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FRCRRWQWRMRRLG details |
| Primary information | |
|---|---|
| ID | antitb_1181, |
| Name | 24709266 |
| N-Terminal modification | LFcin17-30 all R |
| C-Terminal Modification | FRCRRWQWRMRRLG |
| Chemical Modification | Free |
| Linear/Cyclic | Free |
| Length | None |
| Chirality | Linear |
| Nature | 14 |
| Source | L |
| Origin | Cationic |
| Species | Synthetic |
| Inhibition Concentration | Mycobacterium avium |
| In Vitro/ In vivo | Mycobacterium avium strain 2447 smooth transparent variant (SmT) |
| Cell Line | IC50 = 10.8 ± 1.6 |
| Inhibition Concentration | In vitro |
| Sequence | 2014 |
| Cytotoxicity | None |
| In vivo Model | NA |
| Lethal Dose | NA |
| Immune Responce | None |
| Mechanism of Action | NA |
| Target | NA |
| Combination Therapy | Permeabilization of peptide causes significant changes both in the surface and in the ultrastructural organization of the mycobacterial cells. |
| Other activities | Cell envelope |
| PMID | None |
| Year of Publication | None |
| Tertiary Structure (Technique) | Not Predicted), |
| Primary information | |
|---|---|
| ID | antitb_1182, |
| Name | 24709266 |
| N-Terminal modification | LFcin17-30 all R |
| C-Terminal Modification | FRCRRWQWRMRRLG |
| Chemical Modification | Free |
| Linear/Cyclic | Free |
| Length | None |
| Chirality | Linear |
| Nature | 14 |
| Source | L |
| Origin | Cationic |
| Species | Synthetic |
| Inhibition Concentration | Mycobacterium avium |
| In Vitro/ In vivo | Mycobacterium avium strain 2447 smooth transparent variant (SmT) |
| Cell Line | IC90 = 19.3 ± 4.8 |
| Inhibition Concentration | In vitro |
| Sequence | 2014 |
| Cytotoxicity | None |
| In vivo Model | NA |
| Lethal Dose | NA |
| Immune Responce | None |
| Mechanism of Action | NA |
| Target | NA |
| Combination Therapy | Permeabilization of peptide causes significant changes both in the surface and in the ultrastructural organization of the mycobacterial cells. |
| Other activities | Cell envelope |
| PMID | None |
| Year of Publication | None |
| Tertiary Structure (Technique) | Not Predicted), |
| Primary information | |
|---|---|
| ID | antitb_1910, |
| Name | 24709266 |
| N-Terminal modification | Bovine lactoferricin 17-30 all R |
| C-Terminal Modification | FRCRRWQWRMRRLG |
| Chemical Modification | Free |
| Linear/Cyclic | Free |
| Length | None |
| Chirality | Linear |
| Nature | 14 |
| Source | L |
| Origin | Cationic |
| Species | Natural |
| Strain | Derived from bovine lactoferricin protein |
| Inhibition Concentration | Mycobacterium avium |
| In Vitro/ In vivo | Mycobacterium avium |
| Cell Line | Mycobacterium avium 2447 smT |
| Inhibition Concentration | In vitro |
| Sequence | 2014 |
| Cytotoxicity | NA |
| In vivo Model | Tratment with this concentration inhibit 50% bacterial growth |
| Lethal Dose | NA |
| Immune Responce | NA |
| Mechanism of Action | NA |
| Target | NA |
| Combination Therapy | NA |
| Other activities | Lipid bilayer |
| PMID | NA |
| Year of Publication | NA |
| Tertiary Structure (Technique) | Not Predicted), |
| Primary information | |
|---|---|
| ID | antitb_1911, |
| Name | 24709266 |
| N-Terminal modification | Bovine lactoferricin 17-30 all R |
| C-Terminal Modification | FRCRRWQWRMRRLG |
| Chemical Modification | Free |
| Linear/Cyclic | Free |
| Length | None |
| Chirality | Linear |
| Nature | 14 |
| Source | L |
| Origin | Cationic |
| Species | Natural |
| Strain | Derived from bovine lactoferricin protein |
| Inhibition Concentration | Mycobacterium avium |
| In Vitro/ In vivo | Mycobacterium avium |
| Cell Line | Mycobacterium avium 2447 smT |
| Inhibition Concentration | In vitro |
| Sequence | 2014 |
| Cytotoxicity | NA |
| In vivo Model | Tratment with this concentration inhibit 90% bacterial growth |
| Lethal Dose | NA |
| Immune Responce | NA |
| Mechanism of Action | NA |
| Target | NA |
| Combination Therapy | NA |
| Other activities | Lipid bilayer |
| PMID | NA |
| Year of Publication | NA |
| Tertiary Structure (Technique) | Not Predicted), |