Primary information |
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ID | antitb_1882 |
Peptide Name | Propeptin-2 |
Sequence | GYPWWDYRDLFGGHTFI |
N-terminal Modification | Involved in Cyclic bond formation between amino acid 1 and 9 |
C-terminal Modification | Free |
Chemical Modification | None |
Linear/ Cyclic | Cyclic |
Length | 17 |
Chirality | D |
Nature | NA |
Source | Natural |
Origin | Isolated from Microbispora species SNA-115 |
Species | Mycobacterium phlei |
Strain | Mycobacterium phlei IFO 3158 |
Inhibition Concentartion | 40 μg/disc |
In vitro/In vivo | In vitro |
Cell Line | NA |
Inhibition Concentartion | Treatment of infected Mycobacterium phlei with 40 μg/disc of Propeptin-2 decreased approximately 90% of the bacterial load in zone inhibition assay |
Cytotoxicity | NA |
In vivo Model | NA |
Lethal Dose | NA |
Immune Response | NA |
Mechanism of Action | NA |
Target | NA |
Combination Therapy | None |
Other Activities | Antibacterial against silkworm |
Pubmed ID | 17827663 |
Year of Publication | 2007 |
3-D Structure | NA |