| Primary information |
|---|
| ID | antitb_1868 |
| Peptide Name | Anoplin |
| Sequence | GLLKFIKKLL |
| N-terminal Modification | Addition of dodecanoic acid (C12H24O2) |
| C-terminal Modification | Amidation |
| Chemical Modification | None |
| Linear/ Cyclic | Linear |
| Length | 10 |
| Chirality | L |
| Nature | Amphipathic |
| Source | Synthetic |
| Origin | Anlogue of Anoplin |
| Species | Mycobacterium smegmatis |
| Strain | Mycobacterium smegmatis mc2 163 |
| Inhibition Concentartion | MIC = 5 μg/mL |
| In vitro/In vivo | In vitro |
| Cell Line | RBC |
| Inhibition Concentartion | NA |
| Cytotoxicity | Non toxic to erythrocytes |
| In vivo Model | NA |
| Lethal Dose | NA |
| Immune Response | NA |
| Mechanism of Action | NA |
| Target | NA |
| Combination Therapy | NA |
| Other Activities | Antifungal (C. parapsilosis) and Antibacterial (Escherichia coli DH5a, Pseudomonas aeruginosa PAO, and Zymomonas mobilis ATCC 10988; Gram-positive bacteria: Bacillus subtilis DELTA) |
| Pubmed ID | 27862650 |
| Year of Publication | 2016 |
| 3-D Structure | NA |