AptBacterialDB

Target : CH10 (Rv3418c gene)

Total records found: 6

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AptBacDB_ID ⇅ PMID/DOI ⇅ Year ⇅ Title ⇅ Aptamer name ⇅ Sequence (5′ to 3′) ⇅ Length ⇅ Library ⇅ Type ⇅ Target Organism ⇅ Target ⇅ Objective/Mechanism ⇅ Outcome/Inhibitory effect ⇅ No. of selection round SELEX ⇅ Determination of affinity method ⇅ Kd value ⇅ Activity Role ⇅ Method ⇅ Modification ⇅ Cytotoxicity (cell viability) ⇅ Stability⇅ Potential Candidate ⇅ Half-life ⇅ Patent ⇅
ABdb_2055 287941782017Potential of High-Affinity, Slow Off-Rate Modified Aptamer Reagents for Mycobacterium tuberculosis Proteins as Tools for Infection Models and Diagnostic Applications7595-51N/AN/AN/AssDNAMycobacterium Tuberculosis (H37Rv) (NR-14865; BEI Resources)CH10 (Rv3418c gene)Slow-off-rate modified aptamer (SOMAmer) for detecting TB.N/AN/ARadiolabel Equilibration Binding Assay0.43 nMBiosensorN/A2NapdU and 5′PBDC (photocleavable biotin, D spacer, Cyanine3 (Cy3) Labeled) and 3’-Inverted Thymidine (3'-idT)N/AN/AN/AN/AN/A
ABdb_2056 287941782017Potential of High-Affinity, Slow Off-Rate Modified Aptamer Reagents for Mycobacterium tuberculosis Proteins as Tools for Infection Models and Diagnostic Applications7600-67N/AN/AN/AssDNAMycobacterium Tuberculosis (H37Rv) (NR-14865; BEI Resources)CH10 (Rv3418c gene)Slow-off-rate modified aptamer (SOMAmer) for detecting TB.N/AN/ARadiolabel Equilibration Binding Assay9.45 nMBiosensorN/ABndU and 5′PBDC (photocleavable biotin, D spacer, Cyanine3 (Cy3) Labeled) and 3’-Inverted Thymidine (3'-idT)N/AN/AN/AN/AN/A
ABdb_2057 287941782017Potential of High-Affinity, Slow Off-Rate Modified Aptamer Reagents for Mycobacterium tuberculosis Proteins as Tools for Infection Models and Diagnostic Applications7608-61N/AN/AN/AssDNAMycobacterium Tuberculosis (H37Rv) (NR-14865; BEI Resources)CH10 (Rv3418c gene)Slow-off-rate modified aptamer (SOMAmer) for detecting TB.N/AN/ARadiolabel Equilibration Binding Assay11.1 nMBiosensorN/ATrpdU and 5′PBDC (photocleavable biotin, D spacer, Cyanine3 (Cy3) Labeled) and 3’-Inverted Thymidine (3'-idT)N/AN/AN/AN/AN/A
ABdb_2058 287941782017Potential of High-Affinity, Slow Off-Rate Modified Aptamer Reagents for Mycobacterium tuberculosis Proteins as Tools for Infection Models and Diagnostic Applications12067-1N/AN/AN/AssDNAMycobacterium Tuberculosis (H37Rv) (NR-14865; BEI Resources)CH10 (Rv3418c gene)Slow-off-rate modified aptamer (SOMAmer) for detecting TB.N/AN/ARadiolabel Equilibration Binding Assay7.55 nMBiosensorN/ANapdU and 5′PBDC (photocleavable biotin, D spacer, Cyanine3 (Cy3) Labeled) and 3’-Inverted Thymidine (3'-idT)N/AN/AN/AN/AN/A
ABdb_2059 287941782017Potential of High-Affinity, Slow Off-Rate Modified Aptamer Reagents for Mycobacterium tuberculosis Proteins as Tools for Infection Models and Diagnostic Applications14488-1N/AN/AN/AssDNAMycobacterium Tuberculosis (H37Rv) (NR-14865; BEI Resources)CH10 (Rv3418c gene)Slow-off-rate modified aptamer (SOMAmer) for detecting TB.Exhibit LOD of 0.40 pM, 0.84 pM, 1.94 pM and 1.1 × 10(6) cells/ml in Buffer, Normal serum(40%), Urine protein (100 μg) and serum bacterial load, respectively.N/ARadiolabel Equilibration Binding Assay0.53 nMBiosensorN/A2NapdU and 5′PBDC (photocleavable biotin, D spacer, Cyanine3 (Cy3) Labeled) and 3’-Inverted Thymidine (3'-idT)N/AN/ABest CandidateN/AN/A
ABdb_2060 287941782017Potential of High-Affinity, Slow Off-Rate Modified Aptamer Reagents for Mycobacterium tuberculosis Proteins as Tools for Infection Models and Diagnostic Applications14488-3N/AN/AN/AssDNAMycobacterium Tuberculosis (H37Rv) (NR-14865; BEI Resources)CH10 (Rv3418c gene)Slow-off-rate modified aptamer (SOMAmer) for detecting TB.N/AN/ARadiolabel Equilibration Binding Assay0.05 nMBiosensorN/A2NapdU and 5′PBDC (photocleavable biotin, D spacer, Cyanine3 (Cy3) Labeled) and 3’-Inverted Thymidine (3'-idT)N/AN/AN/AN/AN/A