Target Organism : Streptococcus Oralis

Total records found: 9

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AptBacDB_ID ⇅	PMID/DOI ⇅	Year ⇅	Title ⇅	Aptamer name ⇅	Sequence (5′ to 3′) ⇅	Length ⇅	Library ⇅	Type ⇅	Target Organism ⇅	Target ⇅	Objective/Mechanism ⇅	Outcome/Inhibitory effect ⇅	No. of selection round SELEX ⇅	Determination of affinity method ⇅	Kd value ⇅	Activity Role ⇅	Method ⇅	Modification ⇅	Cytotoxicity (cell viability) ⇅	Stability⇅	Potential Candidate ⇅	Half-life ⇅	Patent ⇅
ABdb_0609	25269812	2015	Screening and development of DNA aptamers specific to several oral pathogens	ASO-1	CGGATCCATGGGCACTATTTATATCAA-CCTCACATAGTGACGATGTGGTTTGGTACCTCTATGCAA-AATGTCGTTGGTGGCCC	83	5'-CGGATCCATGGGCACTATTTATATCAA-N40-AATGTCGTTGGTGGCCC-3'	ssDNA	Streptococcus Oralis (ATCC 10557)	Whole cell	Screen and develop aptamers specific to oral pathogens.	ASO showed selective binding to S.oralis cell lysates without cross-reaction to the cell lysates of P. gingivalis or T. denticola.	N/A	Modified Western Blot Assay	N/A	Detection	Whole Cell-SELEX	DIG (Digoxigenin) Labeled	N/A	N/A	N/A	N/A	N/A
ABdb_0610	25269812	2015	Screening and development of DNA aptamers specific to several oral pathogens	ASO-2	CGGATCCATGGGCACTATTTATATCAA-CCGTGGATGTACGAAATTAACCGCACACCTAGCTACCAA-AATGTCGTTGGTGGCCC	83	5'-CGGATCCATGGGCACTATTTATATCAA-N40-AATGTCGTTGGTGGCCC-3'	ssDNA	Streptococcus Oralis (ATCC 10557)	Whole cell	Screen and develop aptamers specific to oral pathogens.	ASO showed selective binding to S.oralis cell lysates without cross-reaction to the cell lysates of P. gingivalis or T. denticola.	N/A	Modified Western Blot Assay	N/A	Detection	Whole Cell-SELEX	DIG (Digoxigenin) Labeled	N/A	N/A	N/A	N/A	N/A
ABdb_0611	25269812	2015	Screening and development of DNA aptamers specific to several oral pathogens	ASO-3	CGGATCCATGGGCACTATTTATATCAA-CGCATGCTTCTCGGGATACGGGCGGCTCGATAGAGTCAA-AATGTCGTTGGTGGCCC	83	5'-CGGATCCATGGGCACTATTTATATCAA-N40-AATGTCGTTGGTGGCCC-3'	ssDNA	Streptococcus Oralis (ATCC 10557)	Whole cell	Screen and develop aptamers specific to oral pathogens.	ASO showed selective binding to S.oralis cell lysates without cross-reaction to the cell lysates of P. gingivalis or T. denticola.	N/A	Modified Western Blot Assay	N/A	Detection	Whole Cell-SELEX	DIG (Digoxigenin) Labeled	N/A	N/A	N/A	N/A	N/A
ABdb_0612	25269812	2015	Screening and development of DNA aptamers specific to several oral pathogens	ASO-4	CGGATCCATGGGCACTATTTATATCAA-GCTTACTACGTTTGCCTCAGTGTGTTCCGGTCTTAACAA-AATGTCGTTGGTGGCCC	83	5'-CGGATCCATGGGCACTATTTATATCAA-N40-AATGTCGTTGGTGGCCC-3'	ssDNA	Streptococcus Oralis (ATCC 10557)	Whole cell	Screen and develop aptamers specific to oral pathogens.	ASO showed selective binding to S.oralis cell lysates without cross-reaction to the cell lysates of P. gingivalis or T. denticola.	N/A	Modified Western Blot Assay	N/A	Detection	Whole Cell-SELEX	DIG (Digoxigenin) Labeled	N/A	N/A	N/A	N/A	N/A
ABdb_0613	25269812	2015	Screening and development of DNA aptamers specific to several oral pathogens	ASO-5	CGGATCCATGGGCACTATTTATATCAA-CCCATACCTTTTTCGATAGTAAGTGCCATGCCCATCTAA-AATGTCGTTGGTGGCCC	83	5'-CGGATCCATGGGCACTATTTATATCAA-N40-AATGTCGTTGGTGGCCC-3'	ssDNA	Streptococcus Oralis (ATCC 10557)	Whole cell	Screen and develop aptamers specific to oral pathogens.	ASO showed selective binding to S.oralis cell lysates without cross-reaction to the cell lysates of P. gingivalis or T. denticola.	N/A	Modified Western Blot Assay	N/A	Detection	Whole Cell-SELEX	DIG (Digoxigenin) Labeled	N/A	N/A	N/A	N/A	N/A
ABdb_0614	25269812	2015	Screening and development of DNA aptamers specific to several oral pathogens	ASO-6	CGGATCCATGGGCACTATTTATATCAA-GCCTAGAACCCCCTGTCTAGTCAAGTAGTGCGAGTGCAA-AATGTCGTTGGTGGCCC	83	5'-CGGATCCATGGGCACTATTTATATCAA-N40-AATGTCGTTGGTGGCCC-3'	ssDNA	Streptococcus Oralis (ATCC 10557)	Whole cell	Screen and develop aptamers specific to oral pathogens.	ASO showed selective binding to S.oralis cell lysates without cross-reaction to the cell lysates of P. gingivalis or T. denticola.	N/A	Modified Western Blot Assay	N/A	Detection	Whole Cell-SELEX	DIG (Digoxigenin) Labeled	N/A	N/A	N/A	N/A	N/A
ABdb_0615	25269812	2015	Screening and development of DNA aptamers specific to several oral pathogens	ASO-7	CGGATCCATGGGCACTATTTATATCAA-GCCTTACCGCTCTATCACTCGTCTGTTGCCACTCAGTAA-AATGTCGTTGGTGGCCC	83	5'-CGGATCCATGGGCACTATTTATATCAA-N40-AATGTCGTTGGTGGCCC-3'	ssDNA	Streptococcus Oralis (ATCC 10557)	Whole cell	Screen and develop aptamers specific to oral pathogens.	ASO showed selective binding to S.oralis cell lysates without cross-reaction to the cell lysates of P. gingivalis or T. denticola.	N/A	Modified Western Blot Assay	N/A	Detection	Whole Cell-SELEX	DIG (Digoxigenin) Labeled	N/A	N/A	N/A	N/A	N/A
ABdb_0616	25269812	2015	Screening and development of DNA aptamers specific to several oral pathogens	ASO-8	CGGATCCATGGGCACTATTTATATCAA-TGCGCCGATAGTTTCGATCATGATGCATCTGGCTGTCAA-AATGTCGTTGGTGGCCC	83	5'-CGGATCCATGGGCACTATTTATATCAA-N40-AATGTCGTTGGTGGCCC-3'	ssDNA	Streptococcus Oralis (ATCC 10557)	Whole cell	Screen and develop aptamers specific to oral pathogens.	ASO showed selective binding to S.oralis cell lysates without cross-reaction to the cell lysates of P. gingivalis or T. denticola.	N/A	Modified Western Blot Assay	N/A	Detection	Whole Cell-SELEX	DIG (Digoxigenin) Labeled	N/A	N/A	N/A	N/A	N/A
ABdb_0617	25269812	2015	Screening and development of DNA aptamers specific to several oral pathogens	ASO-9	CGGATCCATGGGCACTATTTATATCAA-CGGTAGTACTACTGGAGACAACTTCGCATACTTTAGTAA-AATGTCGTTGGTGGCCC	83	5'-CGGATCCATGGGCACTATTTATATCAA-N40-AATGTCGTTGGTGGCCC-3'	ssDNA	Streptococcus Oralis (ATCC 10557)	Whole cell	Screen and develop aptamers specific to oral pathogens.	ASO showed selective binding to S.oralis cell lysates without cross-reaction to the cell lysates of P. gingivalis or T. denticola.	N/A	Modified Western Blot Assay	N/A	Detection	Whole Cell-SELEX	DIG (Digoxigenin) Labeled	N/A	N/A	N/A	N/A	N/A