AptBacterialDB

Modification : 5'-Amidation (NH₂-(CH2)6) and 5'-Biotinylated

Total records found: 2

Download:

Search:
AptBacDB_ID ⇅ PMID/DOI ⇅ Year ⇅ Title ⇅ Aptamer name ⇅ Sequence (5′ to 3′) ⇅ Length ⇅ Library ⇅ Type ⇅ Target Organism ⇅ Target ⇅ Objective/Mechanism ⇅ Outcome/Inhibitory effect ⇅ No. of selection round SELEX ⇅ Determination of affinity method ⇅ Kd value ⇅ Activity Role ⇅ Method ⇅ Modification ⇅ Cytotoxicity (cell viability) ⇅ Stability⇅ Potential Candidate ⇅ Half-life ⇅ Patent ⇅
ABdb_0656 266360982015Selection of Single-Stranded DNA Molecular Recognition Elements against Exotoxin A Using a Novel Decoy-SELEX Method and Sensitive Detection of Exotoxin A in Human SerumR14.33TGTACCGTCTGAGCGATTCGTAC-CATAGGGTGCTTTTCAAGGCCACACGTTAGTGTA-AGCCAGTCAGTGTTAAGGAGTGC805'-TGTACCGTCTGAGCGATTCGTAC-34N-AGCCAGTCAGTGTTAAGGAGTGC-3'ssDNAPseudomonas AeruginosaExotoxin AIdentify ssDNA MREs against Exotoxin A and develop a sandwich ELISA for its detection in human serum.100 nM or 6.6 μg/mL of Exotoxin A in human serum was detected.14Surface Plasmon Resonance (SPR)4.2 and 4.5 μMDiagnosticDecoy-SELEX5'-Amidation (NH₂-(CH2)6) and 5'-BiotinylatedN/AN/ABest CandidateN/AN/A
ABdb_1903 413395962025Self-reduced Pd nanoparticles on NiMn-LDHs with superior catalytic activity for signal amplification in electrochemical aptasensing of Mycobacterium tuberculosis ESAT-6 antigenAptGGGAGCTCAGAATAAACGCTCAACCTCCCTGGGTCACCATAGACTCCATCTAAGATGCTTCGACATGAGGCCCGGATC78N/AssDNAMycobacterium Tuberculosis (M.Tb.)ESAT-6 (6-kDa early secretory antigenic target)Developed an electrochemical aptasensor using NiMn-layered double hydroxides@palladium nanoparticles (NiMn-LDHs@PdNPs) for detecting the ESAT-6 antigen in human serum.The aptasensor exhibited a wide linear detection range of 75 pg/mL to 10 ng/mL with a low limit of detection (LOD) of 0.629 pg/mL.N/AN/AN/ABiosensorN/A5'-Amidation (NH₂-(CH2)6) and 5'-BiotinylatedN/AAptasensor was stored at 4°C for and after 30 days, the current remained approximately 80% of the initial value.N/AN/AN/A