AptBacterialDB

Target Organism : Staphylococcus Epidermidis

Total records found: 20

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AptBacDB_ID ⇅ PMID/DOI ⇅ Year ⇅ Title ⇅ Aptamer name ⇅ Sequence (5′ to 3′) ⇅ Length ⇅ Library ⇅ Type ⇅ Target Organism ⇅ Target ⇅ Objective/Mechanism ⇅ Outcome/Inhibitory effect ⇅ No. of selection round SELEX ⇅ Determination of affinity method ⇅ Kd value ⇅ Activity Role ⇅ Method ⇅ Modification ⇅ Cytotoxicity (cell viability) ⇅ Stability⇅ Potential Candidate ⇅ Half-life ⇅ Patent ⇅
ABdb_0982 282725542017Broadly reactive aptamers targeting bacteria belonging to different genera using a sequential toggle cell-SELEXSTC-01CATATCCGCGTCGCTGCGCTCAGACCCACCACTACGCACC405'-CGTACGGAATTCGCTAGC-N40-GGATCCGAGCTCCACGTG-3'ssDNAEscherichia Coli (E. Coli) (KCTC 2571), Enterobacter aerogenes (E. aerogenes) (KCTC 2190), Klebsiella pneumoniae (K. pneumoniae) (KCTC 2208), Citrobacter freundii (C. freundii) (KCTC 2006), Bacillus Subtilis (B. Subtilis) (KCTC 1022), and Staphylococcus Epidermidis (S. Epidermidis) (KCTC 1917)Whole cellIdentify aptamers with broad affinity for bacteria across different genera.N/A18N/AN/ADetectionSequential Toggle Cell-SELEX (STC-SELEX)3'-FAM LabeledN/AN/AN/AN/AN/A
ABdb_0983 282725542017Broadly reactive aptamers targeting bacteria belonging to different genera using a sequential toggle cell-SELEXSTC-02CATATCCGTGTCGCTGCGCTCAGACCCACCACCACGCACC405'-CGTACGGAATTCGCTAGC-N40-GGATCCGAGCTCCACGTG-3'ssDNAEscherichia Coli (E. Coli) (KCTC 2571), Enterobacter aerogenes (E. aerogenes) (KCTC 2190), Klebsiella pneumoniae (K. pneumoniae) (KCTC 2208), Citrobacter freundii (C. freundii) (KCTC 2006), Bacillus Subtilis (B. Subtilis) (KCTC 1022), and Staphylococcus Epidermidis (S. Epidermidis) (KCTC 1917)Whole cellIdentify aptamers with broad affinity for bacteria across different genera.N/A18N/AN/ADetectionSequential Toggle Cell-SELEX (STC-SELEX)3'-FAM LabeledN/AN/AN/AN/AN/A
ABdb_0984 282725542017Broadly reactive aptamers targeting bacteria belonging to different genera using a sequential toggle cell-SELEXSTC-03CATATCCGCGTCGCTGCGCTCAGACCCACCACCACGCACC405'-CGTACGGAATTCGCTAGC-N40-GGATCCGAGCTCCACGTG-3'ssDNAEscherichia Coli (E. Coli) (KCTC 2571), Enterobacter aerogenes (E. aerogenes) (KCTC 2190), Klebsiella pneumoniae (K. pneumoniae) (KCTC 2208), Citrobacter freundii (C. freundii) (KCTC 2006), Bacillus Subtilis (B. Subtilis) (KCTC 1022), and Staphylococcus Epidermidis (S. Epidermidis) (KCTC 1917)Whole cellIdentify aptamers with broad affinity for bacteria across different genera.STC-03 showed better affinity to E. aerogenes, K. pneumoniae, C. freundii, and B. subtilis.18Micro-Fluorospectrophotometer (Fluorescence Spectroscopy)27.2 nM (for E. coli), 11.9 nM (for E. aerogenes), 9.22 nM (for K. pneumoniae), 15.9 nM (for C. freundii), 9.97 nM (for B. subtilis), and 16.4 nM (for S. epidermidis)DetectionSequential Toggle Cell-SELEX (STC-SELEX)3'-FAM LabeledN/AN/ABest CandidateN/AN/A
ABdb_0985 282725542017Broadly reactive aptamers targeting bacteria belonging to different genera using a sequential toggle cell-SELEXSTC-04ATATCCGCGTCGCTGCGCTCAGACCCACCACCACGCACC395'-CGTACGGAATTCGCTAGC-N40-GGATCCGAGCTCCACGTG-3'ssDNAEscherichia Coli (E. Coli) (KCTC 2571), Enterobacter aerogenes (E. aerogenes) (KCTC 2190), Klebsiella pneumoniae (K. pneumoniae) (KCTC 2208), Citrobacter freundii (C. freundii) (KCTC 2006), Bacillus Subtilis (B. Subtilis) (KCTC 1022), and Staphylococcus Epidermidis (S. Epidermidis) (KCTC 1917)Whole cellIdentify aptamers with broad affinity for bacteria across different genera.N/A18N/AN/ADetectionSequential Toggle Cell-SELEX (STC-SELEX)3'-FAM LabeledN/AN/AN/AN/AN/A
ABdb_0986 282725542017Broadly reactive aptamers targeting bacteria belonging to different genera using a sequential toggle cell-SELEXSTC-05CATATCCGCGTCGCTGCGCTCAGACCCACCACCCGCCC385'-CGTACGGAATTCGCTAGC-N40-GGATCCGAGCTCCACGTG-3'ssDNAEscherichia Coli (E. Coli) (KCTC 2571), Enterobacter aerogenes (E. aerogenes) (KCTC 2190), Klebsiella pneumoniae (K. pneumoniae) (KCTC 2208), Citrobacter freundii (C. freundii) (KCTC 2006), Bacillus Subtilis (B. Subtilis) (KCTC 1022), and Staphylococcus Epidermidis (S. Epidermidis) (KCTC 1917)Whole cellIdentify aptamers with broad affinity for bacteria across different genera.N/A18N/AN/ADetectionSequential Toggle Cell-SELEX (STC-SELEX)3'-FAM LabeledN/AN/AN/AN/AN/A
ABdb_0987 282725542017Broadly reactive aptamers targeting bacteria belonging to different genera using a sequential toggle cell-SELEXSTC-06GGGCGGGGGTGCTGGGGGAATGGAGTGCTGCGTGCTGCGG405'-CGTACGGAATTCGCTAGC-N40-GGATCCGAGCTCCACGTG-3'ssDNAEscherichia Coli (E. Coli) (KCTC 2571), Enterobacter aerogenes (E. aerogenes) (KCTC 2190), Klebsiella pneumoniae (K. pneumoniae) (KCTC 2208), Citrobacter freundii (C. freundii) (KCTC 2006), Bacillus Subtilis (B. Subtilis) (KCTC 1022), and Staphylococcus Epidermidis (S. Epidermidis) (KCTC 1917)Whole cellIdentify aptamers with broad affinity for bacteria across different genera.N/A18N/AN/ADetectionSequential Toggle Cell-SELEX (STC-SELEX)3'-FAM LabeledN/AN/AN/AN/AN/A
ABdb_0988 282725542017Broadly reactive aptamers targeting bacteria belonging to different genera using a sequential toggle cell-SELEXSTC-07GGGCGGGGGGTGCTGGGGGAATGGAGTGCTGCGTGCTGCG405'-CGTACGGAATTCGCTAGC-N40-GGATCCGAGCTCCACGTG-3'ssDNAEscherichia Coli (E. Coli) (KCTC 2571), Enterobacter aerogenes (E. aerogenes) (KCTC 2190), Klebsiella pneumoniae (K. pneumoniae) (KCTC 2208), Citrobacter freundii (C. freundii) (KCTC 2006), Bacillus Subtilis (B. Subtilis) (KCTC 1022), and Staphylococcus Epidermidis (S. Epidermidis) (KCTC 1917)Whole cellIdentify aptamers with broad affinity for bacteria across different genera.N/A18N/AN/ADetectionSequential Toggle Cell-SELEX (STC-SELEX)3'-FAM LabeledN/AN/AN/AN/AN/A
ABdb_0989 282725542017Broadly reactive aptamers targeting bacteria belonging to different genera using a sequential toggle cell-SELEXSTC-08GGGCGGGGGTGCTGGGAGAATGGAGTGCTGCGTGCTGCAG405'-CGTACGGAATTCGCTAGC-N40-GGATCCGAGCTCCACGTG-3'ssDNAEscherichia Coli (E. Coli) (KCTC 2571), Enterobacter aerogenes (E. aerogenes) (KCTC 2190), Klebsiella pneumoniae (K. pneumoniae) (KCTC 2208), Citrobacter freundii (C. freundii) (KCTC 2006), Bacillus Subtilis (B. Subtilis) (KCTC 1022), and Staphylococcus Epidermidis (S. Epidermidis) (KCTC 1917)Whole cellIdentify aptamers with broad affinity for bacteria across different genera.N/A18N/AN/ADetectionSequential Toggle Cell-SELEX (STC-SELEX)3'-FAM LabeledN/AN/AN/AN/AN/A
ABdb_0990 282725542017Broadly reactive aptamers targeting bacteria belonging to different genera using a sequential toggle cell-SELEXSTC-09GGGCAGGTGTGCTGGGGGAATGGAGTGCTGCGTGCTGCGG405'-CGTACGGAATTCGCTAGC-N40-GGATCCGAGCTCCACGTG-3'ssDNAEscherichia Coli (E. Coli) (KCTC 2571), Enterobacter aerogenes (E. aerogenes) (KCTC 2190), Klebsiella pneumoniae (K. pneumoniae) (KCTC 2208), Citrobacter freundii (C. freundii) (KCTC 2006), Bacillus Subtilis (B. Subtilis) (KCTC 1022), and Staphylococcus Epidermidis (S. Epidermidis) (KCTC 1917)Whole cellIdentify aptamers with broad affinity for bacteria across different genera.N/A18N/AN/ADetectionSequential Toggle Cell-SELEX (STC-SELEX)3'-FAM LabeledN/AN/AN/AN/AN/A
ABdb_0991 282725542017Broadly reactive aptamers targeting bacteria belonging to different genera using a sequential toggle cell-SELEXSTC-10AGACCGCAGGTGCACCGGGCGACGTCTCTGGGTGTGGTGA405'-CGTACGGAATTCGCTAGC-N40-GGATCCGAGCTCCACGTG-3'ssDNAEscherichia Coli (E. Coli) (KCTC 2571), Enterobacter aerogenes (E. aerogenes) (KCTC 2190), Klebsiella pneumoniae (K. pneumoniae) (KCTC 2208), Citrobacter freundii (C. freundii) (KCTC 2006), Bacillus Subtilis (B. Subtilis) (KCTC 1022), and Staphylococcus Epidermidis (S. Epidermidis) (KCTC 1917)Whole cellIdentify aptamers with broad affinity for bacteria across different genera.N/A18N/AN/ADetectionSequential Toggle Cell-SELEX (STC-SELEX)3'-FAM LabeledN/AN/AN/AN/AN/A
ABdb_0992 282725542017Broadly reactive aptamers targeting bacteria belonging to different genera using a sequential toggle cell-SELEXSTC-11AGACCGCAGGTGCACTGGGCGACGTCTCTGGGTGTGGTGT405'-CGTACGGAATTCGCTAGC-N40-GGATCCGAGCTCCACGTG-3'ssDNAEscherichia Coli (E. Coli) (KCTC 2571), Enterobacter aerogenes (E. aerogenes) (KCTC 2190), Klebsiella pneumoniae (K. pneumoniae) (KCTC 2208), Citrobacter freundii (C. freundii) (KCTC 2006), Bacillus Subtilis (B. Subtilis) (KCTC 1022), and Staphylococcus Epidermidis (S. Epidermidis) (KCTC 1917)Whole cellIdentify aptamers with broad affinity for bacteria across different genera.N/A18N/AN/ADetectionSequential Toggle Cell-SELEX (STC-SELEX)3'-FAM LabeledN/AN/AN/AN/AN/A
ABdb_0993 282725542017Broadly reactive aptamers targeting bacteria belonging to different genera using a sequential toggle cell-SELEXSTC-12GGACCGCAGGTGCACTGGGCGACGTCTCTGGGTGTGGTGT405'-CGTACGGAATTCGCTAGC-N40-GGATCCGAGCTCCACGTG-3'ssDNAEscherichia Coli (E. Coli) (KCTC 2571), Enterobacter aerogenes (E. aerogenes) (KCTC 2190), Klebsiella pneumoniae (K. pneumoniae) (KCTC 2208), Citrobacter freundii (C. freundii) (KCTC 2006), Bacillus Subtilis (B. Subtilis) (KCTC 1022), and Staphylococcus Epidermidis (S. Epidermidis) (KCTC 1917)Whole cellIdentify aptamers with broad affinity for bacteria across different genera.STC-12 showed better affinity to E. coli and S. epidermidis.18Micro-Fluorospectrophotometer (Fluorescence Spectroscopy)38.5 nM (for E. coli), 33.7 nM (for E. aerogenes), 16.3 nM (for K. pneumoniae), 25.6 nM (for C. freundii), 18.9 nM (for B. subtilis), and 13.7 nM (for S. epidermidis)DetectionSequential Toggle Cell-SELEX (STC-SELEX)3'-FAM LabeledN/AN/ABest CandidateN/AN/A
ABdb_0994 282725542017Broadly reactive aptamers targeting bacteria belonging to different genera using a sequential toggle cell-SELEXSTC-13GGACGCGCGTTGGTGGTGGATGGTGTGTTACACGTGTTGT405'-CGTACGGAATTCGCTAGC-N40-GGATCCGAGCTCCACGTG-3'ssDNAEscherichia Coli (E. Coli) (KCTC 2571), Enterobacter aerogenes (E. aerogenes) (KCTC 2190), Klebsiella pneumoniae (K. pneumoniae) (KCTC 2208), Citrobacter freundii (C. freundii) (KCTC 2006), Bacillus Subtilis (B. Subtilis) (KCTC 1022), and Staphylococcus Epidermidis (S. Epidermidis) (KCTC 1917)Whole cellIdentify aptamers with broad affinity for bacteria across different genera.N/A18N/AN/ADetectionSequential Toggle Cell-SELEX (STC-SELEX)3'-FAM LabeledN/AN/AN/AN/AN/A
ABdb_0995 282725542017Broadly reactive aptamers targeting bacteria belonging to different genera using a sequential toggle cell-SELEXSTC-14CGGGGTGGGACCAGTCTTGCGCGGGTGAC295'-CGTACGGAATTCGCTAGC-N40-GGATCCGAGCTCCACGTG-3'ssDNAEscherichia Coli (E. Coli) (KCTC 2571), Enterobacter aerogenes (E. aerogenes) (KCTC 2190), Klebsiella pneumoniae (K. pneumoniae) (KCTC 2208), Citrobacter freundii (C. freundii) (KCTC 2006), Bacillus Subtilis (B. Subtilis) (KCTC 1022), and Staphylococcus Epidermidis (S. Epidermidis) (KCTC 1917)Whole cellIdentify aptamers with broad affinity for bacteria across different genera.N/A18N/AN/ADetectionSequential Toggle Cell-SELEX (STC-SELEX)3'-FAM LabeledN/AN/AN/AN/AN/A
ABdb_0996 282725542017Broadly reactive aptamers targeting bacteria belonging to different genera using a sequential toggle cell-SELEXSTC-15GGACTGGAGTCTAGACCGGGTAGCTGTGGT305'-CGTACGGAATTCGCTAGC-N40-GGATCCGAGCTCCACGTG-3'ssDNAEscherichia Coli (E. Coli) (KCTC 2571), Enterobacter aerogenes (E. aerogenes) (KCTC 2190), Klebsiella pneumoniae (K. pneumoniae) (KCTC 2208), Citrobacter freundii (C. freundii) (KCTC 2006), Bacillus Subtilis (B. Subtilis) (KCTC 1022), and Staphylococcus Epidermidis (S. Epidermidis) (KCTC 1917)Whole cellIdentify aptamers with broad affinity for bacteria across different genera.N/A18N/AN/ADetectionSequential Toggle Cell-SELEX (STC-SELEX)3'-FAM LabeledN/AN/AN/AN/AN/A
ABdb_1061 304773312018Rapid selection of single-stranded DNA aptamers binding Staphylococcus epidermidis in platelet concentratesSE40TACGACTCACTATAGGGATCC-ACCTATGGCAGATTGAGCCCAAGGGCTGTGCAGC-GAATTCCCTTTAGTGAGGGTT765'-TACGACTCACTATAGGGATCC-N34-GAATTCCCTTTAGTGAGGGTT-3'ssDNAStaphylococcus Epidermidis (ATCC 49134)Whole cellIdentify aptamers that capture, detect or remove S. epidermidis contaminant from platelet concentrates.N/A1Colorimetric Peroxidase-Based Aptamer Plate Binding AssayN/ADetectionWhole Cell RIDA5'-BiotinylatedN/AN/AN/AN/AN/A
ABdb_1062 304773312018Rapid selection of single-stranded DNA aptamers binding Staphylococcus epidermidis in platelet concentratesSE42TACGACTCACTATAGGGATCC-CCCCGAGTGAAGAGCAGGACAGCGGGACAGCGTC-GAATTCCCTTTAGTGAGGGTT765'-TACGACTCACTATAGGGATCC-N34-GAATTCCCTTTAGTGAGGGTT-3'ssDNAStaphylococcus Epidermidis (ATCC 49134)Whole cellIdentify aptamers that capture, detect or remove S. epidermidis contaminant from platelet concentrates.N/A1Colorimetric Peroxidase-Based Aptamer Plate Binding AssayN/ADetectionWhole Cell RIDA5'-BiotinylatedN/AN/AN/AN/AN/A
ABdb_1063 304773312018Rapid selection of single-stranded DNA aptamers binding Staphylococcus epidermidis in platelet concentratesSE43TACGACTCACTATAGGGATCC-GTGACTGTACGGGCTCAGTCGTTACTTGAGAGTT-GAATTCCCTTTAGTGAGGGTT765'-TACGACTCACTATAGGGATCC-N34-GAATTCCCTTTAGTGAGGGTT-3'ssDNAStaphylococcus Epidermidis (ATCC 49134)Whole cellIdentify aptamers that capture, detect or remove S. epidermidis contaminant from platelet concentrates.SE43 bound to bacteria was four times higher compared with scrambled control and background controls, and twofold higher in PBS.1Colorimetric Peroxidase-Based Aptamer Plate Binding AssayN/ADetectionWhole Cell RIDA5'-BiotinylatedN/AN/ABest CandidateN/AN/A
ABdb_1064 304773312018Rapid selection of single-stranded DNA aptamers binding Staphylococcus epidermidis in platelet concentratesSE48TACGACTCACTATAGGGATCC-AATGGCACAGCGCCTGGAACGTACTCTGTACCTG-GAATTCCCTTTAGTGAGGGTT765'-TACGACTCACTATAGGGATCC-N34-GAATTCCCTTTAGTGAGGGTT-3'ssDNAStaphylococcus Epidermidis (ATCC 49134)Whole cellIdentify aptamers that capture, detect or remove S. epidermidis contaminant from platelet concentrates.N/A1Colorimetric Peroxidase-Based Aptamer Plate Binding AssayN/ADetectionWhole Cell RIDA5'-BiotinylatedN/AN/AN/AN/AN/A
ABdb_1065 304773312018Rapid selection of single-stranded DNA aptamers binding Staphylococcus epidermidis in platelet concentratesSE52TACGACTCACTATAGGGATCC-TTCGCATCCGGCACGATGGCTAGGACACCCCGAT-GAATTCCCTTTAGTGAGGGTT765'-TACGACTCACTATAGGGATCC-N34-GAATTCCCTTTAGTGAGGGTT-3'ssDNAStaphylococcus Epidermidis (ATCC 49134)Whole cellIdentify aptamers that capture, detect or remove S. epidermidis contaminant from platelet concentrates.N/A1Colorimetric Peroxidase-Based Aptamer Plate Binding AssayN/ADetectionWhole Cell RIDA5'-BiotinylatedN/AN/AN/AN/AN/A