Welcome to AptBacterialDB
A comprehensive and manually curated database dedicated to antibacterial aptamers with experimentally validated activity against pathogenic bacteria.
About the Database
AptBacterialDB provides curated information on experimentally validated antibacterial aptamers. It contains 2,131 entries for 1,555 unique antibacterial aptamers consisting of DNA and RNA. Each entry includes detailed information about the aptamer sequence, target bacteria, binding affinity (Kd value), experimental methods, and relevant literature references.
Search Options
Basic Search — search across any or multiple fields with customizable display.
Advanced Search — combine queries with AND/OR/NOT logical operators.
Structure Search — search by secondary structure in dot-bracket notation.
Browse
Browse aptamers by type (DNA/RNA), target species, application, and experimental validation. Systematic exploration across bacterial classes and functional categories.
Responsive Design
Built on a responsive template compatible with desktop, tablet, and smartphone. The interface dynamically adjusts based on screen size.
2131
Total Entries
1555
Unique Aptamers
124
Unique Targets
500+
PMID / DOI
How It Works
Aptamers are short, single-stranded DNA or RNA molecules that bind targets with high specificity. AptBacterialDB integrates experimentally validated data, enabling systematic exploration of their binding behavior, target specificity, and potential antibacterial applications.
SELEX Selection
Aptamers are selected through Systematic Evolution of Ligands by Exponential Enrichment.
Learn about SELEX methods →Binding affinity
Each aptamer's binding affinity (Kd) is experimentally validated using techniques like SPR, ELONA, or flow cytometry.
Learn about Affinity determination methods →Literature Curation
All entries are manually curated from peer-reviewed publications with full citation tracking.