AptBacterialDB

Target : Antigen 85 (Ag85A) (FbpA)

Total records found: 2

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AptBacDB_ID ⇅ PMID/DOI ⇅ Year ⇅ Title ⇅ Aptamer name ⇅ Sequence (5′ to 3′) ⇅ Length ⇅ Library ⇅ Type ⇅ Target Organism ⇅ Target ⇅ Objective/Mechanism ⇅ Outcome/Inhibitory effect ⇅ No. of selection round SELEX ⇅ Determination of affinity method ⇅ Kd value ⇅ Activity Role ⇅ Method ⇅ Modification ⇅ Cytotoxicity (cell viability) ⇅ Stability⇅ Potential Candidate ⇅ Half-life ⇅ Patent ⇅
ABdb_0830 295945922017Selection of DNA aptamers against Mycobacterium tuberculosis Ag85A, and its application in a graphene oxide-based fluorometric assayApt22GCTGTGTGACTCCTGCAA-GCGGGAAGAGGGTAAGGGGAGGGAGGGTAACGCGGAGAAGGCAA-GCAGCTGTATCTTGTCTCC815'-GCTGTGTGACTCCTGCAA-N43-GCAGCTGTATCTTGTCTCC-3'ssDNAMycobacterium Tuberculosis (M.Tb.)Antigen 85 (Ag85A) (FbpA)Identify aptamers that bind to and develop a graphene oxide-based fluorometric assay to detect FbpA.Display LOD in PBS and serum of 1.5 nM and 2.1 nM, respectively, with an analytical linear range from 5 to 200 nM of FbpA.12Flow Cytometry62.95 nMBiosensorMagnetic Bead (MB)-based Protein SELEXATTO647N-labeledN/AN/ABest CandidateN/AN/A
ABdb_0831 295945922017Selection of DNA aptamers against Mycobacterium tuberculosis Ag85A, and its application in a graphene oxide-based fluorometric assayApt8GCTGTGTGACTCCTGCAA-TCAGGAAAGAACTTAGGGGTGGGAGGAGGGTATAAATACGGAAT-GCAGCTGTATCTTGTCTCC815'-GCTGTGTGACTCCTGCAA-N43-GCAGCTGTATCTTGTCTCC-3'ssDNAMycobacterium Tuberculosis (M.Tb.)Antigen 85 (Ag85A) (FbpA)Identify aptamers that bind to and develop a graphene oxide-based fluorometric assay to detect FbpA.N/A12Flow Cytometry202 nMBiosensorMagnetic Bead (MB)-based Protein SELEXATTO647N-labeledN/AN/AN/AN/AN/A