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H-(Hyp)-LLPPVPLFG details

Primary information
ID	antitb_1642,
Name	26213786
N-Terminal modification	Callyaerins 8
C-Terminal Modification	H-(Hyp)-LLPPVPLFG
Chemical Modification	Free
Linear/Cyclic	Amidation
Length	Hyp= Hydroxiproline, Residue 1-8 involved in cyclic bond formation
Chirality	Cyclic
Nature	11
Source	D
Origin	Cationic
Species	Natural
Strain	Derived from Callyspongia aerizusa
Inhibition Concentration	Mycobacterium Tuberculosis
In Vitro/ In vivo	Mycobacterium tuberculosis H37Rv
Cell Line	IC90= 40 Î¼g/ml
Inhibition Concentration	in vitro
Sequence	2015
Cytotoxicity	NA
In vivo Model	NA
Lethal Dose	NA
Immune Responce	NA
Mechanism of Action	NA
Target	NA
Combination Therapy	NA
Other activities	NA
PMID	NA
Year of Publication	NA
Tertiary Structure (Technique)	Not Predicted),

Primary information
ID	antitb_1643,
Name	26213786
N-Terminal modification	Callyaerins 8
C-Terminal Modification	H-(Hyp)-LLPPVPLFG
Chemical Modification	Free
Linear/Cyclic	Amidation
Length	Hyp= Hydroxiproline, Residue 1-8 involved in cyclic bond formation
Chirality	Cyclic
Nature	11
Source	D
Origin	Cationic
Species	Natural
Strain	Derived from Callyspongia aerizusa
Inhibition Concentration	Mycobacterium Tuberculosis
In Vitro/ In vivo	Mycobacterium tuberculosis H37Rv
Cell Line	MIC = 100 Î¼g/ml
Inhibition Concentration	in vitro
Sequence	2015
Cytotoxicity	NA
In vivo Model	NA
Lethal Dose	NA
Immune Responce	NA
Mechanism of Action	NA
Target	NA
Combination Therapy	NA
Other activities	NA
PMID	NA
Year of Publication	NA
Tertiary Structure (Technique)	Not Predicted),

Primary information
ID	antitb_1644,
Name	26213786
N-Terminal modification	Callyaerins 8
C-Terminal Modification	H-(Hyp)-LLPPVPLFG
Chemical Modification	Free
Linear/Cyclic	Amidation
Length	Hyp= Hydroxiproline, Residue 1-8 involved in cyclic bond formation
Chirality	Cyclic
Nature	11
Source	D
Origin	Cationic
Species	Natural
Strain	Derived from Callyspongia aerizusa
Cell Line	IC50= >100 Î¼g/ml
Inhibition Concentration	in vitro
Sequence	2015
Cytotoxicity	THP-1 cell line
In vivo Model	50% reduction in bacterial load
Lethal Dose	NA
Immune Responce	NA
Mechanism of Action	NA
Target	NA
Combination Therapy	NA
Other activities	NA
PMID	NA
Year of Publication	NA
Tertiary Structure (Technique)	Not Predicted),

Primary information
ID	antitb_1645,
Name	26213786
N-Terminal modification	Callyaerins 8
C-Terminal Modification	H-(Hyp)-LLPPVPLFG
Chemical Modification	Free
Linear/Cyclic	Amidation
Length	Hyp= Hydroxiproline, Residue 1-8 involved in cyclic bond formation
Chirality	Cyclic
Nature	11
Source	D
Origin	Cationic
Species	Natural
Strain	Derived from Callyspongia aerizusa
Cell Line	IC90 = >100 Î¼g/ml
Inhibition Concentration	in vitro
Sequence	2015
Cytotoxicity	THP-1 cell line
In vivo Model	90% reduction in bacterial load
Lethal Dose	NA
Immune Responce	NA
Mechanism of Action	NA
Target	NA
Combination Therapy	NA
Other activities	NA
PMID	NA
Year of Publication	NA
Tertiary Structure (Technique)	Not Predicted),

Primary information
ID	antitb_1646,
Name	26213786
N-Terminal modification	Callyaerins 8
C-Terminal Modification	H-(Hyp)-LLPPVPLFG
Chemical Modification	Free
Linear/Cyclic	Amidation
Length	Hyp= Hydroxiproline, Residue 1-8 involved in cyclic bond formation
Chirality	Cyclic
Nature	11
Source	D
Origin	Cationic
Species	Natural
Strain	Derived from Callyspongia aerizusa
Cell Line	IC50= >100 Î¼g/ml
Inhibition Concentration	in vitro
Sequence	2015
Cytotoxicity	MRC-5 cell lines
In vivo Model	50% reduction in bacterial load
Lethal Dose	NA
Immune Responce	NA
Mechanism of Action	NA
Target	NA
Combination Therapy	NA
Other activities	NA
PMID	NA
Year of Publication	NA
Tertiary Structure (Technique)	Not Predicted),

Primary information
ID	antitb_1647,
Name	26213786
N-Terminal modification	Callyaerins 8
C-Terminal Modification	H-(Hyp)-LLPPVPLFG
Chemical Modification	Free
Linear/Cyclic	Amidation
Length	Hyp= Hydroxiproline, Residue 1-8 involved in cyclic bond formation
Chirality	Cyclic
Nature	11
Source	D
Origin	Cationic
Species	Natural
Strain	Derived from Callyspongia aerizusa
Cell Line	IC90 = 100 Î¼g/ml
Inhibition Concentration	in vitro
Sequence	2015
Cytotoxicity	MRC-5 cell lines
In vivo Model	90% reduction in bacterial load
Lethal Dose	NA
Immune Responce	NA
Mechanism of Action	NA
Target	NA
Combination Therapy	NA
Other activities	NA
PMID	NA
Year of Publication	NA
Tertiary Structure (Technique)	Not Predicted),