| Primary information |
|---|
| ID | antitb_1624 |
| Peptide Name | CC |
| Sequence | CLLKKLLKKC |
| N-terminal Modification | Free |
| C-terminal Modification | Amidation |
| Chemical Modification | None |
| Linear/ Cyclic | Linear |
| Length | 10 |
| Chirality | L |
| Nature | Cationic |
| Source | Synthetic |
| Origin | NA |
| Species | Mycobacterium smegmatis |
| Strain | Mycobacterium smegmatis ATCC14468 |
| Inhibition Concentartion | MIC = 250 μg/ml |
| In vitro/In vivo | in vitro |
| Cell Line | RAW 264.7 mouse macrophage |
| Inhibition Concentartion | NA |
| Cytotoxicity | HC50= >500 μg/ml |
| In vivo Model | NA |
| Lethal Dose | NA |
| Immune Response | NA |
| Mechanism of Action | Bacterial membrane pore formation |
| Target | NA |
| Combination Therapy | Peptide + Rifampicin (0.98 μg/ml) |
| Other Activities | NA |
| Pubmed ID | 26380930 |
| Year of Publication | 2015 |
| 3-D Structure |  View in Jmol or Download Structure |