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FWGLKGLKKFSKKL details |
Primary information | |
---|---|
ID | antitb_1191, |
Name | 25019413 |
N-Terminal modification | Pin2 [14] |
C-Terminal Modification | FWGLKGLKKFSKKL |
Chemical Modification | Free |
Linear/Cyclic | Free |
Length | None |
Chirality | Linear |
Nature | 14 |
Source | L |
Origin | Cationic |
Species | Synthetic |
Strain | Short variant of Pin2 |
Inhibition Concentration | Mycobacterium tuberculosis |
In Vitro/ In vivo | Mycobacterium tuberculosis H37Rv |
Cell Line | MIC = 20 ± 6.92 μg/ml or 11.92 ± 3.7 μM |
Inhibition Concentration | In vitro |
Sequence | 2014 |
Cytotoxicity | RBC |
In vivo Model | NA |
Lethal Dose | Hemolysis ( IC-50 = 418.4 [291–602]) |
Immune Responce | None |
Mechanism of Action | NA |
Target | NA |
Combination Therapy | Cell wall disruption |
Other activities | Cell wall |
PMID | None |
Year of Publication | Anti-bacterial (E. coli, S. aureus) |
Tertiary Structure (Technique) | Not Predicted), |
Primary information | |
---|---|
ID | antitb_1192, |
Name | 25019413 |
N-Terminal modification | Pin2 [14] |
C-Terminal Modification | FWGLKGLKKFSKKL |
Chemical Modification | Free |
Linear/Cyclic | Free |
Length | None |
Chirality | Linear |
Nature | 14 |
Source | L |
Origin | Cationic |
Species | Synthetic |
Strain | Short variant of Pin3 |
Inhibition Concentration | Mycobacterium tuberculosis |
In Vitro/ In vivo | Mycobacterium tuberculosis muti-drug resistant strain (MDR) clinical isolate |
Cell Line | MIC = 10 ± 3.1 μg/ml or 6 ± 1.8 μM |
Inhibition Concentration | In vitro |
Sequence | 2014 |
Cytotoxicity | RBC |
In vivo Model | NA |
Lethal Dose | Hemolysis ( IC-50 = 418.4 [291–602]) |
Immune Responce | None |
Mechanism of Action | NA |
Target | NA |
Combination Therapy | Cell wall disruption |
Other activities | Cell wall |
PMID | None |
Year of Publication | Anti-bacterial (E. coli, S. aureus) |
Tertiary Structure (Technique) | Not Predicted), |