| Primary information |
|---|
| ID | antitb_1945 |
| Peptide Name | Peptide-8 |
| Sequence | GF(A6c)G(Tic)K(A6c)G(Tic)F(A6c)G(Tic)GK(Tic)KKKK |
| N-terminal Modification | Acetylation |
| C-terminal Modification | Amidation |
| Chemical Modification | Tic = Tetrahydroisoquinolinecarboxylic acid, A6c 1-aminocyclohexane carboxylic acid |
| Linear/ Cyclic | Linear |
| Length | 20 |
| Chirality | D |
| Nature | Cationic |
| Source | Synthetic |
| Origin | NA |
| Species | Mycobacterium tuberculosis |
| Strain | Mycobacterium tuberculosis XDR |
| Inhibition Concentartion | MIC = 20.6μM |
| In vitro/In vivo | In vitro |
| Cell Line | NA |
| Inhibition Concentartion | NA |
| Cytotoxicity | NA |
| In vivo Model | NA |
| Lethal Dose | NA |
| Immune Response | NA |
| Mechanism of Action | NA |
| Target | Cell wall pore formation |
| Combination Therapy | NA |
| Other Activities | Antibacterial against Enterobacter aerogenes, Acinetobacter baumannii, Psuedomonas aeruginosa, Klebsiella pneumoniae, Eenterococcus faecalis, Staphylococcus aureus |
| Pubmed ID | 27387357 |
| Year of Publication | 2016 |
| 3-D Structure | NA |