Primary information |
---|
ID | antitb_1638 |
Peptide Name | Callyaerins 7 |
Sequence | I-(Hyp)-VILPPLPIFG |
N-terminal Modification | Free |
C-terminal Modification | Amidation |
Chemical Modification | Hyp= Hydroxiproline, Residue 1-8 involved in cyclic bond formation |
Linear/ Cyclic | Cyclic |
Length | 11 |
Chirality | D |
Nature | Cationic |
Source | Natural |
Origin | Derived from Callyspongia aerizusa |
Species | NA |
Strain | NA |
Inhibition Concentartion | IC50= 5 μg/ml |
In vitro/In vivo | in vitro |
Cell Line | THP-1 cell line |
Inhibition Concentartion | 50% reduction in bacterial load |
Cytotoxicity | NA |
In vivo Model | NA |
Lethal Dose | NA |
Immune Response | NA |
Mechanism of Action | NA |
Target | NA |
Combination Therapy | NA |
Other Activities | NA |
Pubmed ID | 26213786 |
Year of Publication | 2015 |
3-D Structure | NA |