| Primary information |
|---|
| ID | antitb_1632 |
| Peptide Name | Callyaerins 6 |
| Sequence | I-(Hyp)-VILPPLPIFG |
| N-terminal Modification | Free |
| C-terminal Modification | Amidation |
| Chemical Modification | Hyp= Hydroxiproline, Residue 1-8 involved in cyclic bond formation |
| Linear/ Cyclic | Cyclic |
| Length | 12 |
| Chirality | D |
| Nature | Cationic |
| Source | Natural |
| Origin | Derived from Callyspongia aerizusa |
| Species | NA |
| Strain | in vitro on THP1 cell line |
| Inhibition Concentartion | IC50= 30 μg/ml |
| In vitro/In vivo | in vitro |
| Cell Line | THP-1 cell line |
| Inhibition Concentartion | 50% reduction in bacterial load |
| Cytotoxicity | NA |
| In vivo Model | NA |
| Lethal Dose | NA |
| Immune Response | NA |
| Mechanism of Action | NA |
| Target | NA |
| Combination Therapy | NA |
| Other Activities | NA |
| Pubmed ID | 26213786 |
| Year of Publication | 2015 |
| 3-D Structure | NA |