AptBacterialDB

Modification : Phenol-modified dUTP (dU^yTP)

Total records found: 12

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AptBacDB_ID ⇅ PMID/DOI ⇅ Year ⇅ Title ⇅ Aptamer name ⇅ Sequence (5′ to 3′) ⇅ Length ⇅ Library ⇅ Type ⇅ Target Organism ⇅ Target ⇅ Objective/Mechanism ⇅ Outcome/Inhibitory effect ⇅ No. of selection round SELEX ⇅ Determination of affinity method ⇅ Kd value ⇅ Activity Role ⇅ Method ⇅ Modification ⇅ Cytotoxicity (cell viability) ⇅ Stability⇅ Potential Candidate ⇅ Half-life ⇅ Patent ⇅
ABdb_0935 280099142017Whole cell-SELEX of aptamers with a tyrosine-like side chain against live bacteria8.1AGCGC(U^y)CGCGCGGCG(U^y)GC-ACAACAAA(U^y)G(U^y)GACCA(U^y)GCGA(U^y)(U^y)CCCCA(U^y)A(U^y)CCAGGCACA-C(U^y)G(U^y)(U^y)GGCGCAGGCCGACGC775'-GCGCTCGCGCGGCGTGC-40N-CTGTTGGCGCAGGCCGACGC-3'ssDNAEscherichia Coli (E. Coli) DH5αWhole cellIdentify modified aptamers that were isolated against Escherichia coli DH5α cells.N/A12Saturation Binding AssayN/ADetectionWhole Cell-SELEXPhenol-modified dUTP (dU^yTP)N/AN/AN/AN/AN/A
ABdb_0936 280099142017Whole cell-SELEX of aptamers with a tyrosine-like side chain against live bacteria8.2AGCGC(U^y)CGCGCGGCG(U^y)GC-GA(U^y)GCG(U^y)G(U^y)GG(U^y)G(U^y)GGAG(U^y)(U^y)G(U^y)G(U^y)GAG(U^y)GG(U^y)C(U^y)GCG(U^y)(U^y)G(U^y)-C(U^y)G(U^y)(U^y)GGCGCAGGCCGACGC775'-GCGCTCGCGCGGCGTGC-40N-CTGTTGGCGCAGGCCGACGC-3'ssDNAEscherichia Coli (E. Coli) DH5αWhole cellIdentify modified aptamers that were isolated against Escherichia coli DH5α cells.N/A12Saturation Binding AssayN/ADetectionWhole Cell-SELEXPhenol-modified dUTP (dU^yTP)N/AN/AN/AN/AN/A
ABdb_0937 280099142017Whole cell-SELEX of aptamers with a tyrosine-like side chain against live bacteria8.5BGCGC(U^y)CGCGCGGCG(U^y)GC-(U^y)(U^y)CA(U^y)GCCC(U^y)G(U^y)G(U^y)C(U^y)(U^y)GC(U^y)C(U^y)(U^y)G(U^y)GAG(U^y)(U^y)G(U^y)(U^y)G(U^y)G(U^y)CA-C(U^y)G(U^y)(U^y)GGCGCAGGCCGACGC765'-GCGCTCGCGCGGCGTGC-40N-CTGTTGGCGCAGGCCGACGC-3'ssDNAEscherichia Coli (E. Coli) DH5αWhole cellIdentify modified aptamers that were isolated against Escherichia coli DH5α cells.N/A12Saturation Binding AssayN/ADetectionWhole Cell-SELEXPhenol-modified dUTP (dU^yTP)N/AN/AN/AN/AN/A
ABdb_0938 280099142017Whole cell-SELEX of aptamers with a tyrosine-like side chain against live bacteria8.8AGCGC(U^y)CGCGCGGCG(U^y)GC-G(U^y)G(U^y)G(U^y)A(U^y)GCG(U^y)(U^y)CA(U^y)G(U^y)GG(U^y)GAGG(U^y)C(U^y)(U^y)GCG(U^y)C(U^y)G(U^y)(U^y)(U^y)-C(U^y)G(U^y)(U^y)GGCGCAGGCCGACGC765'-GCGCTCGCGCGGCGTGC-40N-CTGTTGGCGCAGGCCGACGC-3'ssDNAEscherichia Coli (E. Coli) DH5αWhole cellIdentify modified aptamers that were isolated against Escherichia coli DH5α cells.N/A12Saturation Binding AssayN/ADetectionWhole Cell-SELEXPhenol-modified dUTP (dU^yTP)N/AN/AN/AN/AN/A
ABdb_0939 280099142017Whole cell-SELEX of aptamers with a tyrosine-like side chain against live bacteria8.10AGCGC(U^y)CGCGCGGCG(U^y)GC-GAG(U^y)G(U^y)G(U^y)G(U^y)GGG(U^y)CCGAG(U^y)GGG(U^y)GG(U^y)CAGGG(U^y)(U^y)(U^y)G(U^y)(U^y)(U^y)-C(U^y)G(U^y)(U^y)GGCGCAGGCCGACGC765'-GCGCTCGCGCGGCGTGC-40N-CTGTTGGCGCAGGCCGACGC-3'ssDNAEscherichia Coli (E. Coli) DH5αWhole cellIdentify modified aptamers that were isolated against Escherichia coli DH5α cells.Showed the highest % binding to the DH5α cells, with per cent bound ranging from 2.9 to 21%.12Saturation Binding AssayN/ADetectionWhole Cell-SELEXPhenol-modified dUTP (dU^yTP)N/AN/AN/AN/AN/A
ABdb_0940 280099142017Whole cell-SELEX of aptamers with a tyrosine-like side chain against live bacteria8.14BGCGC(U^y)CGCGCGGCG(U^y)GC-(U^y)C(U^y)G(U^y)G(U^y)GCGG(U^y)G(U^y)(U^y)A(U^y)GCGGG(U^y)(U^y)GGG(U^y)(U^y)G(U^y)(U^y)(U^y)G(U^y)G(U^y)(U^y)(U^y)-C(U^y)G(U^y)(U^y)GGCGCAGGCCGACGC765'-GCGCTCGCGCGGCGTGC-40N-CTGTTGGCGCAGGCCGACGC-3'ssDNAEscherichia Coli (E. Coli) DH5αWhole cellIdentify modified aptamers that were isolated against Escherichia coli DH5α cells.Showed the highest % binding to the DH5α cells, with per cent bound ranging from 2.9 to 21%.12Saturation Binding AssayN/ADetectionWhole Cell-SELEXPhenol-modified dUTP (dU^yTP)N/AN/AN/AN/AN/A
ABdb_0941 280099142017Whole cell-SELEX of aptamers with a tyrosine-like side chain against live bacteria8.16BGCGC(U^y)CGCGCGGCG(U^y)GC-(U^y)(U^y)(U^y)GCG(U^y)CCGGG(U^y)(U^y)(U^y)A(U^y)GCGGG(U^y)(U^y)G(U^y)C(U^y)CG(U^y)G(U^y)C(U^y)G(U^y)(U^y)(U^y)-C(U^y)G(U^y)(U^y)GGCGCAGGCCGACGC765'-GCGCTCGCGCGGCGTGC-40N-CTGTTGGCGCAGGCCGACGC-3'ssDNAEscherichia Coli (E. Coli) DH5αWhole cellIdentify modified aptamers that were isolated against Escherichia coli DH5α cells.N/A12Saturation Binding AssayN/ADetectionWhole Cell-SELEXPhenol-modified dUTP (dU^yTP)N/AN/AN/AN/AN/A
ABdb_0942 280099142017Whole cell-SELEX of aptamers with a tyrosine-like side chain against live bacteria8.17BGCGC(U^y)CGCGCGGCG(U^y)GC-(U^y)C(U^y)(U^y)G(U^y)(U^y)GGG(U^y)CGACGG(U^y)C(U^y)G(U^y)(U^y)CA(U^y)G(U^y)GGG(U^y)G(U^y)(U^y)G(U^y)CCC-C(U^y)G(U^y)(U^y)GGCGCAGGCCGACGC775'-GCGCTCGCGCGGCGTGC-40N-CTGTTGGCGCAGGCCGACGC-3'ssDNAEscherichia Coli (E. Coli) DH5αWhole cellIdentify modified aptamers that were isolated against Escherichia coli DH5α cells.N/A12Saturation Binding AssayN/ADetectionWhole Cell-SELEXPhenol-modified dUTP (dU^yTP)N/AN/AN/AN/AN/A
ABdb_0943 280099142017Whole cell-SELEX of aptamers with a tyrosine-like side chain against live bacteria8.18BGCGC(U^y)CGCGCGGCG(U^y)GC-(U^y)(U^y)G(U^y)G(U^y)(U^y)CACG(U^y)CA(U^y)(U^y)(U^y)CGCAC(U^y)CC(U^y)C(U^y)CAGC(U^y)ACG(U^y)(U^y)(U^y)(U^y)-C(U^y)G(U^y)(U^y)GGCGCAGGCCGACGC775'-GCGCTCGCGCGGCGTGC-40N-CTGTTGGCGCAGGCCGACGC-3'ssDNAEscherichia Coli (E. Coli) DH5αWhole cellIdentify modified aptamers that were isolated against Escherichia coli DH5α cells.Showed the highest % binding to the DH5α cells, with per cent bound ranging from 2.9 to 21%.12Saturation Binding AssayN/ADetectionWhole Cell-SELEXPhenol-modified dUTP (dU^yTP)N/AN/AN/AN/AN/A
ABdb_0944 280099142017Whole cell-SELEX of aptamers with a tyrosine-like side chain against live bacteria8.24AGCGC(U^y)CGCGCGGCG(U^y)GC-(U^y)G(U^y)G(U^y)(U^y)(U^y)G(U^y)GG(U^y)ACGAGCG(U^y)G(U^y)G(U^y)GGA(U^y)GG(U^y)CCG(U^y)G(U^y)CA-C(U^y)G(U^y)(U^y)GGCGCAGGCCGACGC765'-GCGCTCGCGCGGCGTGC-40N-CTGTTGGCGCAGGCCGACGC-3'ssDNAEscherichia Coli (E. Coli) DH5αWhole cellIdentify modified aptamers that were isolated against Escherichia coli DH5α cells.N/A12Saturation Binding AssayN/ADetectionWhole Cell-SELEXPhenol-modified dUTP (dU^yTP)N/AN/AN/AN/AN/A
ABdb_0945 280099142017Whole cell-SELEX of aptamers with a tyrosine-like side chain against live bacteria8.28AGCGC(U^y)CGCGCGGCG(U^y)GC-(U^y)CC(U^y)CGCG(U^y)(U^y)(U^y)GGA(U^y)(U^y)CA(U^y)G(U^y)(U^y)GG(U^y)(U^y)(U^y)G(U^y)CGG(U^y)G(U^y)A(U^y)(U^y)G(U^y)-C(U^y)G(U^y)(U^y)GGCGCAGGCCGACGC775'-GCGCTCGCGCGGCGTGC-40N-CTGTTGGCGCAGGCCGACGC-3'ssDNAEscherichia Coli (E. Coli) DH5αWhole cellIdentify modified aptamers that were isolated against Escherichia coli DH5α cells.Showed the highest % binding to the DH5α cells, with per cent bound ranging from 2.9 to 21%.12Saturation Binding Assay27.4 ± 18.7 nMDetectionWhole Cell-SELEXPhenol-modified dUTP (dU^yTP) and Radiolabelled ([γ-32P]-labeled)N/AN/ABest CandidateN/AN/A
ABdb_0946 280099142017Whole cell-SELEX of aptamers with a tyrosine-like side chain against live bacteria8.30AGCGC(U^y)CGCGCGGCG(U^y)GC-ACAGAAAG(U^y)G(U^y)GGCCA(U^y)G(U^y)G(U^y)(U^y)G(U^y)G(U^y)CCC(U^y)GGCAGG(U^y)(U^y)AG(U^y)(U^y)(U^y)A-C(U^y)G(U^y)(U^y)GGCGCAGGCCGACGC815'-GCGCTCGCGCGGCGTGC-40N-CTGTTGGCGCAGGCCGACGC-3'ssDNAEscherichia Coli (E. Coli) DH5αWhole cellIdentify modified aptamers that were isolated against Escherichia coli DH5α cells.N/A12Saturation Binding AssayN/ADetectionWhole Cell-SELEXPhenol-modified dUTP (dU^yTP)N/AN/AN/AN/AN/A