| Primary information |
|---|
| ID | antitb_1738 |
| Peptide Name | FKAB-1G |
| Sequence | GF-Tic-Oic-GK-Tic-Oic-GF-Tic-Oic-GK-Tic-KKKK |
| N-terminal Modification | Acetylation |
| C-terminal Modification | Amidation |
| Chemical Modification | Tic = tetrahydroisoquinolinecarboxylic acid, Oic = Octahydroindolecarboxylic acid |
| Linear/ Cyclic | Linear |
| Length | 19 |
| Chirality | L |
| Nature | Hydrophobic |
| Source | Synthetic |
| Origin | NA |
| Species | Mycobacterium ranae |
| Strain | Mycobacterium ranae |
| Inhibition Concentartion | MIC = 10 μM |
| In vitro/In vivo | Both |
| Cell Line | RBC |
| Inhibition Concentartion | NA |
| Cytotoxicity | 14 % hemolysis at 100 and 25 μM |
| In vivo Model | Mice |
| Lethal Dose | No observed toxicity at 5 and 25 mg/kg but minor |
| Immune Response | NA |
| Mechanism of Action | NA |
| Target | NA |
| Combination Therapy | None |
| Other Activities | Anti-bacterial (Salmonella typhimurium, Staphylococcus aureus, Bacillus subtillis) |
| Pubmed ID | US 2012/0197004 |
| Year of Publication | 2012 |
| 3-D Structure | NA |