Target Organism : Haemophilus Influenzae

Total records found: 2

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AptBacDB_ID ⇅	PMID/DOI ⇅	Year ⇅	Title ⇅	Aptamer name ⇅	Sequence (5′ to 3′) ⇅	Length ⇅	Library ⇅	Type ⇅	Target Organism ⇅	Target ⇅	Objective/Mechanism ⇅	Outcome/Inhibitory effect ⇅	No. of selection round SELEX ⇅	Determination of affinity method ⇅	Kd value ⇅	Activity Role ⇅	Method ⇅	Modification ⇅	Cytotoxicity (cell viability) ⇅	Stability⇅	Potential Candidate ⇅	Half-life ⇅	Patent ⇅
ABdb_0814	26768582	2016	DNA aptamers for the detection of Haemophilus influenzae type b by cell SELEX	Clone 63	GCCTGTTGTGAGCCTCCTAAC-AGGAGGCGAACGGGCAGGTTCTTGGGGAGACAAGAATAAG-CATGCTTATTCTTGTCTCC	80	5'-GCCTGTTGTGAGCCTCCTAAC-N38-CATGCTTATTCTTGTCTCC-3'	ssDNA	Haemophilus Influenzae type b (Hib) (ATCC 10211)	Whole cell	Identify an aptamer against Hib for the detection of H. influenzae.	Clone 63 could detect Hib in patients’ CSF samples at 60 CFU/mL.	7	Flow Cytometry	28.46 pM	Detection	Whole Cell-SELEX	5'-FITC Labeled	N/A	N/A	Best Candidate	N/A	N/A
ABdb_0815	26768582	2016	DNA aptamers for the detection of Haemophilus influenzae type b by cell SELEX	Clone 2, 42, 45	GCCTGTTGTGAGCCTCCTAAC-GCCAGGTGTTTTGGCGGTAGGGGTGAAACAACAGGGGG-CATGCTTATTCTTGTCTCC	78	5'-GCCTGTTGTGAGCCTCCTAAC-N38-CATGCTTATTCTTGTCTCC-3'	ssDNA	Haemophilus Influenzae type b (Hib) (ATCC 10211)	Whole cell	Identify an aptamer against Hib for the detection of H. influenzae.	N/A	7	Flow Cytometry	47.10 pM	Detection	Whole Cell-SELEX	5'-FITC Labeled	N/A	N/A	N/A	N/A	N/A