Target : H. pylori surface recombinant antigens

Total records found: 7

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AptBacDB_ID ⇅	PMID/DOI ⇅	Year ⇅	Title ⇅	Aptamer name ⇅	Sequence (5′ to 3′) ⇅	Length ⇅	Library ⇅	Type ⇅	Target Organism ⇅	Target ⇅	Objective/Mechanism ⇅	Outcome/Inhibitory effect ⇅	No. of selection round SELEX ⇅	Determination of affinity method ⇅	Kd value ⇅	Activity Role ⇅	Method ⇅	Modification ⇅	Cytotoxicity (cell viability) ⇅	Stability⇅	Potential Candidate ⇅	Half-life ⇅	Patent ⇅
ABdb_1238	30950149	2019	Recognition of Helicobacter pylori by protein-targeting aptamers	Hp1	AGTGTGCTCTTCTCAGGTCT-GTGGCCGGGGGCACTAATGCGGGCTATAAGTCTCCTTGGG-GCAGTGTCTCAGCATACGCA	80	5'-AGTGTGCTCTTCTCAGGTCT-40N-GCAGTGTCTCAGCATACGCA-3'	ssDNA	Helicobacter Pylori	H. pylori surface recombinant antigens (HP-Ag)	Identify aptamers against H pylori surface recombinant antigens.	N/A	N/A	Fluorescence Binding Assay	35.60 ± 6.36 nM	Detection	SELEX	5'-FAM Labeled	N/A	N/A	N/A	N/A	N/A
ABdb_1239	30950149	2019	Recognition of Helicobacter pylori by protein-targeting aptamers	Hp2	AGTGTGCTCTTCTCAGGTCT-CCTATACCTGGCATCAGAGAGCTAGGGGCCACGGTTCGCA-GCAGTGTCTCAGCATACGCA	80	5'-AGTGTGCTCTTCTCAGGTCT-40N-GCAGTGTCTCAGCATACGCA-3'	ssDNA	Helicobacter Pylori	H. pylori surface recombinant antigens (HP-Ag)	Identify aptamers against H pylori surface recombinant antigens.	N/A	N/A	Fluorescence Binding Assay	204.38 ± 97.31 nM	Detection	SELEX	5'-FAM Labeled	N/A	N/A	N/A	N/A	N/A
ABdb_1240	30950149	2019	Recognition of Helicobacter pylori by protein-targeting aptamers	Hp3	AGTGTGCTCTTCTCAGGTCT-GGTGCTGCGATGCTTTCTGGTGGTGTATGGTTGTCTTTTG-GCAGTGTCTCAGCATACGCA	80	5'-AGTGTGCTCTTCTCAGGTCT-40N-GCAGTGTCTCAGCATACGCA-3'	ssDNA	Helicobacter Pylori	H. pylori surface recombinant antigens (HP-Ag)	Identify aptamers against H pylori surface recombinant antigens.	N/A	N/A	Fluorescence Binding Assay	N/A	Detection	SELEX	5'-FAM Labeled	N/A	N/A	N/A	N/A	N/A
ABdb_1241	30950149	2019	Recognition of Helicobacter pylori by protein-targeting aptamers	Hp4	AGTGTGCTCTTCTCAGGTCT-CGGCGCGGTTGTGGGTACCTAGGGTTGTTGTTGCTTCTCA-GCAGTGTCTCAGCATACGCA	80	5'-AGTGTGCTCTTCTCAGGTCT-40N-GCAGTGTCTCAGCATACGCA-3'	ssDNA	Helicobacter Pylori	H. pylori surface recombinant antigens (HP-Ag)	Identify aptamers against H pylori surface recombinant antigens.	Hp4 had excellent binding to H pylori cells and almost no binding to E coli, S aureus, or V anguillarum.	N/A	Fluorescence Binding Assay	26.48 ± 5.72 nM	Detection	SELEX	5'-FAM Labeled	N/A	N/A	Best Candidate	N/A	N/A
ABdb_1242	30950149	2019	Recognition of Helicobacter pylori by protein-targeting aptamers	Hp5	AGTGTGCTCTTCTCAGGTCT-GGGCTGTGGGTCGGCACGTCGTCTCTTCATGGTTGTGGTG-GCAGTGTCTCAGCATACGCA	80	5'-AGTGTGCTCTTCTCAGGTCT-40N-GCAGTGTCTCAGCATACGCA-3'	ssDNA	Helicobacter Pylori	H. pylori surface recombinant antigens (HP-Ag)	Identify aptamers against H pylori surface recombinant antigens.	N/A	N/A	Fluorescence Binding Assay	N/A	Detection	SELEX	5'-FAM Labeled	N/A	N/A	N/A	N/A	N/A
ABdb_1243	30950149	2019	Recognition of Helicobacter pylori by protein-targeting aptamers	Hp6	AGTGTGCTCTTCTCAGGTCT-TTAGGGACCCATGGGCTAACCCGGGCACAAGATTGTCTCA-GCAGTGTCTCAGCATACGCA	80	5'-AGTGTGCTCTTCTCAGGTCT-40N-GCAGTGTCTCAGCATACGCA-3'	ssDNA	Helicobacter Pylori	H. pylori surface recombinant antigens (HP-Ag)	Identify aptamers against H pylori surface recombinant antigens.	N/A	N/A	Fluorescence Binding Assay	N/A	Detection	SELEX	5'-FAM Labeled	N/A	N/A	N/A	N/A	N/A
ABdb_1244	30950149	2019	Recognition of Helicobacter pylori by protein-targeting aptamers	Hp7	AGTGTGCTCTTCTCAGGTCT-ACACAACCTGCCGTATTGTAACCGTCGTCCCCCCGAAGCA-GCAGTGTCTCAGCATACGCA	80	5'-AGTGTGCTCTTCTCAGGTCT-40N-GCAGTGTCTCAGCATACGCA-3'	ssDNA	Helicobacter Pylori	H. pylori surface recombinant antigens (HP-Ag)	Identify aptamers against H pylori surface recombinant antigens.	N/A	N/A	Fluorescence Binding Assay	N/A	Detection	SELEX	5'-FAM Labeled	N/A	N/A	N/A	N/A	N/A