AptBacterialDB

Target : CFP-10 and ESAT-6 monomer and heterodimer

Total records found: 5

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AptBacDB_ID ⇅ PMID/DOI ⇅ Year ⇅ Title ⇅ Aptamer name ⇅ Sequence (5′ to 3′) ⇅ Length ⇅ Library ⇅ Type ⇅ Target Organism ⇅ Target ⇅ Objective/Mechanism ⇅ Outcome/Inhibitory effect ⇅ No. of selection round SELEX ⇅ Determination of affinity method ⇅ Kd value ⇅ Activity Role ⇅ Method ⇅ Modification ⇅ Cytotoxicity (cell viability) ⇅ Stability⇅ Potential Candidate ⇅ Half-life ⇅ Patent ⇅
ABdb_1959 230564922012Selection and application of ssDNA aptamers to detect active TB from sputum samplesCSIR 2.11N/AN/A5'-GCCTGTTGTGAGCCTCCTAAC-N49-CATGCTTATTCTTGTCTCCC-3'ssDNAMycobacterium Tuberculosis (M.Tb.)CFP-10 and ESAT-6 monomer and heterodimerIdentify aptamers against the CFP-10.ESAT-6 heterodimer and active TB from human sputum samples.CSIR 2.11 achieved 100% sensitivity and 68.75% specificity in detecting antigen in sputum samples.6Surface Plasmon Resonance (SPR)8 ± 1.07 nMDetectionSELEXBiotinylatedN/AN/ABest CandidateN/AN/A
ABdb_1960 230564922012Selection and application of ssDNA aptamers to detect active TB from sputum samplesCSIR 2.19N/AN/A5'-GCCTGTTGTGAGCCTCCTAAC-N49-CATGCTTATTCTTGTCTCCC-3'ssDNAMycobacterium Tuberculosis (M.Tb.)CFP-10 and ESAT-6 monomer and heterodimerIdentify aptamers against the CFP-10.ESAT-6 heterodimer and active TB from human sputum samples.N/A6Surface Plasmon Resonance (SPR)1.6 ± 0.5 nMDetectionSELEXBiotinylatedN/AN/AN/AN/AN/A
ABdb_1961 230564922012Selection and application of ssDNA aptamers to detect active TB from sputum samplesCSIR 2.2N/AN/A5'-GCCTGTTGTGAGCCTCCTAAC-N49-CATGCTTATTCTTGTCTCCC-3'ssDNAMycobacterium Tuberculosis (M.Tb.)CFP-10 and ESAT-6 monomer and heterodimerIdentify aptamers against the CFP-10.ESAT-6 heterodimer and active TB from human sputum samples.N/A6Surface Plasmon Resonance (SPR)21.5 ± 4.3 nMDetectionSELEXBiotinylatedN/AN/AN/AN/AN/A
ABdb_1962 230564922012Selection and application of ssDNA aptamers to detect active TB from sputum samplesCSIR 2.15N/AN/A5'-GCCTGTTGTGAGCCTCCTAAC-N49-CATGCTTATTCTTGTCTCCC-3'ssDNAMycobacterium Tuberculosis (M.Tb.)CFP-10 and ESAT-6 monomer and heterodimerIdentify aptamers against the CFP-10.ESAT-6 heterodimer and active TB from human sputum samples.N/A6Surface Plasmon Resonance (SPR)12 ± 1.6 nMDetectionSELEXBiotinylatedN/AN/AN/AN/AN/A
ABdb_1963 230564922012Selection and application of ssDNA aptamers to detect active TB from sputum samplesCSIR 2.21N/AN/A5'-GCCTGTTGTGAGCCTCCTAAC-N49-CATGCTTATTCTTGTCTCCC-3'ssDNAMycobacterium Tuberculosis (M.Tb.)CFP-10 and ESAT-6 monomer and heterodimerIdentify aptamers against the CFP-10.ESAT-6 heterodimer and active TB from human sputum samples.N/A6Surface Plasmon Resonance (SPR)10.2 ± 3.4 nMDetectionSELEXBiotinylatedN/AN/AN/AN/AN/A