| Primary information |
|---|
| ID | antitb_1732 |
| Peptide Name | Seq ID No 22 |
| Sequence | YPHHFKHRHIPIGGGS |
| N-terminal Modification | Free |
| C-terminal Modification | Free |
| Chemical Modification | None |
| Linear/ Cyclic | Linear |
| Length | 16 |
| Chirality | L |
| Nature | NA |
| Source | Synthetic |
| Origin | From random peptide libraries diplayed on bacteriophage M14 |
| Species | Mycobacterium tuberculosis |
| Strain | Mycobacterium tuberculosis |
| Inhibition Concentartion | 100 μM completely inhibits the cahpaeron activity of Hsp 16.3 |
| In vitro/In vivo | In vitro |
| Cell Line | Mouse bone marrow derive dmacrophages and THP-1 |
| Inhibition Concentartion | NA |
| Cytotoxicity | NA |
| In vivo Model | None |
| Lethal Dose | NA |
| Immune Response | NA |
| Mechanism of Action | Inhibit chaperon activity of heat shock protein 16.3 (Hsp 16.3) |
| Target | Heat shock protein (Hsp 16.3) |
| Combination Therapy | None |
| Other Activities | None |
| Pubmed ID | US 2007/003721 |
| Year of Publication | 2007 |
| 3-D Structure |  View in Jmol or Download Structure |