Target : Surface-specific Protein PavA

Total records found: 2

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AptBacDB_ID ⇅	PMID/DOI ⇅	Year ⇅	Title ⇅	Aptamer name ⇅	Sequence (5′ to 3′) ⇅	Length ⇅	Library ⇅	Type ⇅	Target Organism ⇅	Target ⇅	Objective/Mechanism ⇅	Outcome/Inhibitory effect ⇅	No. of selection round SELEX ⇅	Determination of affinity method ⇅	Kd value ⇅	Activity Role ⇅	Method ⇅	Modification ⇅	Cytotoxicity (cell viability) ⇅	Stability⇅	Potential Candidate ⇅	Half-life ⇅	Patent ⇅
ABdb_2113	https://doi.org/10.1016/j.snb.2017.02.098	2017	Selection of aptamers to Neisseria meningitidis and Streptococcus pneumoniae surface specific proteins and affinity assay using thin film AlN resonators	PA05	N/A	N/A	N/A	ssDNA	Streptococcus Pneumoniae	Surface-specific Protein PavA	Generated SOMAmers against surface-specific proteins PavA and FHbp and developed a gravimetric aptasensor for the detection of S. pneumoniae and N. meningitidis.	N/A	8	Enzyme-Linked Oligonucleotide Assay (ELONA)	N/A	Detection	SELEX	5'-DIG (Digoxigenin) Labeled and 5-tryptaminocarbonyl-dU (TrpdU))	N/A	N/A	N/A	N/A	N/A
ABdb_2114	https://doi.org/10.1016/j.snb.2017.02.098	2017	Selection of aptamers to Neisseria meningitidis and Streptococcus pneumoniae surface specific proteins and affinity assay using thin film AlN resonators	PA08	N/A	N/A	N/A	ssDNA	Streptococcus Pneumoniae	Surface-specific Protein PavA	Generated SOMAmers against surface-specific proteins PavA and FHbp and developed a gravimetric aptasensor for the detection of S. pneumoniae and N. meningitidis.	The polyclonal population PA08 showed a frequency shift four times greater and a faster reaction rate than FH05 when measured on the gravimetric sensor.	8	Enzyme-Linked Oligonucleotide Assay (ELONA)	N/A	Detection	SELEX	5'-DIG (Digoxigenin) Labeled and 5-tryptaminocarbonyl-dU (TrpdU))	N/A	N/A	Best Candidate	N/A	N/A