Modification : 3'-Amidation (NH₂-(CH2)7)

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AptBacDB_ID ⇅ PMID/DOI ⇅ Year ⇅ Title ⇅ Aptamer name ⇅ Sequence (5′ to 3′) ⇅ Length ⇅ Library ⇅ Type ⇅ Target Organism ⇅ Target ⇅ Objective/Mechanism ⇅ Outcome/Inhibitory effect ⇅ No. of selection round SELEX ⇅ Determination of affinity method ⇅ Kd value ⇅ Activity Role ⇅ Method ⇅ Modification ⇅ Cytotoxicity (cell viability) ⇅ Stability⇅ Potential Candidate ⇅ Half-life ⇅ Patent ⇅
ABdb_0809 274117752016Rapid and Selective Detection of Pathogenic Bacteria in Bloodstream Infections with Aptamer-Based RecognitionApt-S. aureusTCCCTACGGCGCTAACCCCCCCAGTCCGTCCTCCCAGCCTCACACCGCCACCGTGCTACAACTTTTTTTTT71N/AssDNAStaphylococcus aureus (S. aureus)Whole cellAptamer-based capture platform using Fe3O4@mTiO2 magnetic nanoparticles for the detection of bacteria.Display a favourable bacterial-capture efficiency of about 80% even at low infectious doses (10–2000 CFU/mL).N/AN/AN/ADetectionN/A3'-Amidation (NH₂-(CH2)7) and 3'-FAM Labeled ((CH2)7-FAM)N/AN/AN/AN/AN/A
ABdb_0810 274117752016Rapid and Selective Detection of Pathogenic Bacteria in Bloodstream Infections with Aptamer-Based RecognitionApt-E. coliATCCGTCACACCTGCTCTACTGGCCGGCTCAGCATGACTAAGAAGGAAGTTATGTGGTGTTGGCTCCCGTATTTTTTTTTT81N/AssDNAEscherichia Coli (E. Coli)Whole cellAptamer-based capture platform using Fe3O4@mTiO2 magnetic nanoparticles for the detection of bacteria.Display a favourable bacterial-capture efficiency of about 80% even at low infectious doses (10–2000 CFU/mL).N/AN/AN/ADetectionN/A3'-Amidation (NH₂-(CH2)7)N/AN/AN/AN/AN/A