Modification : 3'-Fluorescein Labeled

Total records found: 6

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AptBacDB_ID ⇅	PMID/DOI ⇅	Year ⇅	Title ⇅	Aptamer name ⇅	Sequence (5′ to 3′) ⇅	Length ⇅	Library ⇅	Type ⇅	Target Organism ⇅	Target ⇅	Objective/Mechanism ⇅	Outcome/Inhibitory effect ⇅	No. of selection round SELEX ⇅	Determination of affinity method ⇅	Kd value ⇅	Activity Role ⇅	Method ⇅	Modification ⇅	Cytotoxicity (cell viability) ⇅	Stability⇅	Potential Candidate ⇅	Half-life ⇅	Patent ⇅
ABdb_0074	19234874	2009	Aptamer-based electrochemical biosensor for Botulinum neurotoxin	BoNT/A aptamer	ATACCAGCTTATTCAATTGACATGACTGGGATTTTTGGCGAAATCGAAGGAAGCGGAGAGATAGTAAGTGCAATCT	76	N/A	ssDNA	Clostridium Botulinum	Botulinum neurotoxins (BoNT)-light chain of type A (BoNT/A) toxoid	Developed an aptamer-based electrochemical sensor for the detection of Botulinum neurotoxin.	Achieved a limit of detection (LOD) of 40 pg/ml within 24 h.	N/A	N/A	3.0 ± 0.8 × 10(9) M−1	Biosensor	Single micro-bead SELEX	5'-Biotinylated and 3'-Fluorescein Labeled	N/A	N/A	N/A	N/A	N/A
ABdb_0317	23357235	2013	Isolation and characterization of DNA aptamers against Escherichia coli using a bacterial cell-systematic evolution of ligands by exponential enrichment approach	E1	GCAATGGTACGGTACTTCC-ACTTAGGTCGAGGTTAGTTTGTCTTGCTGGCGCATCCACTGAGCG-CAAAAGTGCACGCTACTTTGCTAA	88	5'-GCAATGGTACGGTACTTCC-N45-CAAAAGTGCACGCTACTTTGCTAA-3'	ssDNA	Escherichia Coli (E. Coli) (KCTC 2571)	Whole cell	Isolated and characterized aptamers against Escherichia coli.	Display binding ranging from 42.6% to 131.8% to E. coli.	10	Fluorescence Spectroscopy	12.4 nM	Detection	Whole Cell-SELEX	3'-Fluorescein Labeled	N/A	N/A	N/A	N/A	N/A
ABdb_0318	23357235	2013	Isolation and characterization of DNA aptamers against Escherichia coli using a bacterial cell-systematic evolution of ligands by exponential enrichment approach	E2	GCAATGGTACGGTACTTCC-CCATGAGTGTTGTGAAATGTTGGGACACTAGGTGGCATAGAGCCG-CAAAAGTGCACGCTACTTTGCTAA	88	5'-GCAATGGTACGGTACTTCC-N45-CAAAAGTGCACGCTACTTTGCTAA-3'	ssDNA	Escherichia Coli (E. Coli) (KCTC 2571)	Whole cell	Isolated and characterized aptamers against Escherichia coli.	Display binding ranging from 42.6% to 131.8% to E. coli.	10	Fluorescence Spectroscopy	25.2 nM	Detection	Whole Cell-SELEX	3'-Fluorescein Labeled	N/A	N/A	N/A	N/A	N/A
ABdb_0319	23357235	2013	Isolation and characterization of DNA aptamers against Escherichia coli using a bacterial cell-systematic evolution of ligands by exponential enrichment approach	E10	GCAATGGTACGGTACTTCC-GTTGCACTGTGCGGCCGAGCTGCCCCCTGGTTTGTGAATACCCTGGG-CAAAAGTGCACGCTACTTTGCTAA	90	5'-GCAATGGTACGGTACTTCC-N45-CAAAAGTGCACGCTACTTTGCTAA-3'	ssDNA	Escherichia Coli (E. Coli) (KCTC 2571)	Whole cell	Isolated and characterized aptamers against Escherichia coli.	Display binding ranging from 42.6% to 131.8% to E. coli.	10	Fluorescence Spectroscopy	14.2 nM	Detection	Whole Cell-SELEX	3'-Fluorescein Labeled	N/A	N/A	N/A	N/A	N/A
ABdb_0320	23357235	2013	Isolation and characterization of DNA aptamers against Escherichia coli using a bacterial cell-systematic evolution of ligands by exponential enrichment approach	E12	GCAATGGTACGGTACTTCC-GCGAGGGCCAACGGTGGTTACGTCGCTACGGCGCTACTGGTTGAT-CAAAAGTGCACGCTACTTTGCTAA	88	5'-GCAATGGTACGGTACTTCC-N45-CAAAAGTGCACGCTACTTTGCTAA-3'	ssDNA	Escherichia Coli (E. Coli) (KCTC 2571)	Whole cell	Isolated and characterized aptamers against Escherichia coli.	Display binding ranging from 42.6% to 131.8% to E. coli.	10	Fluorescence Spectroscopy	16.8 nM	Detection	Whole Cell-SELEX	3'-Fluorescein Labeled	N/A	N/A	N/A	N/A	N/A
ABdb_0789	26592593	2016	Chemiluminescent aptasensor capable of rapidly quantifying Escherichia Coli O157:H7	EA1	CCGGACGCTTATGCCTTGCCATCTACAGAGCAGGTGTGACGG	42	N/A	ssDNA	Escherichia Coli (E. Coli) O157:H7	Whole cell	Develop aptamer conjugated graphene oxide (GO)/iron nanocomposites for guanine chemiluminescence detection of E. Coli O157:H7.	N/A	N/A	N/A	N/A	Biosensor	N/A	3'-Fluorescein Labeled	N/A	N/A	N/A	N/A	N/A