Primary information |
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ID | antitb_1650 |
Peptide Name | Tuftsin peptide conjugate compound |
Sequence | SEFAYGSFVRTVSLPV |
N-terminal Modification | INH is conjugated |
C-terminal Modification | Free |
Chemical Modification | None |
Linear/ Cyclic | Cyclic |
Length | 16 |
Chirality | L |
Nature | Cationic |
Source | Natural |
Origin | Derived from 16-kDa protein of M. tuberculosis and tuftsin-derived peptides |
Species | Mycobacterium Tuberculosis |
Strain | Mycobacterium tuberculosis H37Rv ATCC 27294 |
Inhibition Concentartion | MIC = 2.26μg/ml |
In vitro/In vivo | in vitro |
Cell Line | NA |
Inhibition Concentartion | NA |
Cytotoxicity | NA |
In vivo Model | NA |
Lethal Dose | NA |
Immune Response | NA |
Mechanism of Action | Cell wall biosynthesis inhibition |
Target | NA |
Combination Therapy | Peptide + INH(0.24 ug/ml) |
Other Activities | NA |
Pubmed ID | 19319854 |
Year of Publication | 2009 |
3-D Structure | NA |