Detailed description page of AntiTbPdb
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antitb_1914 details |
| Primary information | |
|---|---|
| ID | antitb_1914 |
| Peptide Name | None |
| Sequence | ILSLRWRWKWWKK |
| N-terminal Modification | Free |
| C-terminal Modification | Free |
| Chemical Modification | None |
| Linear/ Cyclic | Linear |
| Length | 13 |
| Chirality | L |
| Nature | Cationic |
| Source | Synthetic |
| Origin | NA |
| Species | Mycobacterium bovis |
| Strain | Mycobacterium bovis BCG pasteur strain |
| Inhibition Concentartion | MIC = 32 μM |
| In vitro/In vivo | In vitro |
| Cell Line | J774.16 mouse macrophages and A549 human lung epithelial cells |
| Inhibition Concentartion | NA |
| Cytotoxicity | No cytotoxicity against J774.16 mouse macrophages and A549 human lung epithelial cells |
| In vivo Model | NA |
| Lethal Dose | NA |
| Immune Response | NA |
| Mechanism of Action | NA |
| Target | Lipid bilayer |
| Combination Therapy | NA |
| Other Activities | Antibacterial against Streptococcus pyogenes, Streptococcus agalactiae, Streptococcus pneumoniae ATCC 49619, Klebsiella pneumoniae, Pseudomonas aeruginosa ATCC 27853, Bacillus subtilis BGSC 1A1. |
| Pubmed ID | 26902758 |
| Year of Publication | 2016 |
| 3-D Structure | NA |