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| AptBacDB_ID ⇅ | PMID/DOI ⇅ | Year ⇅ | Title ⇅ | Aptamer name ⇅ | Sequence (5′ to 3′) ⇅ | Length ⇅ | Library ⇅ | Type ⇅ | Target Organism ⇅ | Target ⇅ | Objective/Mechanism ⇅ | Outcome/Inhibitory effect ⇅ | No. of selection round SELEX ⇅ | Determination of affinity method ⇅ | Kd value ⇅ | Activity Role ⇅ | Method ⇅ | Modification ⇅ | Cytotoxicity (cell viability) ⇅ | Stability⇅ | Potential Candidate ⇅ | Half-life ⇅ | Patent ⇅ |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ABdb_2088 | 28794178 | 2017 | Potential of High-Affinity, Slow Off-Rate Modified Aptamer Reagents for Mycobacterium tuberculosis Proteins as Tools for Infection Models and Diagnostic Applications | 5560-59 | N/A | N/A | N/A | ssDNA | Mycobacterium Tuberculosis (H37Rv) (NR-14865; BEI Resources) | MPT51 protein (Rv3803c) | Slow-off-rate modified aptamer (SOMAmer) for detecting TB. | N/A | N/A | Radiolabel Equilibration Binding Assay | 13.9 nM | Biosensor | N/A | 2NapdU and 5′PBDC (photocleavable biotin, D spacer, Cyanine3 (Cy3) Labeled) and 3’-Inverted Thymidine (3'-idT) | N/A | N/A | N/A | N/A | N/A |
| ABdb_2089 | 28794178 | 2017 | Potential of High-Affinity, Slow Off-Rate Modified Aptamer Reagents for Mycobacterium tuberculosis Proteins as Tools for Infection Models and Diagnostic Applications | 7619-25 | N/A | N/A | N/A | ssDNA | Mycobacterium Tuberculosis (H37Rv) (NR-14865; BEI Resources) | MPT51 protein (Rv3803c) | Slow-off-rate modified aptamer (SOMAmer) for detecting TB. | N/A | N/A | Radiolabel Equilibration Binding Assay | 11.1 nM | Biosensor | N/A | 2NapdU and 5′PBDC (photocleavable biotin, D spacer, Cyanine3 (Cy3) Labeled) and 3’-Inverted Thymidine (3'-idT) | N/A | N/A | N/A | N/A | N/A |
| ABdb_2090 | 28794178 | 2017 | Potential of High-Affinity, Slow Off-Rate Modified Aptamer Reagents for Mycobacterium tuberculosis Proteins as Tools for Infection Models and Diagnostic Applications | 14503-5 | N/A | N/A | N/A | ssDNA | Mycobacterium Tuberculosis (H37Rv) (NR-14865; BEI Resources) | MPT51 protein (Rv3803c) | Slow-off-rate modified aptamer (SOMAmer) for detecting TB. | N/A | N/A | Radiolabel Equilibration Binding Assay | 21.1 nM | Biosensor | N/A | PPdU and 5′PBDC (photocleavable biotin, D spacer, Cyanine3 (Cy3) Labeled) and 3’-Inverted Thymidine (3'-idT) | N/A | N/A | N/A | N/A | N/A |