AptBacterialDB

Modification : 5'-Biotinylated or FITC Labeled or Thiolated

Total records found: 4

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AptBacDB_ID ⇅ PMID/DOI ⇅ Year ⇅ Title ⇅ Aptamer name ⇅ Sequence (5′ to 3′) ⇅ Length ⇅ Library ⇅ Type ⇅ Target Organism ⇅ Target ⇅ Objective/Mechanism ⇅ Outcome/Inhibitory effect ⇅ No. of selection round SELEX ⇅ Determination of affinity method ⇅ Kd value ⇅ Activity Role ⇅ Method ⇅ Modification ⇅ Cytotoxicity (cell viability) ⇅ Stability⇅ Potential Candidate ⇅ Half-life ⇅ Patent ⇅
ABdb_0238 254361842013Molecular recognition of live methicillin-resistant staphylococcus aureus cells using DNA aptamersDTMRSA1ATCCAGACGTGACGCAGC-ATGCGGTTGGTTGCGGTTGGGCATGATGTATTTCTGTG-TGGACACGGTGGCTTAGTA755'-ATCCAGAGTGACGCAGCA-N40-TGGACACGGTGGCTTAGT-3'ssDNAMethicillin-resistant Staphylococcus aureus (MRSA)Whole cellIdentify aptamers against MRSA and conjugate them to AuNPs for their detection.DTMRSA1 and DTMRSA3 showed the best specificity for MRSA.17Flow Cytometry1.6 ± 0.5 × 10(2) nMDetectionWhole Cell-SELEX5'-Biotinylated or FITC Labeled or ThiolatedN/AN/ABest CandidateN/AN/A
ABdb_0239 254361842013Molecular recognition of live methicillin-resistant staphylococcus aureus cells using DNA aptamersDTMRSA2ATCCAGAGTGACGCAGCA-CGACACGTTAGGTTGGTTAGGTTGGTTAGTTTCTTG-TGGACACGGTGGCTTA705'-ATCCAGAGTGACGCAGCA-N40-TGGACACGGTGGCTTAGT-3'ssDNAMethicillin-resistant Staphylococcus aureus (MRSA)Whole cellIdentify aptamers against MRSA and conjugate them to AuNPs for their detection.DTMRSA2 and DTMRSA4 bound to all three types of clinical bacterial strains.17Flow Cytometry2.0 ± 0.6 × 10(2) nMDetectionWhole Cell-SELEX5'-Biotinylated or FITC Labeled or ThiolatedN/AN/AN/AN/AN/A
ABdb_0240 254361842013Molecular recognition of live methicillin-resistant staphylococcus aureus cells using DNA aptamersDTMRSA3ATCCAGAGTGACGCAGCA-GTAGATGGTTTGGTTGGTGTGGTTTCCTACTGATGTTGGG-TGGACACGGTGGCTTAGTA775'-ATCCAGAGTGACGCAGCA-N40-TGGACACGGTGGCTTAGT-3'ssDNAMethicillin-resistant Staphylococcus aureus (MRSA)Whole cellIdentify aptamers against MRSA and conjugate them to AuNPs for their detection.DTMRSA1 and DTMRSA3 showed the best specificity for MRSA.17Flow Cytometry1.3 ± 0.5 × 10(2) nMDetectionWhole Cell-SELEX5'-Biotinylated or FITC Labeled or ThiolatedN/AN/AN/AN/AN/A
ABdb_0241 254361842013Molecular recognition of live methicillin-resistant staphylococcus aureus cells using DNA aptamersDTMRSA4ATCCAGAGTGACGCAGCA-TTATGGGGTGTGGTGGGGGGTTAATGCGTTGGTTATCCG-TGTGGACACGGTGGCTTA755'-ATCCAGAGTGACGCAGCA-N40-TGGACACGGTGGCTTAGT-3'ssDNAMethicillin-resistant Staphylococcus aureus (MRSA)Whole cellIdentify aptamers against MRSA and conjugate them to AuNPs for their detection.DTMRSA2 and DTMRSA4 bound to all three types of clinical bacterial strains.17Flow Cytometry9.5 ± 2 × 10(1) nMDetectionWhole Cell-SELEX5'-Biotinylated or FITC Labeled or ThiolatedN/AN/AN/AN/AN/A