Modification : 5'-FAM Labeled, 5'-Thiolated and 5'-Amidation (NH₂)

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AptBacDB_ID ⇅	PMID/DOI ⇅	Year ⇅	Title ⇅	Aptamer name ⇅	Sequence (5′ to 3′) ⇅	Length ⇅	Library ⇅	Type ⇅	Target Organism ⇅	Target ⇅	Objective/Mechanism ⇅	Outcome/Inhibitory effect ⇅	No. of selection round SELEX ⇅	Determination of affinity method ⇅	Kd value ⇅	Activity Role ⇅	Method ⇅	Modification ⇅	Cytotoxicity (cell viability) ⇅	Stability⇅	Potential Candidate ⇅	Half-life ⇅	Patent ⇅
ABdb_1606	https://doi.org/10.1016/j.snb.2020.129100	2021	Naked eye colorimetric detection of Escherichia coli using aptamer conjugated graphene oxide enclosed Gold nanoparticles	E8	TAGGGAAGAGAAGGACATATGA-CATTCTGCACCGCCATCAGTCTTTCTTCGATACCGCGTTT-TTGACTAGTACATGACCACTTGA	85	5'-TAGGGAAGAGAAGGACATATGA-46N-TTGACTAGTACATGACCACTTGA-3'	ssDNA	Escherichia Coli (E. Coli) (MTCC no.1698)	Whole cell	Identify an aptamer against E.coli and develop a detection platform using gold nanoparticles and graphene oxide with aptamer conjugation.	The limit of detection observed visually was 10(2) cells/mL with GO coating and 10(3) cells/mL without GO. The detection limit in real-time coconut water samples was also 10(2) cells/mL.	7	Fluorescence Microplate Reader (Fluorescence Spectroscopy)	15.90 ± 3.07 nM	Biosensor	Whole Cell-SELEX	5'-FAM Labeled, 5'-Thiolated and 5'-Amidation (NH₂)	N/A	N/A	Best Candidate	N/A	N/A