Modification : FAM Labeled and Thiolated

Total records found: 2

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AptBacDB_ID ⇅	PMID/DOI ⇅	Year ⇅	Title ⇅	Aptamer name ⇅	Sequence (5′ to 3′) ⇅	Length ⇅	Library ⇅	Type ⇅	Target Organism ⇅	Target ⇅	Objective/Mechanism ⇅	Outcome/Inhibitory effect ⇅	No. of selection round SELEX ⇅	Determination of affinity method ⇅	Kd value ⇅	Activity Role ⇅	Method ⇅	Modification ⇅	Cytotoxicity (cell viability) ⇅	Stability⇅	Potential Candidate ⇅	Half-life ⇅	Patent ⇅
ABdb_1629	36005012	2022	Electrochemical Aptasensor for the Detection of the Key Virulence Factor YadA of Yersinia enterocolitica	Apt1	ATCCAGAGTGACGCAGCA-TGACAGACGGGAGAGACACGACGGGGGCGGGGAGTGAGAAGCGCGCGCTG-AATGTCGTTGGTGGCCC	85	5'-ATCCAGAGTGACGCAGCA-N50-AATGTCGTTGGTGGCCC-3'	ssDNA	Yersinia Enterocolitica (WA-314)	Virulence factor Yersinia adhesin A (YadA)	Identify an aptamer against YadA and develop an electrochemical biosensor for its detection.	Display a linear range between 7.0 × 10(4) and 7.0 × 10(7) CFU/mL, and the limit of detection of SWV was 7.0 × 10(4) CFU/mL.	8	Fluorescence Spectroscopy	11 nM	Biosensor	Whole Cell-SELEX	FAM Labeled and Thiolated	N/A	N/A	Best Candidate	N/A	N/A
ABdb_1749	36829672	2023	Aptasensor for the Detection of Moraxella catarrhalis Adhesin UspA2	Apt1_RC	ATCCAGAGTGACGCAGCA-GCGGCAGCCACCCAACGACCACGCTCATCCTCCTCCCCCGCACCGTCCCA-AATGTCGTTGGTGGCCC	85	5'-ATCCAGAGTGACGCAGCA-N50-AATGTCGTTGGTGGCCC-3'	ssDNA	Moraxella Catarrhalis (Bc5)	Ubiquitous Surface Protein A2 (UspA2)	Identify aptamers against and develop an electrochemical biosensor functionalized with an aptamer as a bioreceptor to detect UspA2.	Using SWV, exhibiting a linear detection range of 4.0 × 10(4)–7.0 × 10(7) CFU/mL, and a limit of detection of 4.0 × 10(4) CFU/mL at pH 5.0.	8	Fluorescence Spectroscopy	3.4 nM	Biosensor	Whole Cell-SELEX	FAM Labeled and Thiolated	N/A	N/A	Best Candidate	N/A	N/A