Primary information |
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ID | antitb_1962 |
Peptide Name | Wollamide- B |
Sequence | WLlIXx |
N-terminal Modification | Free |
C-terminal Modification | Free |
Chemical Modification | Third residue is D-leucine, fifth residue is tertiary butyl serine and x= ornithine |
Linear/ Cyclic | Cyclic |
Length | 6 |
Chirality | D |
Nature | Cationic |
Source | Synthetic |
Origin | NA |
Species | Mycobacterium tuberculosis |
Strain | Mycobacterium tuberculosis H37Rv |
Inhibition Concentartion | MIC = 40 μM |
In vitro/In vivo | In vitro |
Cell Line | HepG2 cell line |
Inhibition Concentartion | NA |
Cytotoxicity | Cytoxic above > 100 μM |
In vivo Model | NA |
Lethal Dose | NA |
Immune Response | NA |
Mechanism of Action | NA |
Target | cell wall pore formation |
Combination Therapy | NA |
Other Activities | NA |
Pubmed ID | 28423019 |
Year of Publication | 2017 |
3-D Structure | NA |