Modification : 5'-FAM Labeled and 3'-Amidation (NH₂)

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AptBacDB_ID ⇅ PMID/DOI ⇅ Year ⇅ Title ⇅ Aptamer name ⇅ Sequence (5′ to 3′) ⇅ Length ⇅ Library ⇅ Type ⇅ Target Organism ⇅ Target ⇅ Objective/Mechanism ⇅ Outcome/Inhibitory effect ⇅ No. of selection round SELEX ⇅ Determination of affinity method ⇅ Kd value ⇅ Activity Role ⇅ Method ⇅ Modification ⇅ Cytotoxicity (cell viability) ⇅ Stability⇅ Potential Candidate ⇅ Half-life ⇅ Patent ⇅
ABdb_0427 242800492014Aptamer cocktails: enhancement of sensing signals compared to single use of aptamers for detection of bacteriaE1GCAATGGTACGGTACTTCCACTTAGGTCGAGGTTAGTTTGTCTTGCTGGCGCATCCACTGAGCGCAAAAGTGCACGCTACTTTGCTAA88N/AssDNAEscherichia Coli (E. Coli) (KCTC 2571)Surface proteinDeveloped an aptamer cocktail with different components on the cell surface to enhance the sensing signal for bacterial detection.In electrochemical detection, the cocktail achieved an approximately 3.7 × 10^2 CFU/mL LOD (18-fold lower than the average single aptamer).N/AN/A12.4 nMBiosensorN/A5'-FAM Labeled and 3'-Amidation (NH₂)N/AN/AN/AN/AN/A
ABdb_0428 242800492014Aptamer cocktails: enhancement of sensing signals compared to single use of aptamers for detection of bacteriaE2GCAATGGTACGGTACTTCCCCATGAGTGTTGTGAAATGTTGGGACACTAGGTGGCATAGAGCCGCAAAAGTGCACGCTACTTTGCTAA88N/AssDNAEscherichia Coli (E. Coli) (KCTC 2571)Surface proteinDeveloped an aptamer cocktail with different components on the cell surface to enhance the sensing signal for bacterial detection.In electrochemical detection, the cocktail achieved an approximately 3.7 × 10^2 CFU/mL LOD (18-fold lower than the average single aptamer).N/AN/A25.2 nMBiosensorN/A5'-FAM Labeled and 3'-Amidation (NH₂)N/AN/AN/AN/AN/A
ABdb_0429 242800492014Aptamer cocktails: enhancement of sensing signals compared to single use of aptamers for detection of bacteriaE10GCAATGGTACGGTACTTCCGTTGCACTGTGCGGCCGAGCTGCCCCCTGGTTTGTGAATACCCTGGGCAAAAGTGCACGCTACTTTGCTAA90N/AssDNAEscherichia Coli (E. Coli) (KCTC 2571)Surface proteinDeveloped an aptamer cocktail with different components on the cell surface to enhance the sensing signal for bacterial detection.In electrochemical detection, the cocktail achieved an approximately 3.7 × 10^2 CFU/mL LOD (18-fold lower than the average single aptamer).N/AN/A14.2 nMBiosensorN/A5'-FAM Labeled and 3'-Amidation (NH₂)N/AN/AN/AN/AN/A