AptBacterialDB

Modification : 5'-Biotinylated (Biotin-(CH2)6)

Total records found: 4

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AptBacDB_ID ⇅ PMID/DOI ⇅ Year ⇅ Title ⇅ Aptamer name ⇅ Sequence (5′ to 3′) ⇅ Length ⇅ Library ⇅ Type ⇅ Target Organism ⇅ Target ⇅ Objective/Mechanism ⇅ Outcome/Inhibitory effect ⇅ No. of selection round SELEX ⇅ Determination of affinity method ⇅ Kd value ⇅ Activity Role ⇅ Method ⇅ Modification ⇅ Cytotoxicity (cell viability) ⇅ Stability⇅ Potential Candidate ⇅ Half-life ⇅ Patent ⇅
ABdb_0626 255627422015Aptamer-conjugated silver nanoparticles for electrochemical dual-aptamer-based sandwich detection of staphylococcus aureusPrimary anti-S.aureus aptamerTCCCTACGGCGCTAACCCCCCCAGTCCGTCCTCCCAGCCTCACACCGCCACCGTGCTACAAC62N/AssDNAStaphylococcus aureus (S. aureus) (ATCC 25923)Whole cellDual-aptamer-based sandwich immunosensor (Apt/S.aureus/apt-AgNP) for the detection of S. aureus.Display a dynamic range from 10 to 1×10(6) cfu/mL with a low detection limit of 1.0 cfu/mL.2N/A35 nMBiosensorWhole Cell-SELEX5'-Biotinylated (Biotin-(CH2)6)N/AN/AN/AN/AN/A
ABdb_1227 308778872019A new aptamer/polyadenylated DNA interdigitated gold electrode piezoelectric sensor for rapid detection of Pseudomonas aeruginosaP. aeruginosa aptamerCCCCCGTTGCTTTCGCTTTTCCTTTCGCTTTTGTTCGTTTCGTCCCTGCTTCCTTTCTTG60N/AssDNAPseudomonas Aeruginosa (ATCC 27853)Whole cellDeveloped a piezoelectric sensor (Au IDE-MSPQC) based on magnetic bead/aptamer/polyadenylated-DNA for the detection of P. aeruginosa.The limits of detection (LOD) of the method were as low as 9 CFU/mL in buffer and 52 CFU/mL in a simulated blood sample.N/AN/AN/ABiosensorN/A5'-Biotinylated (Biotin-(CH2)6)N/AN/AN/AN/AN/A
ABdb_1436 323506132020A fluorescent aptasensor for Staphylococcus aureus based on strand displacement amplification and self-assembled DNA hexagonal structureAptamerCACACCGCAGCAGTGGGAACGTTTCAGCCATGCAAGCATCACGCCCGT48N/AssDNAStaphylococcus aureus (S. aureus)Whole cellA fluorescent aptasensor based on MB-apt-cDNA duplex for S. aureus in milk samples.Exhibits a broad linear range from 7 to 7 × 10(7) CFU/mL, with a detection limit of 1.7 CFU/mL for S. aureus.N/AN/AN/ABiosensorN/A5'-Biotinylated (biotin-(CH2)6)N/AN/AN/AN/AN/A
ABdb_1718 360589392022Multiple amplification-based fluorometric aptasensor for highly sensitive detection of Staphylococcus aureusAptamerGCAATGGTACGGTACTTCCTCGGCACGTTCTCAGTAGCGCTCGCTGGTCATCCCACAGCTACGTCAAAAGTGCACGCTACTTTGCTAA88N/AssDNAStaphylococcus aureus (S. aureus) (ATCC 25923)Whole cellDeveloped a fluorometric aptasensor for the detection of S. aureus using magnetic nanoparticles (MNPs).The proposed fluorometric aptasensor displays LOD of (1.23 cfu/mL, a wide linear range (1 ~ 10(8) cfu/mL), and a fast detection speed (~ 1.5 h).N/AN/AN/ABiosensorN/A5'-Biotinylated (Biotin-(CH2)6)N/AN/AN/AN/AN/A