidateN/AN/A
ABdb_1609 357450142022The Ability of Nuclease-Resistant RNA Aptamer against Streptococcus suis Serotype 2, Strain P1/7 to Reduce Biofilm Formation In VitroR8-su057GGGAGUCGACCGACCAGAA-UGGAUGUAUGGAACUUGCAGAUCUUAACUGCACGAAGCGU-UAUGUGCGUCUACAUCUAGACUCAU845'-AGTAATACGACTCACTATAGGGAGTCGACCGACCAGAA-N40-TATGTGCGTCTACATCTAGACTCAT-3'ssRNAStreptococcus Suis serotype 2, strain P1/7Whole cellIdentify aptamers that inhibit the biofilm formation of the S. suis target strain.N/A8Real-Time Quantitative Polymerase Chain Reaction (RT-qPCR)N/ATherapeuticsWhole Cell-SELEX2'-Fluoro pyrimidines (2'-F-RNA)N/AN/AN/AN/AN/A
ABdb_1610 357450142022The Ability of Nuclease-Resistant RNA Aptamer against Streptococcus suis Serotype 2, Strain P1/7 to Reduce Biofilm Formation In VitroR8-su15GGGAGUCGACCGACCAGAA-ACACGUUGCUGAAACAUACCGAGUAACAUAAAGCGGGUG-UAUGUGCGUCUACAUCUAGACUCAU835'-AGTAATACGACTCACTATAGGGAGTCGACCGACCAGAA-N40-TATGTGCGTCTACATCTAGACTCAT-3'ssRNAStreptococcus Suis serotype 2, strain P1/7Whole cellIdentify aptamers that inhibit the biofilm formation of the S. suis target strain.N/A8Real-Time Quantitative Polymerase Chain Reaction (RT-qPCR)N/ATherapeuticsWhole Cell-SELEX2'-Fluoro pyrimidines (2'-F-RNA)N/AN/AN/AN/AN/A