Primary information |
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ID | antitb_1747 |
Peptide Name | FKAB-1Gg |
Sequence | GF-Tic-GK-Tic-GF-Tic-GK-Tic-KKKK |
N-terminal Modification | Acetylation |
C-terminal Modification | Amidation |
Chemical Modification | Tic = tetrahydroisoquinolinecarboxylic acid |
Linear/ Cyclic | Linear |
Length | 16 |
Chirality | L |
Nature | Hydrophobic |
Source | Synthetic |
Origin | NA |
Species | Mycobacterium ranae |
Strain | Mycobacterium ranae |
Inhibition Concentartion | MIC = 30 μM |
In vitro/In vivo | Both |
Cell Line | RBC |
Inhibition Concentartion | NA |
Cytotoxicity | 6 % hemolysis at 100 μM and 4.9 % at 25 μM |
In vivo Model | Mice |
Lethal Dose | NA |
Immune Response | NA |
Mechanism of Action | NA |
Target | NA |
Combination Therapy | None |
Other Activities | Anti-bacterial (Salmonella typhimurium, Staphylococcus aureus, Bacillus subtillis) |
Pubmed ID | US 2012/0197004 |
Year of Publication | 2012 |
3-D Structure | NA |