Target : Protective antigen (PA) of anthrax toxin

Total records found: 2

Download:

Search:

AptBacDB_ID ⇅	PMID/DOI ⇅	Year ⇅	Title ⇅	Aptamer name ⇅	Sequence (5′ to 3′) ⇅	Length ⇅	Library ⇅	Type ⇅	Target Organism ⇅	Target ⇅	Objective/Mechanism ⇅	Outcome/Inhibitory effect ⇅	No. of selection round SELEX ⇅	Determination of affinity method ⇅	Kd value ⇅	Activity Role ⇅	Method ⇅	Modification ⇅	Cytotoxicity (cell viability) ⇅	Stability⇅	Potential Candidate ⇅	Half-life ⇅	Patent ⇅
ABdb_0103	21743920	2011	Sensitive fluorescence assay of anthrax protective antigen with two new DNA aptamers and their binding properties	1–PA	GCGCGGATCCCGCGC-GATGTGGGTGTAGTTGGAGGGTAAACGTT-CGCGCGAAGCTTGCG	59	5'-GCGCGGATCCCGCGC-N30-CGCGCGAAGCTTGCG-3'	ssDNA	Bacillus Anthracis (BA)	Protective antigen (PA) of anthrax toxin	Detection of PA based on the reduction in the fluorescence emission according to the formation of the aptamer-PA ternary complex.	The limit of PA detection using this system was determined to be approximately 1 nM.	8	Fluorescence Microplate Reader (Fluorescence Spectroscopy)	8.53 nM	Biosensor	SELEX	N/A	N/A	N/A	N/A	N/A	Korea Pat., KR101152354B1 (2012-06-13)
ABdb_0104	21743920	2011	Sensitive fluorescence assay of anthrax protective antigen with two new DNA aptamers and their binding properties	2–PA	GCGCGGATCCCGCGC-CAGACCGTAAGGGATGCCGCCTAAACACC-CGCGCGAAGCTTGCG	59	5'-GCGCGGATCCCGCGC-N30-CGCGCGAAGCTTGCG-3'	ssDNA	Bacillus Anthracis (BA)	Protective antigen (PA) of anthrax toxin	Detection of PA based on the reduction in the fluorescence emission according to the formation of the aptamer-PA ternary complex.	The limit of PA detection using this system was determined to be approximately 1 nM.	8	Fluorescence Microplate Reader (Fluorescence Spectroscopy)	1.51 nM	Biosensor	SELEX	N/A	N/A	N/A	N/A	N/A	Korea Pat., KR101152354B1 (2012-06-13)