AptBacterialDB

Target : ESXA (Rv3875 gene)

Total records found: 2

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AptBacDB_ID ⇅ PMID/DOI ⇅ Year ⇅ Title ⇅ Aptamer name ⇅ Sequence (5′ to 3′) ⇅ Length ⇅ Library ⇅ Type ⇅ Target Organism ⇅ Target ⇅ Objective/Mechanism ⇅ Outcome/Inhibitory effect ⇅ No. of selection round SELEX ⇅ Determination of affinity method ⇅ Kd value ⇅ Activity Role ⇅ Method ⇅ Modification ⇅ Cytotoxicity (cell viability) ⇅ Stability⇅ Potential Candidate ⇅ Half-life ⇅ Patent ⇅
ABdb_2068 287941782017Potential of High-Affinity, Slow Off-Rate Modified Aptamer Reagents for Mycobacterium tuberculosis Proteins as Tools for Infection Models and Diagnostic Applications7612-56N/AN/AN/AssDNAMycobacterium Tuberculosis (H37Rv) (NR-14865; BEI Resources)ESXA (Rv3875 gene)Slow-off-rate modified aptamer (SOMAmer) for detecting TB.N/AN/ARadiolabel Equilibration Binding Assay41.4 nMBiosensorN/ATrpdU and 5′PBDC (photocleavable biotin, D spacer, Cyanine3 (Cy3) Labeled) and 3’-Inverted Thymidine (3'-idT)N/AN/AN/AN/AN/A
ABdb_2069 287941782017Potential of High-Affinity, Slow Off-Rate Modified Aptamer Reagents for Mycobacterium tuberculosis Proteins as Tools for Infection Models and Diagnostic Applications7620-5N/AN/AN/AssDNAMycobacterium Tuberculosis (H37Rv) (NR-14865; BEI Resources)ESXA (Rv3875 gene)Slow-off-rate modified aptamer (SOMAmer) for detecting TB.N/AN/ARadiolabel Equilibration Binding Assay54.7 nMBiosensorN/A2NapdU and 5′PBDC (photocleavable biotin, D spacer, Cyanine3 (Cy3) Labeled) and 3’-Inverted Thymidine (3'-idT)N/AN/AN/AN/AN/A