Modification : Carboxyfluorescein-GGGCCC at the 5' and 3' ends

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AptBacDB_ID ⇅ PMID/DOI ⇅ Year ⇅ Title ⇅ Aptamer name ⇅ Sequence (5′ to 3′) ⇅ Length ⇅ Library ⇅ Type ⇅ Target Organism ⇅ Target ⇅ Objective/Mechanism ⇅ Outcome/Inhibitory effect ⇅ No. of selection round SELEX ⇅ Determination of affinity method ⇅ Kd value ⇅ Activity Role ⇅ Method ⇅ Modification ⇅ Cytotoxicity (cell viability) ⇅ Stability⇅ Potential Candidate ⇅ Half-life ⇅ Patent ⇅
ABdb_0712 https://doi.org/10.1080/00032719.2015.10529742015Determination of Shigella flexneri by a Novel Fluorescent AptasensorAptamer1CCTCATGTCGAACAGCAACACTGCAACACTGTATAGTCCTGTGTGCCTTGAGCGTTTATTCTGAGCT67N/AssDNAShigella Flexneri (CGMCC 1.1868)Whole cellDeveloped a homogeneous fluorescent aptasensor using a dye-labelled aptamer and graphene oxide, using target recycling amplification for Shigella flexneri detection.A linear relationship was displayed from 500 to 10(9) CFU/mL with a limit of detection of 100 CFU/mL.N/AN/A29 ± 4 nMBiosensorN/ACarboxyfluorescein-GGGCCC at the 5' and 3' endsN/AN/AN/AN/AN/A