AptBacterialDB

Method : NECEEM-based non-SELEX

Total records found: 10

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AptBacDB_ID ⇅ PMID/DOI ⇅ Year ⇅ Title ⇅ Aptamer name ⇅ Sequence (5′ to 3′) ⇅ Length ⇅ Library ⇅ Type ⇅ Target Organism ⇅ Target ⇅ Objective/Mechanism ⇅ Outcome/Inhibitory effect ⇅ No. of selection round SELEX ⇅ Determination of affinity method ⇅ Kd value ⇅ Activity Role ⇅ Method ⇅ Modification ⇅ Cytotoxicity (cell viability) ⇅ Stability⇅ Potential Candidate ⇅ Half-life ⇅ Patent ⇅
ABdb_0147 223702802012Harnessing aptamers for electrochemical detection of endotoxinB1CTTCTGCCCGCCTCCTTCC-TAGCCGGATCGCGCTGGCCAGATGATATAAAGGGTCAACCCCCCA-GGAGACGAGATAGGCGGACACT865'-CTTCTGCCCGCCTCCTTCC-45N-GGAGACGAGATAGGCGGACACT-3'ssDNAEscherichia Coli (E. Coli) 055:B5 (L4524)Lipopolysaccharide (LPS)Identify aptamers showing specific affinity to LPS and develop an electrochemical aptasensor on a gold surface for its detection.Achieved a linear detection range of 0.01 to 1 ng/mL of LPS with a detection time of less than 15 minutes.3Surface Plasmon Resonance (SPR)20 nMBiosensorNECEEM-based non-SELEX5'-Thiolated (HS-(CH2)6)N/AN/AN/AN/AN/A
ABdb_0148 223702802012Harnessing aptamers for electrochemical detection of endotoxinB2CTTCTGCCCGCCTCCTTCC-TAGCCGGATCGCGCTGGCCAGATGATATAAAGGGTCAGCCCCCCA-GGAGACGAGATAGGCGGACACT865'-CTTCTGCCCGCCTCCTTCC-45N-GGAGACGAGATAGGCGGACACT-3'ssDNAEscherichia Coli (E. Coli) 055:B5 (L4524)Lipopolysaccharide (LPS)Identify aptamers showing specific affinity to LPS and develop an electrochemical aptasensor on a gold surface for its detection.N/A3Surface Plasmon Resonance (SPR)12 nMBiosensorNECEEM-based non-SELEX5'-Thiolated (HS-(CH2)6)N/AN/ABest CandidateN/AN/A
ABdb_0149 223702802012Harnessing aptamers for electrochemical detection of endotoxinB3CTTCTGCCCGCCTCCTTCC-TAGCCGGATCGCGTTGGCCAGATGATATAAAGGGTCAACCCCCCA-GGAGACGAGATAGGCGGACACT865'-CTTCTGCCCGCCTCCTTCC-45N-GGAGACGAGATAGGCGGACACT-3'ssDNAEscherichia Coli (E. Coli) 055:B5 (L4524)Lipopolysaccharide (LPS)Identify aptamers showing specific affinity to LPS and develop an electrochemical aptasensor on a gold surface for its detection.N/A3Surface Plasmon Resonance (SPR)32 nMBiosensorNECEEM-based non-SELEX5'-Thiolated (HS-(CH2)6)N/AN/AN/AN/AN/A
ABdb_0150 223702802012Harnessing aptamers for electrochemical detection of endotoxinB4CTTCTGCCCGCCTCCTTCC-TAGCCGGATCGCGCTGGCCAGATGATATAAAGGGTCAACCCCCCG-GGAGACGAGATAGGCGGACACT865'-CTTCTGCCCGCCTCCTTCC-45N-GGAGACGAGATAGGCGGACACT-3'ssDNAEscherichia Coli (E. Coli) 055:B5 (L4524)Lipopolysaccharide (LPS)Identify aptamers showing specific affinity to LPS and develop an electrochemical aptasensor on a gold surface for its detection.N/A3Surface Plasmon Resonance (SPR)21 nMBiosensorNECEEM-based non-SELEX5'-Thiolated (HS-(CH2)6)N/AN/AN/AN/AN/A
ABdb_0151 223702802012Harnessing aptamers for electrochemical detection of endotoxinB5CTTCTGCCCGCCTCCTTCC-CTAAGCACAGGGAAACCAGCTAATGAGTTAGGCCTGTCCCCCACG-GGAGACGAGATAGGCGGACACT865'-CTTCTGCCCGCCTCCTTCC-45N-GGAGACGAGATAGGCGGACACT-3'ssDNAEscherichia Coli (E. Coli) 055:B5 (L4524)Lipopolysaccharide (LPS)Identify aptamers showing specific affinity to LPS and develop an electrochemical aptasensor on a gold surface for its detection.N/A3Surface Plasmon Resonance (SPR)484 nMBiosensorNECEEM-based non-SELEX5'-Thiolated (HS-(CH2)6)N/AN/AN/AN/AN/A
ABdb_0152 223702802012Harnessing aptamers for electrochemical detection of endotoxinB6CTTCTGCCCGCCTCCTTCC-CAATGGACCTATTCGAGTACTGAATAGAACAGTCGGCGCTCTGGG-GGAGACGAGATAGGCGGACACT865'-CTTCTGCCCGCCTCCTTCC-45N-GGAGACGAGATAGGCGGACACT-3'ssDNAEscherichia Coli (E. Coli) 055:B5 (L4524)Lipopolysaccharide (LPS)Identify aptamers showing specific affinity to LPS and develop an electrochemical aptasensor on a gold surface for its detection.N/A3Surface Plasmon Resonance (SPR)298 nMBiosensorNECEEM-based non-SELEX5'-Thiolated (HS-(CH2)6)N/AN/AN/AN/AN/A
ABdb_0153 223702802012Harnessing aptamers for electrochemical detection of endotoxinB7CTTCTGCCCGCCTCCTTCC-TTCAAGACGATGCCTGGCGCGAGTTACACACTTGCATGGAGCTGG-GGAGACGAGATAGGCGGACACT865'-CTTCTGCCCGCCTCCTTCC-45N-GGAGACGAGATAGGCGGACACT-3'ssDNAEscherichia Coli (E. Coli) 055:B5 (L4524)Lipopolysaccharide (LPS)Identify aptamers showing specific affinity to LPS and develop an electrochemical aptasensor on a gold surface for its detection.N/A3Surface Plasmon Resonance (SPR)61 nMBiosensorNECEEM-based non-SELEX5'-Thiolated (HS-(CH2)6)N/AN/AN/AN/AN/A
ABdb_0154 223702802012Harnessing aptamers for electrochemical detection of endotoxinB8CTTCTGCCCGCCTCCTTCC-ATCCAATACCTCAGAACTCAGTTCGAGTCGTAAAGGGGAATCGCA-GGAGACGAGATAGGCGGACACT865'-CTTCTGCCCGCCTCCTTCC-45N-GGAGACGAGATAGGCGGACACT-3'ssDNAEscherichia Coli (E. Coli) 055:B5 (L4524)Lipopolysaccharide (LPS)Identify aptamers showing specific affinity to LPS and develop an electrochemical aptasensor on a gold surface for its detection.N/A3Surface Plasmon Resonance (SPR)71 nMBiosensorNECEEM-based non-SELEX5'-Thiolated (HS-(CH2)6)N/AN/AN/AN/AN/A
ABdb_0155 223702802012Harnessing aptamers for electrochemical detection of endotoxinB9CTTCTGCCCGCCTCCTTCC-ACCGATCCATCGAGTTTCTGAGAAAGGCCCGGAGAAACCGCGAGA-GGAGACGAGATAGGCGGACACT865'-CTTCTGCCCGCCTCCTTCC-45N-GGAGACGAGATAGGCGGACACT-3'ssDNAEscherichia Coli (E. Coli) 055:B5 (L4524)Lipopolysaccharide (LPS)Identify aptamers showing specific affinity to LPS and develop an electrochemical aptasensor on a gold surface for its detection.N/A3Surface Plasmon Resonance (SPR)15 nMBiosensorNECEEM-based non-SELEX5'-Thiolated (HS-(CH2)6)N/AN/AN/AN/AN/A
ABdb_0156 223702802012Harnessing aptamers for electrochemical detection of endotoxinB10CTTCTGCCCGCCTCCTTCC-TCAATCTAACCATGCATGCAGTTTAGGCAGGATTCGTTATCGCAA-GGAGACGAGATAGGCGGACACT865'-CTTCTGCCCGCCTCCTTCC-45N-GGAGACGAGATAGGCGGACACT-3'ssDNAEscherichia Coli (E. Coli) 055:B5 (L4524)Lipopolysaccharide (LPS)Identify aptamers showing specific affinity to LPS and develop an electrochemical aptasensor on a gold surface for its detection.N/A3Surface Plasmon Resonance (SPR)2336 nMBiosensorNECEEM-based non-SELEX5'-Thiolated (HS-(CH2)6)N/AN/AN/AN/AN/A