Target Organism : Borrelia Burgdorferi

Total records found: 6

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AptBacDB_ID ⇅	PMID/DOI ⇅	Year ⇅	Title ⇅	Aptamer name ⇅	Sequence (5′ to 3′) ⇅	Length ⇅	Library ⇅	Type ⇅	Target Organism ⇅	Target ⇅	Objective/Mechanism ⇅	Outcome/Inhibitory effect ⇅	No. of selection round SELEX ⇅	Determination of affinity method ⇅	Kd value ⇅	Activity Role ⇅	Method ⇅	Modification ⇅	Cytotoxicity (cell viability) ⇅	Stability⇅	Potential Candidate ⇅	Half-life ⇅	Patent ⇅
ABdb_1642	35104673	2022	An antigen-targeting assay for Lyme disease: Combining aptamers and SERS to detect the OspA protein	Ion-OspA-59	CATGACACCGTACCTGCTCT-TGCTTTTCGTGCGCGCATAAAATACCTTGATACTGTGCCGTATGAAAGCG-AAGCACGCCAGGGACTATTA	90	5'-CATGACACCGTACCTGCTCT-N50-AAGCACGCCAGGGACTATTA-3'	ssDNA	Borrelia Burgdorferi	Outer Surface Protein A (OspA)	Develop SERS-based aptasensor to detect OspA in serum samples.	OspA limit-of-detection determined to be 1 × 10−4 ng/mL with 91% sensitivity and 96% specificity.	10	Fluorescence anisotropy (FA)	2.18 nM	Biosensor	RAPID-SELEX	5'-DTPA dithiol and T at 86 position is replaced by 5-Octadiynyl dU moeity	N/A	N/A	Best Candidate	N/A	N/A
ABdb_1643	35104673	2022	An antigen-targeting assay for Lyme disease: Combining aptamers and SERS to detect the OspA protein	Ion-OspA-21	CATGACACCGTACCTGCTCT-AATAAGCACGCCAGGGACTATTAGATCGGAATAGCACACGTCTGAACTCC-AAGCACGCCAGGGACTATTA	90	5'-CATGACACCGTACCTGCTCT-N50-AAGCACGCCAGGGACTATTA-3'	ssDNA	Borrelia Burgdorferi	Outer Surface Protein A (OspA)	Develop SERS-based aptasensor to detect OspA in serum samples.	N/A	10	Fluorescence anisotropy (FA)	N/A	Biosensor	RAPID-SELEX	5'-DTPA dithiol and T at 86 position is replaced by 5-Octadiynyl dU moeity	N/A	N/A	N/A	N/A	N/A
ABdb_1644	35104673	2022	An antigen-targeting assay for Lyme disease: Combining aptamers and SERS to detect the OspA protein	Ion-OspA-46	CATGACACCGTACCTGCTCT-AATAAGCACGCCAGGGACTATTAGATCGGAAGAGCACACGTGTGAACTCC-AAGCACGCCAGGGACTATTA	90	5'-CATGACACCGTACCTGCTCT-N50-AAGCACGCCAGGGACTATTA-3'	ssDNA	Borrelia Burgdorferi	Outer Surface Protein A (OspA)	Develop SERS-based aptasensor to detect OspA in serum samples.	N/A	10	Fluorescence anisotropy (FA)	N/A	Biosensor	RAPID-SELEX	5'-DTPA dithiol and T at 86 position is replaced by 5-Octadiynyl dU moeity	N/A	N/A	N/A	N/A	N/A
ABdb_1645	35104673	2022	An antigen-targeting assay for Lyme disease: Combining aptamers and SERS to detect the OspA protein	Ion-OspA-22	CATGACACCGTACCTGCTCT-ACGAGATTCAAGCACTCCAGGGACTATTAGATCGGAAGAGCACACGTCTG-AAGCACGCCAGGGACTATTA	90	5'-CATGACACCGTACCTGCTCT-N50-AAGCACGCCAGGGACTATTA-3'	ssDNA	Borrelia Burgdorferi	Outer Surface Protein A (OspA)	Develop SERS-based aptasensor to detect OspA in serum samples.	N/A	10	Fluorescence anisotropy (FA)	N/A	Biosensor	RAPID-SELEX	5'-DTPA dithiol and T at 86 position is replaced by 5-Octadiynyl dU moeity	N/A	N/A	N/A	N/A	N/A
ABdb_1646	35104673	2022	An antigen-targeting assay for Lyme disease: Combining aptamers and SERS to detect the OspA protein	Ion-OspA-39	CATGACACCGTACCTGCTCT-ACGAGATTCAAGCACGCCAGGGATTATTAGATCGGAAGAGCACACGTCTG-AAGCACGCCAGGGACTATTA	90	5'-CATGACACCGTACCTGCTCT-N50-AAGCACGCCAGGGACTATTA-3'	ssDNA	Borrelia Burgdorferi	Outer Surface Protein A (OspA)	Develop SERS-based aptasensor to detect OspA in serum samples.	N/A	10	Fluorescence anisotropy (FA)	N/A	Biosensor	RAPID-SELEX	5'-DTPA dithiol and T at 86 position is replaced by 5-Octadiynyl dU moeity	N/A	N/A	N/A	N/A	N/A
ABdb_1647	35104673	2022	An antigen-targeting assay for Lyme disease: Combining aptamers and SERS to detect the OspA protein	Ion-OspA-55	CATGACACCGTACCTGCTCT-TGCTTTTCGTGCGCGCATAAAATACTTTGATACTGTGCCGGATGAAAGCG-AAGCACGCCAGGGACTATTA	90	5'-CATGACACCGTACCTGCTCT-N50-AAGCACGCCAGGGACTATTA-3'	ssDNA	Borrelia Burgdorferi	Outer Surface Protein A (OspA)	Develop SERS-based aptasensor to detect OspA in serum samples.	N/A	10	Fluorescence anisotropy (FA)	N/A	Biosensor	RAPID-SELEX	5'-DTPA dithiol and T at 86 position is replaced by 5-Octadiynyl dU moeity	N/A	N/A	N/A	N/A	N/A