AptBacterialDB

Target Organism : Helicobacter Pylori

Total records found: 27

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AptBacDB_ID ⇅ PMID/DOI ⇅ Year ⇅ Title ⇅ Aptamer name ⇅ Sequence (5′ to 3′) ⇅ Length ⇅ Library ⇅ Type ⇅ Target Organism ⇅ Target ⇅ Objective/Mechanism ⇅ Outcome/Inhibitory effect ⇅ No. of selection round SELEX ⇅ Determination of affinity method ⇅ Kd value ⇅ Activity Role ⇅ Method ⇅ Modification ⇅ Cytotoxicity (cell viability) ⇅ Stability⇅ Potential Candidate ⇅ Half-life ⇅ Patent ⇅
ABdb_1238 309501492019Recognition of Helicobacter pylori by protein-targeting aptamersHp1AGTGTGCTCTTCTCAGGTCT-GTGGCCGGGGGCACTAATGCGGGCTATAAGTCTCCTTGGG-GCAGTGTCTCAGCATACGCA805'-AGTGTGCTCTTCTCAGGTCT-40N-GCAGTGTCTCAGCATACGCA-3'ssDNAHelicobacter PyloriH. pylori surface recombinant antigens (HP-Ag)Identify aptamers against H pylori surface recombinant antigens.N/AN/AFluorescence Binding Assay35.60 ± 6.36 nMDetectionSELEX5'-FAM LabeledN/AN/AN/AN/AN/A
ABdb_1239 309501492019Recognition of Helicobacter pylori by protein-targeting aptamersHp2AGTGTGCTCTTCTCAGGTCT-CCTATACCTGGCATCAGAGAGCTAGGGGCCACGGTTCGCA-GCAGTGTCTCAGCATACGCA805'-AGTGTGCTCTTCTCAGGTCT-40N-GCAGTGTCTCAGCATACGCA-3'ssDNAHelicobacter PyloriH. pylori surface recombinant antigens (HP-Ag)Identify aptamers against H pylori surface recombinant antigens.N/AN/AFluorescence Binding Assay204.38 ± 97.31 nMDetectionSELEX5'-FAM LabeledN/AN/AN/AN/AN/A
ABdb_1240 309501492019Recognition of Helicobacter pylori by protein-targeting aptamersHp3AGTGTGCTCTTCTCAGGTCT-GGTGCTGCGATGCTTTCTGGTGGTGTATGGTTGTCTTTTG-GCAGTGTCTCAGCATACGCA805'-AGTGTGCTCTTCTCAGGTCT-40N-GCAGTGTCTCAGCATACGCA-3'ssDNAHelicobacter PyloriH. pylori surface recombinant antigens (HP-Ag)Identify aptamers against H pylori surface recombinant antigens.N/AN/AFluorescence Binding AssayN/ADetectionSELEX5'-FAM LabeledN/AN/AN/AN/AN/A
ABdb_1241 309501492019Recognition of Helicobacter pylori by protein-targeting aptamersHp4AGTGTGCTCTTCTCAGGTCT-CGGCGCGGTTGTGGGTACCTAGGGTTGTTGTTGCTTCTCA-GCAGTGTCTCAGCATACGCA805'-AGTGTGCTCTTCTCAGGTCT-40N-GCAGTGTCTCAGCATACGCA-3'ssDNAHelicobacter PyloriH. pylori surface recombinant antigens (HP-Ag)Identify aptamers against H pylori surface recombinant antigens.Hp4 had excellent binding to H pylori cells and almost no binding to E coli, S aureus, or V anguillarum.N/AFluorescence Binding Assay26.48 ± 5.72 nMDetectionSELEX5'-FAM LabeledN/AN/ABest CandidateN/AN/A
ABdb_1242 309501492019Recognition of Helicobacter pylori by protein-targeting aptamersHp5AGTGTGCTCTTCTCAGGTCT-GGGCTGTGGGTCGGCACGTCGTCTCTTCATGGTTGTGGTG-GCAGTGTCTCAGCATACGCA805'-AGTGTGCTCTTCTCAGGTCT-40N-GCAGTGTCTCAGCATACGCA-3'ssDNAHelicobacter PyloriH. pylori surface recombinant antigens (HP-Ag)Identify aptamers against H pylori surface recombinant antigens.N/AN/AFluorescence Binding AssayN/ADetectionSELEX5'-FAM LabeledN/AN/AN/AN/AN/A
ABdb_1243 309501492019Recognition of Helicobacter pylori by protein-targeting aptamersHp6AGTGTGCTCTTCTCAGGTCT-TTAGGGACCCATGGGCTAACCCGGGCACAAGATTGTCTCA-GCAGTGTCTCAGCATACGCA805'-AGTGTGCTCTTCTCAGGTCT-40N-GCAGTGTCTCAGCATACGCA-3'ssDNAHelicobacter PyloriH. pylori surface recombinant antigens (HP-Ag)Identify aptamers against H pylori surface recombinant antigens.N/AN/AFluorescence Binding AssayN/ADetectionSELEX5'-FAM LabeledN/AN/AN/AN/AN/A
ABdb_1244 309501492019Recognition of Helicobacter pylori by protein-targeting aptamersHp7AGTGTGCTCTTCTCAGGTCT-ACACAACCTGCCGTATTGTAACCGTCGTCCCCCCGAAGCA-GCAGTGTCTCAGCATACGCA805'-AGTGTGCTCTTCTCAGGTCT-40N-GCAGTGTCTCAGCATACGCA-3'ssDNAHelicobacter PyloriH. pylori surface recombinant antigens (HP-Ag)Identify aptamers against H pylori surface recombinant antigens.N/AN/AFluorescence Binding AssayN/ADetectionSELEX5'-FAM LabeledN/AN/AN/AN/AN/A
ABdb_1525 335857562021Rapid Detection of Helicobacter pylori by the Naked Eye Using DNA AptamersHPA-2AAGGAGCAGCGTGGAGGTTA-CCAGGAGGACCCTATTCTCGTGTATCGACGAGATCCAGTG-ACCACGACGACACACCCTAA805'-AAGGAGCAGCGTGGAGGTTA-N40-ACCACGACGACACACCCTAA-3'ssDNAHelicobacter Pylori (ATCC 43504)Whole cellIdentify aptamers that can detect H. pylori with no specificity for other bacteria.Limit of detection (LOD) of HPA-2 was 88 cfu/mL.9Fluorescence Spectroscopy19.3 ± 3.2 nMBiosensorSELEX5'-FAM LabeledN/AN/ABest CandidateN/AN/A
ABdb_1526 335857562021Rapid Detection of Helicobacter pylori by the Naked Eye Using DNA AptamersHPA-1AAGGAGCAGCGTGGAGGTTA-CGCCTGATCCAGGTGCTATCTTCCGCCCTGTTTCTTTGGT-ACCACGACGACACACCCTAA805'-AAGGAGCAGCGTGGAGGTTA-N40-ACCACGACGACACACCCTAA-3'ssDNAHelicobacter Pylori (ATCC 43504)Whole cellIdentify aptamers that can detect H. pylori with no specificity for other bacteria.N/A9Fluorescence SpectroscopyN/ABiosensorSELEX5'-FAM LabeledN/AN/AN/AN/AN/A
ABdb_1527 335857562021Rapid Detection of Helicobacter pylori by the Naked Eye Using DNA AptamersHPA-3AAGGAGCAGCGTGGAGGTTA-CTCCTCGGTCCTTTCAGGTAGACGCTCTTACGCCCTCAGT-ACCACGACGACACACCCTAA805'-AAGGAGCAGCGTGGAGGTTA-N40-ACCACGACGACACACCCTAA-3'ssDNAHelicobacter Pylori (ATCC 43504)Whole cellIdentify aptamers that can detect H. pylori with no specificity for other bacteria.The binding ability order was HPA-2 > HPA-3 > HPA-5 > HPA-9.9Fluorescence SpectroscopyN/ABiosensorSELEX5'-FAM LabeledN/AN/AN/AN/AN/A
ABdb_1528 335857562021Rapid Detection of Helicobacter pylori by the Naked Eye Using DNA AptamersHPA-4AAGGAGCAGCGTGGAGGTTA-CGTGTATCCCCTGTGTGTTTGTACTCGGCTACTGTATCCG-ACCACGACGACACACCCTAA805'-AAGGAGCAGCGTGGAGGTTA-N40-ACCACGACGACACACCCTAA-3'ssDNAHelicobacter Pylori (ATCC 43504)Whole cellIdentify aptamers that can detect H. pylori with no specificity for other bacteria.N/A9Fluorescence SpectroscopyN/ABiosensorSELEX5'-FAM LabeledN/AN/AN/AN/AN/A
ABdb_1529 335857562021Rapid Detection of Helicobacter pylori by the Naked Eye Using DNA AptamersHPA-5AAGGAGCAGCGTGGAGGTTA-CTCGTTTGGATACGTCATCGGTAGGACTACGGTACCTAAAC-ACCACGACGACACACCCTAA815'-AAGGAGCAGCGTGGAGGTTA-N40-ACCACGACGACACACCCTAA-3'ssDNAHelicobacter Pylori (ATCC 43504)Whole cellIdentify aptamers that can detect H. pylori with no specificity for other bacteria.The binding ability order was HPA-2 > HPA-3 > HPA-5 > HPA-9.9Fluorescence SpectroscopyN/ABiosensorSELEX5'-FAM LabeledN/AN/AN/AN/AN/A
ABdb_1530 335857562021Rapid Detection of Helicobacter pylori by the Naked Eye Using DNA AptamersHPA-6AAGGAGCAGCGTGGAGGTTA-GCACAGGAGACAGGGGGAGATGATACTCGGCGTTTCAAGG-ACCACGACGACACACCCTAA805'-AAGGAGCAGCGTGGAGGTTA-N40-ACCACGACGACACACCCTAA-3'ssDNAHelicobacter Pylori (ATCC 43504)Whole cellIdentify aptamers that can detect H. pylori with no specificity for other bacteria.N/A9Fluorescence SpectroscopyN/ABiosensorSELEX5'-FAM LabeledN/AN/AN/AN/AN/A
ABdb_1531 335857562021Rapid Detection of Helicobacter pylori by the Naked Eye Using DNA AptamersHPA-7AAGGAGCAGCGTGGAGGTTA-CTCGCGCCCTTCTTTCAGTAGCAGTGTACGGATCTTGCGG-ACCACGACGACACACCCTAA805'-AAGGAGCAGCGTGGAGGTTA-N40-ACCACGACGACACACCCTAA-3'ssDNAHelicobacter Pylori (ATCC 43504)Whole cellIdentify aptamers that can detect H. pylori with no specificity for other bacteria.N/A9Fluorescence SpectroscopyN/ABiosensorSELEX5'-FAM LabeledN/AN/AN/AN/AN/A
ABdb_1532 335857562021Rapid Detection of Helicobacter pylori by the Naked Eye Using DNA AptamersHPA-8AAGGAGCAGCGTGGAGGTTA-TGCATATCGCTAGCTGATAAGCTGATGCCATCGTGTCTAC-ACCACGACGACACACCCTAA805'-AAGGAGCAGCGTGGAGGTTA-N40-ACCACGACGACACACCCTAA-3'ssDNAHelicobacter Pylori (ATCC 43504)Whole cellIdentify aptamers that can detect H. pylori with no specificity for other bacteria.N/A9Fluorescence SpectroscopyN/ABiosensorSELEX5'-FAM LabeledN/AN/AN/AN/AN/A
ABdb_1533 335857562021Rapid Detection of Helicobacter pylori by the Naked Eye Using DNA AptamersHPA-9AAGGAGCAGCGTGGAGGTTA-GCATCTTTGAGGAATTTTCGTCAAAGGACCGAGTAACGGC-ACCACGACGACACACCCTAA805'-AAGGAGCAGCGTGGAGGTTA-N40-ACCACGACGACACACCCTAA-3'ssDNAHelicobacter Pylori (ATCC 43504)Whole cellIdentify aptamers that can detect H. pylori with no specificity for other bacteria.The binding ability order was HPA-2 > HPA-3 > HPA-5 > HPA-9.9Fluorescence SpectroscopyN/ABiosensorSELEX5'-FAM LabeledN/AN/AN/AN/AN/A
ABdb_1534 335857562021Rapid Detection of Helicobacter pylori by the Naked Eye Using DNA AptamersHPA-10AAGGAGCAGCGTGGAGGTTA-AGTTGCTCTTGATCGTCGACCAGTCGCTATGCAGCACCCC-ACCACGACGACACACCCTAA805'-AAGGAGCAGCGTGGAGGTTA-N40-ACCACGACGACACACCCTAA-3'ssDNAHelicobacter Pylori (ATCC 43504)Whole cellIdentify aptamers that can detect H. pylori with no specificity for other bacteria.N/A9Fluorescence SpectroscopyN/ABiosensorSELEX5'-FAM LabeledN/AN/AN/AN/AN/A
ABdb_1535 335857562021Rapid Detection of Helicobacter pylori by the Naked Eye Using DNA AptamersHPA-11AAGGAGCAGCGTGGAGGTTA-CTGCACGAATGATCCCCCGCCATGCTGTAGTTCCGTCTTA-ACCACGACGACACACCCTAA805'-AAGGAGCAGCGTGGAGGTTA-N40-ACCACGACGACACACCCTAA-3'ssDNAHelicobacter Pylori (ATCC 43504)Whole cellIdentify aptamers that can detect H. pylori with no specificity for other bacteria.N/A9Fluorescence SpectroscopyN/ABiosensorSELEX5'-FAM LabeledN/AN/AN/AN/AN/A
ABdb_1536 335857562021Rapid Detection of Helicobacter pylori by the Naked Eye Using DNA AptamersHPA-12AAGGAGCAGCGTGGAGGTTA-CTGTAACGCCCCGCTGATTCTTTCTCAGCGTGCTAGGCGG-ACCACGACGACACACCCTAA805'-AAGGAGCAGCGTGGAGGTTA-N40-ACCACGACGACACACCCTAA-3'ssDNAHelicobacter Pylori (ATCC 43504)Whole cellIdentify aptamers that can detect H. pylori with no specificity for other bacteria.N/A9Fluorescence SpectroscopyN/ABiosensorSELEX5'-FAM LabeledN/AN/AN/AN/AN/A
ABdb_1537 335857562021Rapid Detection of Helicobacter pylori by the Naked Eye Using DNA AptamersHPA-13AAGGAGCAGCGTGGAGGTTA-ATCGCTCCGTCCAGTAAGAGTTGCCTACAATGCCCGCCGGC-ACCACGACGACACACCCTAA815'-AAGGAGCAGCGTGGAGGTTA-N40-ACCACGACGACACACCCTAA-3'ssDNAHelicobacter Pylori (ATCC 43504)Whole cellIdentify aptamers that can detect H. pylori with no specificity for other bacteria.N/A9Fluorescence SpectroscopyN/ABiosensorSELEX5'-FAM LabeledN/AN/AN/AN/AN/A
ABdb_1538 335857562021Rapid Detection of Helicobacter pylori by the Naked Eye Using DNA AptamersHPA-14AAGGAGCAGCGTGGAGGTTA-CAAATGAGCCTTAGAGCTGTGCAGAGTTCGAAGCTTGGTG-ACCACGACGACACACCCTAA805'-AAGGAGCAGCGTGGAGGTTA-N40-ACCACGACGACACACCCTAA-3'ssDNAHelicobacter Pylori (ATCC 43504)Whole cellIdentify aptamers that can detect H. pylori with no specificity for other bacteria.N/A9Fluorescence SpectroscopyN/ABiosensorSELEX5'-FAM LabeledN/AN/AN/AN/AN/A
ABdb_1539 335857562021Rapid Detection of Helicobacter pylori by the Naked Eye Using DNA AptamersHPA-15AAGGAGCAGCGTGGAGGTTA-CCTCGGTGTTCGTTCTGACTACGTTCCCTGGGACCCGCGT-ACCACGACGACACACCCTAA805'-AAGGAGCAGCGTGGAGGTTA-N40-ACCACGACGACACACCCTAA-3'ssDNAHelicobacter Pylori (ATCC 43504)Whole cellIdentify aptamers that can detect H. pylori with no specificity for other bacteria.N/A9Fluorescence SpectroscopyN/ABiosensorSELEX5'-FAM LabeledN/AN/AN/AN/AN/A
ABdb_2124 343991932021Aptamer-superparamagnetic nanoparticles capture coupling siderophore-Fe3+ scavenging actuated with carbon dots to confer an "off-on" mechanism for the ultrasensitive detection of Helicobacter pyloriHp-1N/AN/A5'-TGGACCTTGCGATTGCGATTGACAGC-40N-GCAGACATGAGTCTCAGGAC-3'ssDNAHelicobacter Pylori (ATCC 700392)Whole cellAptamer-modified superparamagnetic nanoparticles (SPMNPs) are used to develop a triple-module biosensor to capture H. pylori.Exhibited a wide detection range of 10-10(7) CFU/mL and a limit of detection (LOD) as low as 1 CFU/mL.10Fluorescence Spectroscopy36.91 ± 11.1 nMBiosensorSELEX5'-FAM Labeled and 5'-Amidation (NH₂)N/AN/ABest CandidateN/AN/A
ABdb_2125 343991932021Aptamer-superparamagnetic nanoparticles capture coupling siderophore-Fe3+ scavenging actuated with carbon dots to confer an "off-on" mechanism for the ultrasensitive detection of Helicobacter pyloriHp-2N/AN/A5'-TGGACCTTGCGATTGCGATTGACAGC-40N-GCAGACATGAGTCTCAGGAC-3'ssDNAHelicobacter Pylori (ATCC 700392)Whole cellAptamer-modified superparamagnetic nanoparticles (SPMNPs) capture H. pylori.N/A10Fluorescence Spectroscopy46.31 ± 11.31 nMBiosensorSELEX5'-FAM Labeled and 5'-Amidation (NH₂)N/AN/AN/AN/AN/A
ABdb_2126 343991932021Aptamer-superparamagnetic nanoparticles capture coupling siderophore-Fe3+ scavenging actuated with carbon dots to confer an "off-on" mechanism for the ultrasensitive detection of Helicobacter pyloriHp-3N/AN/A5'-TGGACCTTGCGATTGCGATTGACAGC-40N-GCAGACATGAGTCTCAGGAC-3'ssDNAHelicobacter Pylori (ATCC 700392)Whole cellAptamer-modified superparamagnetic nanoparticles (SPMNPs) capture H. pylori.N/A10Fluorescence Spectroscopy60.76 ± 11.69 nMBiosensorSELEX5'-FAM Labeled and 5'-Amidation (NH₂)N/AN/AN/AN/AN/A
ABdb_2127 343991932021Aptamer-superparamagnetic nanoparticles capture coupling siderophore-Fe3+ scavenging actuated with carbon dots to confer an "off-on" mechanism for the ultrasensitive detection of Helicobacter pyloriHp-4N/AN/A5'-TGGACCTTGCGATTGCGATTGACAGC-40N-GCAGACATGAGTCTCAGGAC-3'ssDNAHelicobacter Pylori (ATCC 700392)Whole cellAptamer-modified superparamagnetic nanoparticles (SPMNPs) capture H. pylori.N/A10Fluorescence Spectroscopy41.57 ± 16.18 nMBiosensorSELEX5'-FAM Labeled and 5'-Amidation (NH₂)N/AN/AN/AN/AN/A
ABdb_2128 343991932021Aptamer-superparamagnetic nanoparticles capture coupling siderophore-Fe3+ scavenging actuated with carbon dots to confer an "off-on" mechanism for the ultrasensitive detection of Helicobacter pyloriHp-5N/AN/A5'-TGGACCTTGCGATTGCGATTGACAGC-40N-GCAGACATGAGTCTCAGGAC-3'ssDNAHelicobacter Pylori (ATCC 700392)Whole cellAptamer-modified superparamagnetic nanoparticles (SPMNPs) capture H. pylori.N/A10Fluorescence Spectroscopy67.74 ± 10.24 nMBiosensorSELEX5'-FAM Labeled and 5'-Amidation (NH₂)N/AN/AN/AN/AN/A