Target : Exotoxin A

Total records found: 16

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AptBacDB_ID ⇅	PMID/DOI ⇅	Year ⇅	Title ⇅	Aptamer name ⇅	Sequence (5′ to 3′) ⇅	Length ⇅	Library ⇅	Type ⇅	Target Organism ⇅	Target ⇅	Objective/Mechanism ⇅	Outcome/Inhibitory effect ⇅	No. of selection round SELEX ⇅	Determination of affinity method ⇅	Kd value ⇅	Activity Role ⇅	Method ⇅	Modification ⇅	Cytotoxicity (cell viability) ⇅	Stability⇅	Potential Candidate ⇅	Half-life ⇅	Patent ⇅
ABdb_0656	26636098	2015	Selection of Single-Stranded DNA Molecular Recognition Elements against Exotoxin A Using a Novel Decoy-SELEX Method and Sensitive Detection of Exotoxin A in Human Serum	R14.33	TGTACCGTCTGAGCGATTCGTAC-CATAGGGTGCTTTTCAAGGCCACACGTTAGTGTA-AGCCAGTCAGTGTTAAGGAGTGC	80	5'-TGTACCGTCTGAGCGATTCGTAC-34N-AGCCAGTCAGTGTTAAGGAGTGC-3'	ssDNA	Pseudomonas Aeruginosa	Exotoxin A	Identify ssDNA MREs against Exotoxin A and develop a sandwich ELISA for its detection in human serum.	100 nM or 6.6 μg/mL of Exotoxin A in human serum was detected.	14	Surface Plasmon Resonance (SPR)	4.2 and 4.5 μM	Diagnostic	Decoy-SELEX	5'-Amidation (NH₂-(CH2)6) and 5'-Biotinylated	N/A	N/A	Best Candidate	N/A	N/A
ABdb_0657	26636098	2015	Selection of Single-Stranded DNA Molecular Recognition Elements against Exotoxin A Using a Novel Decoy-SELEX Method and Sensitive Detection of Exotoxin A in Human Serum	R14.02	TGTACCGTCTGAGCGATTCGTAC-TACGCCACACGTGGTGAGGGATTCGATCGCTTGA-AGCCAGTCAGTGTTAAGGAGTGC	80	5'-TGTACCGTCTGAGCGATTCGTAC-34N-AGCCAGTCAGTGTTAAGGAGTGC-3'	ssDNA	Pseudomonas Aeruginosa	Exotoxin A	Identify ssDNA MREs against Exotoxin A and develop a sandwich ELISA for its detection in human serum.	N/A	14	N/A	N/A	Diagnostic	Decoy-SELEX	N/A	N/A	N/A	Best Candidate	N/A	N/A
ABdb_0658	26636098	2015	Selection of Single-Stranded DNA Molecular Recognition Elements against Exotoxin A Using a Novel Decoy-SELEX Method and Sensitive Detection of Exotoxin A in Human Serum	R14.20	TGTACCGTCTGAGCGATTCGTAC-TGCTATTCATCACCACTCTAGAGCCACTTTTAAA-AGCCAGTCAGTGTTAAGGAGTGC	80	5'-TGTACCGTCTGAGCGATTCGTAC-34N-AGCCAGTCAGTGTTAAGGAGTGC-3'	ssDNA	Pseudomonas Aeruginosa	Exotoxin A	Identify ssDNA MREs against Exotoxin A and develop a sandwich ELISA for its detection in human serum.	N/A	14	N/A	N/A	Diagnostic	Decoy-SELEX	N/A	N/A	N/A	N/A	N/A	N/A
ABdb_0659	26636098	2015	Selection of Single-Stranded DNA Molecular Recognition Elements against Exotoxin A Using a Novel Decoy-SELEX Method and Sensitive Detection of Exotoxin A in Human Serum	R14.22	TGTACCGTCTGAGCGATTCGTAC-TGGGCGGCGAGCCACCCGGCAATTTAGTACAGGC-AGCCAGTCAGTGTTAAGGAGTGC	80	5'-TGTACCGTCTGAGCGATTCGTAC-34N-AGCCAGTCAGTGTTAAGGAGTGC-3'	ssDNA	Pseudomonas Aeruginosa	Exotoxin A	Identify ssDNA MREs against Exotoxin A and develop a sandwich ELISA for its detection in human serum.	N/A	14	N/A	N/A	Diagnostic	Decoy-SELEX	N/A	N/A	N/A	N/A	N/A	N/A
ABdb_0660	26636098	2015	Selection of Single-Stranded DNA Molecular Recognition Elements against Exotoxin A Using a Novel Decoy-SELEX Method and Sensitive Detection of Exotoxin A in Human Serum	R14.36	TGTACCGTCTGAGCGATTCGTAC-AAAGCATCCAGCCGGTATGTGCCAGAGTCTCTGA-AGCCAGTCAGTGTTAAGGAGTGC	80	5'-TGTACCGTCTGAGCGATTCGTAC-34N-AGCCAGTCAGTGTTAAGGAGTGC-3'	ssDNA	Pseudomonas Aeruginosa	Exotoxin A	Identify ssDNA MREs against Exotoxin A and develop a sandwich ELISA for its detection in human serum.	N/A	14	N/A	N/A	Diagnostic	Decoy-SELEX	N/A	N/A	N/A	N/A	N/A	N/A
ABdb_0661	26636098	2015	Selection of Single-Stranded DNA Molecular Recognition Elements against Exotoxin A Using a Novel Decoy-SELEX Method and Sensitive Detection of Exotoxin A in Human Serum	R14.38	TGTACCGTCTGAGCGATTCGTAC-AAATGTGAGTGGCCAGGCATCAGGTACGTCGGTA-AGCCAGTCAGTGTTAAGGAGTGC	80	5'-TGTACCGTCTGAGCGATTCGTAC-34N-AGCCAGTCAGTGTTAAGGAGTGC-3'	ssDNA	Pseudomonas Aeruginosa	Exotoxin A	Identify ssDNA MREs against Exotoxin A and develop a sandwich ELISA for its detection in human serum.	N/A	14	N/A	N/A	Diagnostic	Decoy-SELEX	N/A	N/A	N/A	N/A	N/A	N/A
ABdb_0662	26636098	2015	Selection of Single-Stranded DNA Molecular Recognition Elements against Exotoxin A Using a Novel Decoy-SELEX Method and Sensitive Detection of Exotoxin A in Human Serum	R14.03	TGTACCGTCTGAGCGATTCGTAC-GGATAGGTGCCTCTGCTTCATCATGTTGAACTTA-AGCCAGTCAGTGTTAAGGAGTGC	80	5'-TGTACCGTCTGAGCGATTCGTAC-34N-AGCCAGTCAGTGTTAAGGAGTGC-3'	ssDNA	Pseudomonas Aeruginosa	Exotoxin A	Identify ssDNA MREs against Exotoxin A and develop a sandwich ELISA for its detection in human serum.	N/A	14	N/A	N/A	Diagnostic	Decoy-SELEX	N/A	N/A	N/A	N/A	N/A	N/A
ABdb_0663	26636098	2015	Selection of Single-Stranded DNA Molecular Recognition Elements against Exotoxin A Using a Novel Decoy-SELEX Method and Sensitive Detection of Exotoxin A in Human Serum	R14.13	TGTACCGTCTGAGCGATTCGTAC-AGTTTCACCAGTCGCCTGTTAGCCGTGATATACG-AGCCAGTCAGTGTTAAGGAGTGC	80	5'-TGTACCGTCTGAGCGATTCGTAC-34N-AGCCAGTCAGTGTTAAGGAGTGC-3'	ssDNA	Pseudomonas Aeruginosa	Exotoxin A	Identify ssDNA MREs against Exotoxin A and develop a sandwich ELISA for its detection in human serum.	N/A	14	N/A	N/A	Diagnostic	Decoy-SELEX	N/A	N/A	N/A	N/A	N/A	N/A
ABdb_0664	26636098	2015	Selection of Single-Stranded DNA Molecular Recognition Elements against Exotoxin A Using a Novel Decoy-SELEX Method and Sensitive Detection of Exotoxin A in Human Serum	R14.27	TGTACCGTCTGAGCGATTCGTAC-TGTCAATATTACGTTGCTCTTAGGTTCACCATCT-AGCCAGTCAGTGTTAAGGAGTGC	80	5'-TGTACCGTCTGAGCGATTCGTAC-34N-AGCCAGTCAGTGTTAAGGAGTGC-3'	ssDNA	Pseudomonas Aeruginosa	Exotoxin A	Identify ssDNA MREs against Exotoxin A and develop a sandwich ELISA for its detection in human serum.	N/A	14	N/A	N/A	Diagnostic	Decoy-SELEX	N/A	N/A	N/A	N/A	N/A	N/A
ABdb_0665	26636098	2015	Selection of Single-Stranded DNA Molecular Recognition Elements against Exotoxin A Using a Novel Decoy-SELEX Method and Sensitive Detection of Exotoxin A in Human Serum	R14.28	TGTACCGTCTGAGCGATTCGTAC-TTGTGATTCAAATAGGCGTGTTGGTGTGAGACCT-AGCCAGTCAGTGTTAAGGAGTGC	80	5'-TGTACCGTCTGAGCGATTCGTAC-34N-AGCCAGTCAGTGTTAAGGAGTGC-3'	ssDNA	Pseudomonas Aeruginosa	Exotoxin A	Identify ssDNA MREs against Exotoxin A and develop a sandwich ELISA for its detection in human serum.	N/A	14	N/A	N/A	Diagnostic	Decoy-SELEX	N/A	N/A	N/A	N/A	N/A	N/A
ABdb_0666	26636098	2015	Selection of Single-Stranded DNA Molecular Recognition Elements against Exotoxin A Using a Novel Decoy-SELEX Method and Sensitive Detection of Exotoxin A in Human Serum	R14.23	TGTACCGTCTGAGCGATTCGTAC-CGTGGATCATGCTTCGCGTCGGTTTATAGGTTCC-AGCCAGTCAGTGTTAAGGAGTGC	80	5'-TGTACCGTCTGAGCGATTCGTAC-34N-AGCCAGTCAGTGTTAAGGAGTGC-3'	ssDNA	Pseudomonas Aeruginosa	Exotoxin A	Identify ssDNA MREs against Exotoxin A and develop a sandwich ELISA for its detection in human serum.	N/A	14	N/A	N/A	Diagnostic	Decoy-SELEX	N/A	N/A	N/A	N/A	N/A	N/A
ABdb_0667	26636098	2015	Selection of Single-Stranded DNA Molecular Recognition Elements against Exotoxin A Using a Novel Decoy-SELEX Method and Sensitive Detection of Exotoxin A in Human Serum	R14.39	TGTACCGTCTGAGCGATTCGTAC-AGAAGAGCATCGGTAACTTCCATAGGAGATGGGG-AGCCAGTCAGTGTTAAGGAGTGC	80	5'-TGTACCGTCTGAGCGATTCGTAC-34N-AGCCAGTCAGTGTTAAGGAGTGC-3'	ssDNA	Pseudomonas Aeruginosa	Exotoxin A	Identify ssDNA MREs against Exotoxin A and develop a sandwich ELISA for its detection in human serum.	N/A	14	N/A	N/A	Diagnostic	Decoy-SELEX	N/A	N/A	N/A	N/A	N/A	N/A
ABdb_0668	26636098	2015	Selection of Single-Stranded DNA Molecular Recognition Elements against Exotoxin A Using a Novel Decoy-SELEX Method and Sensitive Detection of Exotoxin A in Human Serum	R14.06	TGTACCGTCTGAGCGATTCGTAC-CATCCGAGGGTATTGTATGCGTATATCCTAGTCG-AGCCAGTCAGTGTTAAGGAGTGC	80	5'-TGTACCGTCTGAGCGATTCGTAC-34N-AGCCAGTCAGTGTTAAGGAGTGC-3'	ssDNA	Pseudomonas Aeruginosa	Exotoxin A	Identify ssDNA MREs against Exotoxin A and develop a sandwich ELISA for its detection in human serum.	N/A	14	N/A	N/A	Diagnostic	Decoy-SELEX	N/A	N/A	N/A	N/A	N/A	N/A
ABdb_0669	26636098	2015	Selection of Single-Stranded DNA Molecular Recognition Elements against Exotoxin A Using a Novel Decoy-SELEX Method and Sensitive Detection of Exotoxin A in Human Serum	R14.10	TGTACCGTCTGAGCGATTCGTAC-CAAGTTCCTCATGGAGGGTGCTCAGAGCTTAGAC-AGCCAGTCAGTGTTAAGGAGTAA	80	5'-TGTACCGTCTGAGCGATTCGTAC-34N-AGCCAGTCAGTGTTAAGGAGTGC-3'	ssDNA	Pseudomonas Aeruginosa	Exotoxin A	Identify ssDNA MREs against Exotoxin A and develop a sandwich ELISA for its detection in human serum.	N/A	14	N/A	N/A	Diagnostic	Decoy-SELEX	N/A	N/A	N/A	N/A	N/A	N/A
ABdb_0670	26636098	2015	Selection of Single-Stranded DNA Molecular Recognition Elements against Exotoxin A Using a Novel Decoy-SELEX Method and Sensitive Detection of Exotoxin A in Human Serum	R14.34	TGTACCGTCTGAGCGATTCGTAC-AGGGGGATTCCTAGGGCCCGGCCCAACGCTGTTT-AGCCAGTCAGTGTTAAGGAGTGC	80	5'-TGTACCGTCTGAGCGATTCGTAC-34N-AGCCAGTCAGTGTTAAGGAGTGC-3'	ssDNA	Pseudomonas Aeruginosa	Exotoxin A	Identify ssDNA MREs against Exotoxin A and develop a sandwich ELISA for its detection in human serum.	N/A	14	N/A	N/A	Diagnostic	Decoy-SELEX	N/A	N/A	N/A	N/A	N/A	N/A
ABdb_0671	26636098	2015	Selection of Single-Stranded DNA Molecular Recognition Elements against Exotoxin A Using a Novel Decoy-SELEX Method and Sensitive Detection of Exotoxin A in Human Serum	R14.42	TGTACCGTCTGAGCGATTCGTAC-CAAGACCCTTGAATCACGGGTAGGGTCTCGTAAC-AGCCAGTCAGTGTTAAGGAGTGC	80	5'-TGTACCGTCTGAGCGATTCGTAC-34N-AGCCAGTCAGTGTTAAGGAGTGC-3'	ssDNA	Pseudomonas Aeruginosa	Exotoxin A	Identify ssDNA MREs against Exotoxin A and develop a sandwich ELISA for its detection in human serum.	N/A	14	N/A	N/A	Diagnostic	Decoy-SELEX	N/A	N/A	N/A	N/A	N/A	N/A