Target Organism : Streptococcus Agalactiae

Total records found: 6

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AptBacDB_ID ⇅	PMID/DOI ⇅	Year ⇅	Title ⇅	Aptamer name ⇅	Sequence (5′ to 3′) ⇅	Length ⇅	Library ⇅	Type ⇅	Target Organism ⇅	Target ⇅	Objective/Mechanism ⇅	Outcome/Inhibitory effect ⇅	No. of selection round SELEX ⇅	Determination of affinity method ⇅	Kd value ⇅	Activity Role ⇅	Method ⇅	Modification ⇅	Cytotoxicity (cell viability) ⇅	Stability⇅	Potential Candidate ⇅	Half-life ⇅	Patent ⇅
ABdb_1692	35776386	2022	A sequential toggle cell-SELEX DNA aptamer for targeting Staphylococcus aureus, Streptococcus agalactiae, and Escherichia coli bacteria	S15K3	CCGGAATTCCTAATACGACTC-CCAGCAGCAAGGTGCGGTACCCGGGGATGCGGGCTTGCTG-TATTGAAAACGCGGCCGCGG	81	5'-CCGGAATTCCTAATACGACTC-N40-TATTGAAAACGCGGCCGCGG-3'	ssDNA	Streptococcus Agalactiae	Whole cell	Isolate polyclonal DNA aptamer with broad reactivity to the mastitis bacteria S. aureus, S. agalactiae, and E. coli.	S15K3 and S15K13 have a high binding affinity for S. agalactiae.	15	Real-Time Quantitative Polymerase Chain Reaction (RT-qPCR)	6,84 nM	Detection	Sequential Toggle Cell-SELEX (STC-SELEX)	N/A	N/A	N/A	Best Candidate	N/A	N/A
ABdb_1693	35776386	2022	A sequential toggle cell-SELEX DNA aptamer for targeting Staphylococcus aureus, Streptococcus agalactiae, and Escherichia coli bacteria	S15K4	CCGGAATTCCTAATACGACTC-CCCGGGCCCACAGGGTACGCGTCTGCGGCTGGCCGGTCCC-TATTGAAAACGCGGCCGCGG	81	5'-CCGGAATTCCTAATACGACTC-N40-TATTGAAAACGCGGCCGCGG-3'	ssDNA	Streptococcus Agalactiae	Whole cell	Isolate polyclonal DNA aptamer with broad reactivity to the mastitis bacteria S. aureus, S. agalactiae, and E. coli.	N/A	15	Real-Time Quantitative Polymerase Chain Reaction (RT-qPCR)	N/A	Detection	Sequential Toggle Cell-SELEX (STC-SELEX)	N/A	N/A	N/A	N/A	N/A	N/A
ABdb_1694	35776386	2022	A sequential toggle cell-SELEX DNA aptamer for targeting Staphylococcus aureus, Streptococcus agalactiae, and Escherichia coli bacteria	S15K6	CCGGAATTCCTAATACGACTC-GCGGGACGGGGAGTGCGCTGGGCATGTGGGCGCCGGGGGA-TATTGAAAACGCGGCCGCGG	81	5'-CCGGAATTCCTAATACGACTC-N40-TATTGAAAACGCGGCCGCGG-3'	ssDNA	Streptococcus Agalactiae	Whole cell	Isolate polyclonal DNA aptamer with broad reactivity to the mastitis bacteria S. aureus, S. agalactiae, and E. coli.	N/A	15	Real-Time Quantitative Polymerase Chain Reaction (RT-qPCR)	20,79 nM	Detection	Sequential Toggle Cell-SELEX (STC-SELEX)	N/A	N/A	N/A	N/A	N/A	N/A
ABdb_1695	35776386	2022	A sequential toggle cell-SELEX DNA aptamer for targeting Staphylococcus aureus, Streptococcus agalactiae, and Escherichia coli bacteria	S15K13	CCGGAATTCCTAATACGACTC-CACGCGCAGGCAGCCACCGACCAGGTGCTCGTATGGTTGG-TATTGAAAACGCGGCCGCGG	81	5'-CCGGAATTCCTAATACGACTC-N40-TATTGAAAACGCGGCCGCGG-3'	ssDNA	Streptococcus Agalactiae	Whole cell	Isolate polyclonal DNA aptamer with broad reactivity to the mastitis bacteria S. aureus, S. agalactiae, and E. coli.	S15K3 and S15K13 have a high binding affinity for S. agalactiae.	15	Real-Time Quantitative Polymerase Chain Reaction (RT-qPCR)	6,53 nM	Detection	Sequential Toggle Cell-SELEX (STC-SELEX)	N/A	N/A	N/A	Best Candidate	N/A	N/A
ABdb_1696	35776386	2022	A sequential toggle cell-SELEX DNA aptamer for targeting Staphylococcus aureus, Streptococcus agalactiae, and Escherichia coli bacteria	S15K15	CCGGAATTCCTAATACGACTC-CAGGACAGTACTCTGGACGGCAATACGTATATACGTACGG-TATTGAAAACGCGGCCGCGG	81	5'-CCGGAATTCCTAATACGACTC-N40-TATTGAAAACGCGGCCGCGG-3'	ssDNA	Streptococcus Agalactiae	Whole cell	Isolate polyclonal DNA aptamer with broad reactivity to the mastitis bacteria S. aureus, S. agalactiae, and E. coli.	N/A	15	Real-Time Quantitative Polymerase Chain Reaction (RT-qPCR)	45,36 nM	Detection	Sequential Toggle Cell-SELEX (STC-SELEX)	N/A	N/A	N/A	N/A	N/A	N/A
ABdb_1697	35776386	2022	A sequential toggle cell-SELEX DNA aptamer for targeting Staphylococcus aureus, Streptococcus agalactiae, and Escherichia coli bacteria	S15K20	CCGGAATTCCTAATACGACTC-CCGGCGCCACGACATGGGCGCTGCCGGTGTGGTCGCGGGA-TATTGAAAACGCGGCCGCGG	81	5'-CCGGAATTCCTAATACGACTC-N40-TATTGAAAACGCGGCCGCGG-3'	ssDNA	Streptococcus Agalactiae	Whole cell	Isolate polyclonal DNA aptamer with broad reactivity to the mastitis bacteria S. aureus, S. agalactiae, and E. coli.	N/A	15	Real-Time Quantitative Polymerase Chain Reaction (RT-qPCR)	N/A	Detection	Sequential Toggle Cell-SELEX (STC-SELEX)	N/A	N/A	N/A	N/A	N/A	N/A