AptBacterialDB

Method : FluCell‐SELEX

Total records found: 7

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AptBacDB_ID ⇅ PMID/DOI ⇅ Year ⇅ Title ⇅ Aptamer name ⇅ Sequence (5′ to 3′) ⇅ Length ⇅ Library ⇅ Type ⇅ Target Organism ⇅ Target ⇅ Objective/Mechanism ⇅ Outcome/Inhibitory effect ⇅ No. of selection round SELEX ⇅ Determination of affinity method ⇅ Kd value ⇅ Activity Role ⇅ Method ⇅ Modification ⇅ Cytotoxicity (cell viability) ⇅ Stability⇅ Potential Candidate ⇅ Half-life ⇅ Patent ⇅
ABdb_1455 325158422020The Diversity of a Polyclonal FluCell‐SELEX Library Outperforms Individual Aptamers as Emerging Diagnostic Tools for the Identification of Carbapenem Resistant Pseudomonas aeruginosaC1R1TAGGGAAGAGAAGGACATATGAT-GCGCGCGAGATTAACCCCCCAATGCTGCACCGAGCCACGA-TCAAGTGGTCATGTACTAGTCAA865'-TAGGGAAGAGAAGGACATATGAT-40N-TCAAGTGGTCATGTACTAGTCAA-3'ssDNAPseudomonas Aeruginosa PAO1Outer membrane protein (OMP) OprF, OprM and OprDIdentify an aptamer library that specifically targets different clinically relevant strains, thereby inhibiting virulence-associated cellular functions.With 250 cells as the lowest measured cell number by the C1R1. The R16 aptamer library outperformed single aptamers in labelling and inhibiting biofilm and motility.16Fluorescence Spectroscopy31 ± 2 nMTherapeuticsFluCell‐SELEX5'-Cyanine5 (Cy5) LabeledN/AN/AN/AN/AN/A
ABdb_1456 325158422020The Diversity of a Polyclonal FluCell‐SELEX Library Outperforms Individual Aptamers as Emerging Diagnostic Tools for the Identification of Carbapenem Resistant Pseudomonas aeruginosaC2R1TAGGGAAGAGAAGGACATATGAT-GCGGCAGGGAAGGACTATGTGGGTGAAAGGAGTGCGCGGG-TCAAGTGGTCATGTACTAGTCAA865'-TAGGGAAGAGAAGGACATATGAT-40N-TCAAGTGGTCATGTACTAGTCAA-3'ssDNAPseudomonas Aeruginosa PAO1Outer membrane protein (OMP) OprF, OprM and OprDIdentify an aptamer library that specifically targets different clinically relevant strains, thereby inhibiting virulence-associated cellular functions.The R16 aptamer library outperformed single aptamers in labelling and inhibiting biofilm and motility.16Fluorescence SpectroscopyN/ATherapeuticsFluCell‐SELEX5'-Cyanine5 (Cy5) LabeledN/AN/AN/AN/AN/A
ABdb_1457 325158422020The Diversity of a Polyclonal FluCell‐SELEX Library Outperforms Individual Aptamers as Emerging Diagnostic Tools for the Identification of Carbapenem Resistant Pseudomonas aeruginosaC2R2TAGGGAAGAGAAGGACATATGAT-GCAGCGGGATGGGGTAAATGGTGGCGAGAGGCGTCGGGGG-TCAAGTGGTCATGTACTAGTCAA865'-TAGGGAAGAGAAGGACATATGAT-40N-TCAAGTGGTCATGTACTAGTCAA-3'ssDNAPseudomonas Aeruginosa PAO1Outer membrane protein (OMP) OprF, OprM and OprDIdentify an aptamer library that specifically targets different clinically relevant strains, thereby inhibiting virulence-associated cellular functions.The R16 aptamer library outperformed single aptamers in labelling and inhibiting biofilm and motility.16Fluorescence SpectroscopyN/ATherapeuticsFluCell‐SELEX5'-Cyanine5 (Cy5) LabeledN/AN/AN/AN/AN/A
ABdb_1458 325158422020The Diversity of a Polyclonal FluCell‐SELEX Library Outperforms Individual Aptamers as Emerging Diagnostic Tools for the Identification of Carbapenem Resistant Pseudomonas aeruginosaC4R2TAGGGAAGAGAAGGACATATGAT-GCGGGTTGACTAGTACATGACCACTTGAGTCGCTTGAACT-TCAAGTGGTCATGTACTAGTCAA865'-TAGGGAAGAGAAGGACATATGAT-40N-TCAAGTGGTCATGTACTAGTCAA-3'ssDNAPseudomonas Aeruginosa PAO1Outer membrane protein (OMP) OprF, OprM and OprDIdentify an aptamer library that specifically targets different clinically relevant strains, thereby inhibiting virulence-associated cellular functions.Labelling efficiency by C4R2 of approximately 60 % fluorescence signal relative to R16 values. The R16 aptamer library outperformed single aptamers in labelling and inhibiting biofilm and motility.16Fluorescence SpectroscopyN/ATherapeuticsFluCell‐SELEX5'-Cyanine5 (Cy5) LabeledN/AN/AN/AN/AN/A
ABdb_1459 325158422020The Diversity of a Polyclonal FluCell‐SELEX Library Outperforms Individual Aptamers as Emerging Diagnostic Tools for the Identification of Carbapenem Resistant Pseudomonas aeruginosaC6R3TAGGGAAGAGAAGGACATATGAT-GCGGGGAGAGGCGAAAGAAGCTGGGATGGAAGGGCGTAGG-TCAAGTGGTCATGTACTAGTCAA865'-TAGGGAAGAGAAGGACATATGAT-40N-TCAAGTGGTCATGTACTAGTCAA-3'ssDNAPseudomonas Aeruginosa PAO1Outer membrane protein (OMP) OprF, OprM and OprDIdentify an aptamer library that specifically targets different clinically relevant strains, thereby inhibiting virulence-associated cellular functions.The R16 aptamer library outperformed single aptamers in labelling and inhibiting biofilm and motility.16Fluorescence SpectroscopyN/ATherapeuticsFluCell‐SELEX5'-Cyanine5 (Cy5) LabeledN/AN/AN/AN/AN/A
ABdb_1460 325158422020The Diversity of a Polyclonal FluCell‐SELEX Library Outperforms Individual Aptamers as Emerging Diagnostic Tools for the Identification of Carbapenem Resistant Pseudomonas aeruginosaC10R5TAGGGAAGAGAAGGACATATGAT-GCAGCCACAGCAGAGACGGGAAGGGCCAGGGTTGAGCGGG-TCAAGTGGTCATGTACTAGTCAA865'-TAGGGAAGAGAAGGACATATGAT-40N-TCAAGTGGTCATGTACTAGTCAA-3'ssDNAPseudomonas Aeruginosa PAO1Outer membrane protein (OMP) OprF, OprM and OprDIdentify an aptamer library that specifically targets different clinically relevant strains, thereby inhibiting virulence-associated cellular functions.The R16 aptamer library outperformed single aptamers in labelling and inhibiting biofilm and motility.16Fluorescence SpectroscopyN/ATherapeuticsFluCell‐SELEX5'-Cyanine5 (Cy5) LabeledN/AN/AN/AN/AN/A
ABdb_1461 325158422020The Diversity of a Polyclonal FluCell‐SELEX Library Outperforms Individual Aptamers as Emerging Diagnostic Tools for the Identification of Carbapenem Resistant Pseudomonas aeruginosaC10R6TAGGGAAGAGAAGGACATATGAT-GCGGCGGTGGGGCTTTCGGTGATTTGGGCGGTTTGGCGGG-TCAAGTGGTCATGTACTAGTCAA865'-TAGGGAAGAGAAGGACATATGAT-40N-TCAAGTGGTCATGTACTAGTCAA-3'ssDNAPseudomonas Aeruginosa PAO1Outer membrane protein (OMP) OprF, OprM and OprDIdentify an aptamer library that specifically targets different clinically relevant strains, thereby inhibiting virulence-associated cellular functions.The R16 aptamer library outperformed single aptamers in labelling and inhibiting biofilm and motility.16Fluorescence SpectroscopyN/ATherapeuticsFluCell‐SELEX5'-Cyanine5 (Cy5) LabeledN/AN/AN/AN/AN/A